Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Vladimir Markov"'
Autor:
Tanaya Roychowdhury, Seth W. McNutt, Chiranjeevi Pasala, Hieu T. Nguyen, Daniel T. Thornton, Sahil Sharma, Luke Botticelli, Chander S. Digwal, Suhasini Joshi, Nan Yang, Palak Panchal, Souparna Chakrabarty, Sadik Bay, Vladimir Markov, Charlene Kwong, Jeanine Lisanti, Sun Young Chung, Stephen D. Ginsberg, Pengrong Yan, Elisa De Stanchina, Adriana Corben, Shanu Modi, Mary L. Alpaugh, Giorgio Colombo, Hediye Erdjument-Bromage, Thomas A. Neubert, Robert J. Chalkley, Peter R. Baker, Alma L. Burlingame, Anna Rodina, Gabriela Chiosis, Feixia Chu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract The intricate network of protein-chaperone interactions is crucial for maintaining cellular function. Recent discoveries have unveiled the existence of specialized chaperone assemblies, known as epichaperomes, which serve as scaffolding plat
Externí odkaz:
https://doaj.org/article/2f7ed5a1fa2f46d69f151277d59c0181
Autor:
Hidenori Kitai, Philip H. Choi, Yu C. Yang, Jacob A. Boyer, Adele Whaley, Priya Pancholi, Claire Thant, Jason Reiter, Kevin Chen, Vladimir Markov, Hirokazu Taniguchi, Rui Yamaguchi, Hiromichi Ebi, James Evans, Jingjing Jiang, Bianca Lee, David Wildes, Elisa de Stanchina, Jacqueline A. M. Smith, Mallika Singh, Neal Rosen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Current KRASG12C (OFF) inhibitors that target inactive GDP-bound KRASG12C cause responses in less than half of patients and these responses are not durable. A class of RASG12C (ON) inhibitors that targets active GTP-bound KRASG12C blocks ERK
Externí odkaz:
https://doaj.org/article/7ad6de68f66945a2a3cb9c50ceaaf9b5
Publikováno v:
Energy Science & Engineering, Vol 10, Iss 2, Pp 552-577 (2022)
Abstract In the paper, the method based on optimization of flow passage geometry of diesel injector nozzle to improve the quality of fuel injection and atomization process has been studied. Designs of injector nozzles have been developed to enhance t
Externí odkaz:
https://doaj.org/article/03d65e2409784dcb9e962ddd3089a4ad
Autor:
Jeremy S. Francis, Vladimir Markov, Irenuez D. Wojtas, Steve Gray, Thomas McCown, R. Jude Samulski, Marciano Figueroa, Paola Leone
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 520-534 (2021)
Recent advances in adeno-associated viral (AAV) capsid variants with novel oligotropism require validation in models of disease in order to be viable candidates for white matter disease gene therapy. We present here an assessment of the biodistributi
Externí odkaz:
https://doaj.org/article/b01784b4f1824fefaae134f8465d61b6
Publikováno v:
Combustion Engines, Vol 178, Iss 3, Pp 129-134 (2019)
The article presents a method for determining the quality of spraying a mixture of oil and synthetic fuels obtained from the pro-cessing of polymer materials. Laboratory tests of physical parameters of such a mixture were carried out, which made it p
Externí odkaz:
https://doaj.org/article/c991685560954d72bf40293fab8ea4e1
Autor:
Vladimir Markov, Vyacheslav Kamaltdinov, Sergey Devyanin, Bowen Sa, Anatoly Zherdev, Viktor Furman
Publikováno v:
Resources, Vol 10, Iss 8, p 74 (2021)
Biofuels derived from renewable plant materials are considered promising alternative fuels to decrease emissions of ICEs. This study aimed to justify the possibility of using vegetable oils of different sources as a 10% additive in blended biofuel fo
Externí odkaz:
https://doaj.org/article/aa66287485d545e69b1406755082857a
Autor:
Jeremy S. Francis, PhD, Ireneusz Wojtas, PhD, Vladimir Markov, MD, Steven J. Gray, PhD, Thomas J. McCown, PhD, R. Jude Samulski, PhD, Larissa T. Bilaniuk, MD, Dah-Jyuu Wang, PhD, Darryl C. De Vivo, MD, Christopher G. Janson, MD, Paola Leone, PhD
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 323-334 (2016)
Breakdown of neuro-glial N-acetyl-aspartate (NAA) metabolism results in the failure of developmental myelination, manifest in the congenital pediatric leukodystrophy Canavan disease caused by mutations to the sole NAA catabolizing enzyme aspartoacyla
Externí odkaz:
https://doaj.org/article/36bbbc38714a4910a6a154ba0ec668da
Autor:
Marina Katkova, Vladimir Markov
Publikováno v:
Известия Томского политехнического университета: Инжиниринг георесурсов, Vol 325, Iss 6 (2019)
Relevance of the research is caused by the need of modeling institutional nonequilibrium economy taking into account escalating effect of transaction hysteresis. The main aim of the research is to justify the transaction hysteresis effect in developm
Externí odkaz:
https://doaj.org/article/b95de6e919b84a16a3b2b8b65edd7df1
Autor:
Vladimir Markov, Vyacheslav Kamaltdinov, Anatoliy Zherdev, Viktor Furman, Bowen Sa, Vsevolod Neverov
Publikováno v:
Energies, Vol 12, Iss 22, p 4345 (2019)
The relevance of this article is due to the need for improving indicators of exhaust gas toxicity of diesel engines. One of the modern directions of achieving the required environmental performance of diesel engines is the addition of various nanomat
Externí odkaz:
https://doaj.org/article/676a4a9c188d437e96e14e54fb6ef305
Autor:
Arielle Elkrief, Igor Odintsov, Vladimir Markov, Rebecca Caeser, Pawel Sobczuk, Sam E. Tischfield, Umesh Bhanot, Chad M. Vanderbilt, Emily Cheng, Alexander Drilon, Gregory J. Riely, William W. Lockwood, Elisa de Stanchina, Vijaya G. Tirunagaru, Robert C. Doebele, Álvaro Quintanal-Villalonga, Charles M. Rudin, Romel Somwar, Marc Ladanyi
Publikováno v:
Journal of Thoracic Oncology.