Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Vladimir G Fast"'
Autor:
Wesley LaBarge, Saidulu Mattapally, Ramaswamy Kannappan, Vladimir G Fast, Daniëlle Pretorius, Joel L Berry, Jianyi Zhang
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223424 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0219442.].
Externí odkaz:
https://doaj.org/article/4314de432294431799961d9e097797f7
Autor:
Wesley LaBarge, Saidulu Mattappally, Ramaswamy Kannappan, Vladimir G Fast, Daniëlle Pretorius, Joel L Berry, Jianyi Zhang
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219442 (2019)
Functional myocardium derived from human induced pluripotent stem cells (hiPSCs) can be impactful for cardiac disease modeling, drug testing, and the repair of injured myocardium. However, when hiPSCs are differentiated into cardiomyocytes, they do n
Externí odkaz:
https://doaj.org/article/223bee8b033940dc83f383bb64809d46
Autor:
Xi Lou, Yawen Tang, Lei Ye, Danielle Pretorius, Vladimir G Fast, Asher M Kahn-Krell, Jue Zhang, Jianhua Zhang, Aijun Qiao, Gangjian Qin, Timothy Kamp, James A Thomson, Jianyi Zhang
Publikováno v:
Cardiovascular Research. 119:1062-1076
Aims We have shown that human cardiac muscle patches (hCMPs) containing three different types of cardiac cells—cardiomyocytes (CMs), smooth muscle cells (SMCs), and endothelial cells (ECs), all of which were differentiated from human pluripotent st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab451db55c62dc817ee5d022df3f2aa
https://doi.org/10.1093/cvr/cvad004
https://doi.org/10.1093/cvr/cvad004
Autor:
Saidulu Mattapally, Kevin M. Pawlik, Vladimir G. Fast, Esther Zumaquero, Frances E. Lund, Troy D. Randall, Tim M. Townes, Jianyi Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 23 (2018)
Background We aim to generate a line of “universal donor” human induced pluripotent stem cells (hiPSCs) that are nonimmunogenic and, therefore, can be used to derive cell products suitable for allogeneic transplantation. Methods and Results hiPSC
Externí odkaz:
https://doaj.org/article/a327f67adb0a48f28f39de9cd732b010
Autor:
Yawen Tang, Sajesan Aryal, Xiaoxiao Geng, Xinyue Zhou, Vladimir G. Fast, Jianyi Zhang, Rui Lu, Yang Zhou
Publikováno v:
Circulation. 146(20)
Background: Direct cardiac reprogramming of fibroblasts into cardiomyocytes has emerged as a promising strategy to remuscularize injured myocardium. However, it is insufficient to generate functional induced cardiomyocytes from human fibroblasts usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a1a0d016eebd8a8438e6b130349052
https://pubmed.ncbi.nlm.nih.gov/36102189
https://pubmed.ncbi.nlm.nih.gov/36102189
Autor:
Saidulu Mattapally, Eric Zhang, Vladimir G Fast, Andrew E Pollard, Chandrakala Mattapally, Jianyi Zhang
Publikováno v:
Circulation. 144
Introduction: CRISPR editing of genomic regulatory elements with the intention of direct exon/intron splicing is a hopeful means of everlastingly alleviating genetic diseases. Cas9-induced DNA double-stranded break, non-homologous end-joining repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed4b110ce457e66d8a43fcef10e1d4b
https://doi.org/10.1161/circ.144.suppl_1.13426
https://doi.org/10.1161/circ.144.suppl_1.13426
Autor:
Asher Kahn-Krell, Danielle Pretorius, Jianfa Ou, Vladimir G. Fast, Silvio Litovsky, Joel Berry, Xiaoguang (Margaret) Liu, Jianyi Zhang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology
Human induced-pluripotent stem cells (hiPSCs) can be efficiently differentiated into cardiomyocytes (hiPSC-CMs) via the GiWi method, which uses small-molecule inhibitors of glycogen synthase kinase (GSK) and tankyrase to first activate and then suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a354d7006dee3bf901b59807f4c6de8e
https://doi.org/10.3389/fbioe.2021.674260
https://doi.org/10.3389/fbioe.2021.674260
Autor:
Mani T. Valarmathi, Vladimir G. Fast, Xi Lou, Wuqiang Zhu, Meng Zhao, Jianyi Zhang, Chengming Fan
Publikováno v:
Cardiovascular Research. 116:671-685
Aims In regenerative medicine, cellular cardiomyoplasty is one of the promising options for treating myocardial infarction (MI); however, the efficacy of such treatment has shown to be limited due to poor survival and/or functional integration of imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b81b0e1b14ba33711bb56f4cfae77b
https://doi.org/10.1093/cvr/cvz179
https://doi.org/10.1093/cvr/cvz179
Autor:
Timothy J. Kamp, Danielle Pretorius, Joel L. Berry, Vladimir G. Fast, Xi Lou, Jianyi Zhang, Asher Kahn-Krell
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Engineered cardiac tissues fabricated from human induced pluripotent stem cells (hiPSCs) show promise for ameliorating damage from myocardial infarction, while also restoring function to the damaged left ventricular (LV) myocardium. For these constru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08de687c7af877b107537218d8605b08
https://www.frontiersin.org/articles/10.3389/fcell.2021.670504/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.670504/full
Publikováno v:
Circulation Research. 127
Direct cardiac reprogramming to generate induced cardiomyocyte like cells (iCMs) from fibroblasts has emerged as a promising therapeutic strategy for the treatment of heart failure, which is still the leading cause of mortality and morbidity in devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::395b51763d1e840aeb8cbe844c3bd953
https://doi.org/10.1161/res.127.suppl_1.103
https://doi.org/10.1161/res.127.suppl_1.103