Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Vladimir I. Romanenko"'
Autor:
Michael I. Treshalin, Dominique Schols, Alexander A. Shtil, Dmitry N. Kaluzhny, Yulia L. Volodina, Anastasia A. Kalinina, Yves Pommier, Maria N. Preobrazhenskaya, Vladimir B. Tsvetkov, Lyubov G. Dezhenkova, Helen M. Treshalina, Andrey E. Shchekotikhin, Yuri N. Luzikov, Vladimir I. Romanenko, Michael H.G. Kubbutat, Victor V. Tatarskiy
Publikováno v:
Eur J Med Chem
Anthraquinones and their analogues, in particular heteroarene-fused anthracendiones, are prospective scaffolds for new compounds with improved antitumor characteristics. We herein report the use of a ‘scaffold hopping’ approach for the replacemen
Autor:
Helen M. Treshalina, Dmitry N. Kaluzhny, Andrey E. Shchekotikhin, Aleksey Nikitin, Alexander S. Tikhomirov, Vladimir I. Romanenko, Michael I. Treshalin
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 109
To improve the water solubility of the anticancer drug candidate LCTA-2034 (A1), we investigated the formation of complexes of this anthrax[2,3-b]furan congener with the solubilizing 2-hydroxypropyl derivative of β-cyclodextrin HP-βCD (Cavitron®).
Autor:
Jan Balzarini, Yves Pommier, Dmitry N. Kaluzhny, V. N. Buyanov, Yuri N. Luzikov, Keli Agama, Nina A. Lesnaya, Andrey E. Shchekotikhin, Vladimir I. Romanenko, Valeria A. Glazunova, Helena M. Treshalina, Alexander A. Shtil, Maria N. Preobrazhenskaya, Lyubov G. Dezhenkova
Publikováno v:
European journal of medicinal chemistry. 86
A series of new 3-aminomethyl-4,11-dihydroxynaphtho[2,3- f ]indole-5,10-diones 6 – 13 bearing the cyclic diamine in the position 3 of the indole ring was synthesized. The majority of new compounds demonstrated a superior cytotoxicity than doxorubic