Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Vladimir M. Shkumatov"'
Autor:
Anastasiya Dudko, Matvey S. Horetski, Nina S. Frolova, Yaroslav V. Faletrov, Vladimir M. Shkumatov
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 1, Pp 61-71 (2022)
A fluorescent molecular rotor (FMR) based on boron dipyrromethene core was obtained. Fluorescence emission properties of the compound strongly depend on the medium viscosity. The emission intensity increases 27 times after viscosity changing from eth
Externí odkaz:
https://doaj.org/article/6297328754234b22b514f3f194af4a52
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 1, Pp 53-60 (2022)
Polylactide (PLA) is one of the most promising biodegradable and biocompatible polymer materials. Estimation of hydrolytic destruction of PLA is of high importance for their applications both at planning and at real-time exploitation. This paper repo
Externí odkaz:
https://doaj.org/article/cec1ce0a4ace4746bc76c9d30ef4ff9d
Autor:
Jan U. Panada, Valeriya A. Klopava, Tatsiana A. Kulahava, Yaroslav V. Faletrov, Matvey S. Horetski, Nina S. Frolova, Siarhei V. Koran, Elena G. Fomina, Vladimir M. Shkumatov
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 1, Pp 43-52 (2022)
A 3-acetyl analogue of 5-hydroxyindole was synthesised and evaluated for its effects on rat C6 glioma cell functions. It was found that 3-acetyl-5-hydroxy-2-methylindole at 10 μmol/L led to a sharp reduction of mitochondrial membrane potential, indu
Externí odkaz:
https://doaj.org/article/fc888ecc852b41829d38921170bc9b92
Autor:
Yaroslav V. Faletrov, Veronika S. Karpushenkova, Viktoryia A. Zavalinich, Polina S. Yakovets, Anastasia D. Shkredava, Vladimir M. Shkumatov
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 2, Pp 25-35 (2021)
Albumin is a globular protein of plasma of mammalian blood participating in transport of hydrophobic metabolites and drugs. Thus, studies devoted to its binding are valuable as a part of evaluation of new potential drugs or fluorescent probes for in
Externí odkaz:
https://doaj.org/article/daf6af8ca8e147dcb1086e2a69ae2728
Autor:
Yaroslav V. Faletrov, Liliya I. Glinskaya, Matvey S. Horetski, Jan V. Panada, Nina S. Frolova, Vladimir M. Shkumatov
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 1, Pp 21-27 (2021)
Cytochromes P450 are hem-containing monooxygenases which catalyse biosynthesis of many compounds playing an essential role in cellular functions as well as degradation of drugs and xenobiotics. Some P450s (e. g., human CYP19 and CYP17, fungal CYP51)
Externí odkaz:
https://doaj.org/article/aabce7a169f94000b8e64dbb869bd8b8
Autor:
Veronika S. Karpushenkova, Liliya I. Glinskaya, Yaroslav V. Faletrov, Kseniia N. Bardakova, Yuliya A. Piskun, Sergei V. Kostjuk, Vladimir M. Shkumatov
Publikováno v:
Chemistry Proceedings, Vol 12, Iss 1, p 66 (2022)
There is a trend to find new ways of using photocatalysis in order to synthesize valuable products or to control or track live processes with special fluorescence-based molecular probes. The paper presents some results concerning new photochemical pr
Externí odkaz:
https://doaj.org/article/dcaefe9504a34b83b0d95e220d728be4
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 1, Pp 28-34 (2018)
In this work we describe the modeling of interactions between indole steroids and steroidogenic cytochromes P450. The highest possible affinity is expected of enzymes involved in cholesterol transformation (i. e. CYP3A4, CYP7A1, CYP11A1). In case of
Externí odkaz:
https://doaj.org/article/d5de38aef5894a538596a5ab52ea390d
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 1, Pp 22-27 (2018)
In silico docking simulations of interactions between BODIPY-based fluorescent compounds and mammalian proteins, responsible for steroidogenesis, namely, cytochromes P450: CYP11A1, CYP17A1, CYP19A1, CYP7A1 and STARD1 transport protein, have been perf
Externí odkaz:
https://doaj.org/article/f1e4aa4543004fa69b9342a5987e95a2
Autor:
Veronika S. Karpushenkova, Viktoryia A. Zavalinich, Vladimir M. Shkumatov, Y. V. Faletrov, Anastasia D. Shkredava, Polina S. Yakovets
Publikováno v:
Журнал Белорусского государственного университета: Химия, Iss 2, Pp 25-35 (2021)
Albumin is a globular protein of plasma of mammalian blood participating in transport of hydrophobic metabolites and drugs. Thus, studies devoted to its binding are valuable as a part of evaluation of new potential drugs or fluorescent probes for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71d462559b94af4321965496667a6c6
https://journals.bsu.by/index.php/chemistry/article/view/4099
https://journals.bsu.by/index.php/chemistry/article/view/4099
Autor:
N. S. Frolova, Y. V. Faletrov, M. S. Horetski, E. V. Rudaya, E. V. Andrievskaya, Anna Brzostek, K. A. Gilep, Aleksandra S. Falchevskaya, Renata Plocinska, J. V. Panada, Vladimir M. Shkumatov
Publikováno v:
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry. 15:111-118
Molecular docking of four isoniazid hydrazones including steroids dehydroepiandrosterone, pregnenolone, 16α,17α-epoxypregnenolone, and cholestenone (IDHEA, IPRE, IEP5, ICHN), to mycobacterial cytochromes P450 was performed. The in silico study has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05f122c8e32ac22ed6a9abffd652bc8d
https://doi.org/10.1134/s1990750821020037
https://doi.org/10.1134/s1990750821020037