Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vladimir Larichev"'
Publikováno v:
Organic Process Research & Development. 24:2853-2863
The synthesis of a subtype-selective inhibitor BACE-1 inhibitor is presented. One of the key transformations in this sequence is the conversion of a thiourea to the bicyclic 1,3-aminooxazine. This ...
Publikováno v:
European Journal of Organic Chemistry. 2010:6824-6830
A two-step entry to a chemically robust, hindered P,O-type phosphorinane-based ligand and its application toward Pd-mediated cross-coupling reactions of unactivated aryl chlorides is presented.
Autor:
Carly Griffin, Nick Henry Werstiuk, Vladimir Larichev, Siyaram Pandey, Joanna Poloczek, James McNulty
Publikováno v:
Planta Medica. 73:1543-1547
The occurrence of two butenolides, menisdaurilide and aquilegiolide, in commercial specimens of Dicentra spectabilis is reported for the first time; a rapid and direct isolation protocol is described. The ability of these lactones to induce apoptosis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:5315-5318
The synthesis of 3-deoxydihydrolycoricidine, a key element toward elucidation of the pancratistatin anticancer pharmacophore, is described. Biological evaluation of this compound showed it to be significantly less active against tumor cells than panc
Publikováno v:
Letters in Organic Chemistry. 1:137-139
Trihexyl(tetradecyl)phoshonium decanoate was shown to be an effective promoter for the Henry nitroaldol reaction of nitromethane with aromatic aldehydes. A mechanism is proposed involving Lewis acid activation of the carbonyl group proceeding through
Publikováno v:
ChemInform. 42
The novel catalyst is applied to the reaction of aryl halides with boronic acids or amines.
Autor:
Vitali I. Tararov, Nikolai S. Ikonnikov, Lidia V. Yashkina, Michael North, Vladimir Larichev, Yu. N. Belokon, C. Orizu, Margarita A. Moscalenko
Publikováno v:
ChemInform. 30
The enantiomeric purity (ee) of the addition product of Me3SiCN to PhCHO at ∼20 °C catalyzed by chiral TiIV complexes, which were preparedin situ from Ti(OPri)4 and the Schiff bases (condensation products of substituted salicylaldehydes with (1R,
Autor:
Nicolai S. Ikonnikov, L. V. Yashkina, Vladimir Larichev, Michael North, M. A. Moskalenko, Yuri N. Belokon, Andrey Gutnov, Denis E. Lesovoy
Publikováno v:
ChemInform. 33
A (salen)titanium catalyst has been found to induce the asymmetric addition of potassium cyanide and acetic anhydride to aldehydes, giving enantiomerically enriched cyanohydrin esters with up to 92% enantiomeric excess using just 1 mol% of the cataly
Autor:
Margarita A. Moscalenko, Vitali I. Tararov, Michael North, Lidia V. Yashkina, Vladimir Larichev, Yu. N. Belokon, C. Orizu, Nikolai S. Ikonnikov
Publikováno v:
Russian Chemical Bulletin. 48:1128-1130
The enantiomeric purity (ee) of the addition product of Me3SiCN to PhCHO at ∼20 °C catalyzed by chiral TiIV complexes, which were preparedin situ from Ti(OPri)4 and the Schiff bases (condensation products of substituted salicylaldehydes with (1R,
Autor:
Sreedhar Cheekoori, Vladimir Larichev, Al Robertson, James McNulty, Alfredo Capretta, Jerald J. Nair
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 12(36)
A survey of substitution reactions conducted in a phosphonium bistriflimide ionic liquid is presented. The results demonstrate high selectivity favoring substitution over typically competitive elimination and solvolytic processes even when challengin