Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Vladimir K. Patchev"'
Autor:
Natalia eDmitrieva, Elizabeth K Faircloth, Stephen ePyatok, Frank eSacher, Vladimir K Patchev
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
Symptoms of endometriosis, among others, include pelvic/abdominal and muscle pain. Non-steroidal anti-inflammatory agents are first-line treatment for this pain. Similar to women, rats with surgically-induced endometriosis (ENDO), but not its surgica
Externí odkaz:
https://doaj.org/article/2704189625c94f69a3f6b31ad59bdf87
Autor:
Vladimir K. Patchev, Dorothee Girbig, Bernd-Wolfgang Igl, Maik Obendorf, Katja Prelle, Tanja Lehmann
Publikováno v:
Menopause. 19:909-915
Objective Estrogen supplementation is considered a reliable therapeutic approach to symptoms of vasomotor dysregulation (hot flashes) associated with the menopausal transition and sex hormone deprivation. Implication of changes in central neurotransm
Publikováno v:
Archives of Biochemistry and Biophysics. 460:56-66
Evidence is accumulating in support of the view that tissue-specific effects of steroid hormones depend on the recruitment of nuclear receptor comodulator proteins. The latter interact directly with the hormone receptors and modify their transcriptio
Publikováno v:
Dialogues in Clinical Neuroscience. 8:417-432
Illustrating the complexity of the stress response and its multifaceted manifestations is the leading idea of this overview of experimental paradigms used for stress induction in laboratory animals. The description of key features of models based on
Autor:
Vladimir K. Patchev, Maik Obendorf
Publikováno v:
Current Drug Target -Inflammation & Allergy. 3:425-433
Differential sex-specific liability to inflammatory and autoimmune diseases, and changes in symptom severity in association with physiological fluctuations in gonadal secretions are indicative of significant contribution of sex hormones to the regula
Publikováno v:
Experimental Gerontology. 39:1651-1660
The importance of androgen signaling is well recognized for numerous aspects of central nervous system (CNS) function, ranging from sex-specific organization of neuroendocrine and behavioral circuits to adaptive capacity, resistance and repair. Nonet
Autor:
Youriy Mitev, Osborne F. X. Almeida, Madeha H.A. Darwish, Florian Holsboer, Vladimir K. Patchev, Siegmund Wolf
Publikováno v:
Neuroscience. 120:541-549
The enzyme 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) is involved in the generation of neuroactive steroids through ring-A-reduction of hormonal precursors. We examined the developmental regulation of, gender differences in, and effects of ho
Publikováno v:
The FASEB Journal. 17:1-12
The regional distribution, developmental profiles, and gonadectomy- and estrogen-induced changes in the density of transcripts encoding the steroid receptor coactivator-1 (SRC-1) were examined in the female rat brain by semiquantitative in situ hybri
Publikováno v:
Neuroendocrinology. 67:171-180
Transient exposure of rats to high doses of dexamethasone (DEX; 500 µg/day for 5 days) produced a host of symptoms that are indicative of hypothalamic-pituitary-adrenal (HPA) axis dysregulation, such as increased adrenocortical secretion over 24 h,