Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Vladimir I. Kashuba"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Heparan sulfate proteoglycans (HSPGs) regulate a wide range of biological activities in both physiological and pathological conditions. Altered expression or deregulated function of HSPGs and their heparan sulfate (HS) chains significantly contribute
Externí odkaz:
https://doaj.org/article/a7093514316b47049c443fc1a6b7bf6e
Autor:
Ganna V. Gerashchenko, Nataliya V. Hryshchenko, Nataliia S. Melnichuk, Tetiana V. Marchyshak, Serhii Yu Chernushyn, Irina V. Demchyshina, Ludmyla M. Chernenko, Igor V. Kuzin, Zenovii Yu Tkachuk, Vladimir I. Kashuba, Mykhailo A. Tukalo
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25618- (2024)
The aim: of our study was to identify and characterize the SARS-CoV-2 variants in COVID-19 patients’ samples collected from different regions of Ukraine to determine the relationship between SARS-CoV-2 phylogenetics and COVID-19 epidemiology. Patie
Externí odkaz:
https://doaj.org/article/03000d552b2c4ae4b95bf489b7dd4bd9
Autor:
S. Yu. Chernushyn, Nataliia Melnichuk, N. V. Hryshchenko, M. A. Tukalo, L. M. Chernenko, Vladimir I. Kashuba, T. V. Marchishak, V. K. Liashko, G. V. Gerashchenko, Z. Yu. Tkachuk
Publikováno v:
Biopolymers and Cell. 37:117-124
Aim. To identify and characterize the SARS-CoV-2 variants, collected upon the new wave of COVID-19 outbreak in Ivano-Frankivs’k region of Ukraine, using the whole genome genotyping. Methods. The parallel whole genome sequencing was performed on the
Publikováno v:
Biopolymers and Cell. 37:105-116
Autor:
O. A. Kononenko, Vladimir I. Kashuba, Yu. M. Bondarenko, G. V. Gerashchenko, E. O. Stakhovskyy, O. S. Mankovska, K. R. Cherniavskyi, A. S. Korsakova
Publikováno v:
Biopolymers and Cell. 37:23-32
Autor:
Maksymchuk Ov, Vladimir I. Kashuba
Publikováno v:
Pharmacological Reports. 72:1161-1172
Prostate cancer is the most common malignant disease among men. The signaling pathways, regulated by the androgen and vitamin D receptors, play a key role in prostate cancer. The intracellular level of androgens and vitamin D determines not only rece
Autor:
George Klein, Elena Kashuba, Vladimir I. Kashuba, Marie Arsenian-Henriksson, L M Kovalevska, Alexandra Abramsson, Suhas Darekar, Henrik Zetterberg, Muhammad Mushtaq
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We here describe the essential roles of RB and MRPS18-2 (S18-2) in homeostasis of cell stemness. Mouse primary cells expressing both S18-2 and RB (designated as RH18RB) exhibited a stem cell phenotype. As a proof of principle, we demonst
Publikováno v:
Ukrainian Biochemical Journal, Vol 92, Iss 1, Pp 5-11 (2020)
The interaction between malignant and stromal cells represents a major cross-talk pathway upon carcinogenesis. Cellular elements of the reactive tumor stroma are a heterogeneous population which are represented specifically by cancer-associated fibro
Autor:
Vitaly I Loginov, Alexey A Dmitriev, Vera N Senchenko, Irina V Pronina, Dmitry S Khodyrev, Anna V Kudryavtseva, George S Krasnov, Ganna V Gerashchenko, Larisa I Chashchina, Tatiana P Kazubskaya, Tatiana T Kondratieva, Michael I Lerman, Debora Angeloni, Eleonora A Braga, Vladimir I Kashuba
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0123369 (2015)
The SEMA3B gene is located in the 3p21.3 LUCA region, which is frequently affected in different types of cancer. The objective of our study was to expand our knowledge of the SEMA3B gene as a tumor suppressor and the mechanisms of its inactivation. I
Externí odkaz:
https://doaj.org/article/a619b4bbe46540769d31a45e40d81ecd
Autor:
G. V. Gerashchenko, E. O. Stakhovsky, Yu. Bondarenko, O. Mankovska, E. Rozenberg, Vladimir I. Kashuba, Olga Kononenko
Publikováno v:
Ukrainian Biochemical Journal, Vol 91, Iss 6, Pp 15-26 (2019)
Aurora kinases A and B play a crucial role in the regulation of mitosis, while Aurora C controls meiotic division. These proteins showed controversial behavior upon the development of epithelial tumors. Our aim was to examine if there are any differe