Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Vladimir E, Bondarenko"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C263-C291
Mouse models of heart failure are extensively used to research human cardiovascular diseases. In particular, one of the most common is the mouse model of heart failure resulting from transverse aortic constriction (TAC). Despite this, there are no co
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract A failing heart differs from healthy hearts by an array of symptomatic characteristics, including impaired Ca2+ transients, upregulation of Na+/Ca2+ exchanger function, reduction of Ca2+ uptake to sarcoplasmic reticulum, reduced K+ currents,
Externí odkaz:
https://doaj.org/article/f2173b0bd7394afe8e0a6efc5bf985f7
Publikováno v:
American journal of physiology. Cell physiology.
Mouse models of heart failure are extensively used to research human cardiovascular diseases. In particular, one of the most common is the mouse model of heart failure resulting from transverse aortic constriction (TAC). Despite this, there are no co
Autor:
Roman Y. Medvedev, Daniel G.P. Turner, Julia Gorelik, Francisco Alvarado, Vladimir E. Bondarenko, Alexey V. Glukhov
Publikováno v:
Biophysical Journal. 122:237a-238a
Autor:
Kelvin Rozier, Vladimir E. Bondarenko
Publikováno v:
International Journal of Bifurcation and Chaos. 32
Hopfield neural network attracts particular attention as it serves as a relatively simple mathematical model that describes some properties of the brain function. We investigate analog Hopfield neural networks with two time delays. It is shown that t
Publikováno v:
Am J Physiol Heart Circ Physiol
Various experimental mouse models are extensively used to research human diseases, including atrial fibrillation, the most common cardiac rhythm disorder. Despite this, there are no comprehensive mathematical models that describe the complex behavior
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 318:H264-H282
The β1-adrenergic regulation of cardiac myocyte contraction plays an important role in regulating heart function. Activation of this system leads to an increased heart rate and stronger myocyte contraction. However, chronic stimulation of the β1-ad
Publikováno v:
The Journal of Membrane Biology. 252:77-103
Sodium ion channel is a membrane protein that plays an important role in excitable cells, as it is responsible for the initiation of action potentials. Understanding the electrical characteristics of sodium channels is essential in predicting their b
Autor:
Vladimir E Bondarenko
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89113 (2014)
The β1-adrenergic signaling system plays an important role in the functioning of cardiac cells. Experimental data shows that the activation of this system produces inotropy, lusitropy, and chronotropy in the heart, such as increased magnitude and re
Externí odkaz:
https://doaj.org/article/0cd0703777db4b6c984396d7c55fc49c
Autor:
Paula D Mullins, Vladimir E Bondarenko
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63141 (2013)
Mathematical models of cardiac function at the cellular level include three major components, such as electrical activity, Ca(2+) dynamics, and cellular shortening. We developed a model for mouse ventricular myocyte contraction which is based on our
Externí odkaz:
https://doaj.org/article/e0e1994127cd41ffb08333e2704c1551