Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Vladimir Chekhonin"'
Autor:
Olga Abramova, Yana Zorkina, Konstantin Pavlov, Valeria Ushakova, Anna Morozova, Eugene Zubkov, Olga Pavlova, Zinaida Storozheva, Olga Gurina, Vladimir Chekhonin
Publikováno v:
Neural Plasticity, Vol 2024 (2024)
Prenatal stress (PS) affects the development and functioning of the central nervous system, but the exact mechanisms underpinning this effect have not been pinpointed yet. A promising model of PS is one based on chronic exposure of pregnant rodents t
Externí odkaz:
https://doaj.org/article/9e0a887e72064639a3861848791d356e
Autor:
Elvira Cherkashova, Daria Namestnikova, Georgiy Leonov, Ilya Gubskiy, Kirill Sukhinich, Pavel Melnikov, Vladimir Chekhonin, Konstantin Yarygin, Dmitry Goldshtein, Diana Salikhova
Publikováno v:
PeerJ, Vol 11, p e16358 (2023)
Background Cell therapy using neural progenitor cells (NPCs) is a promising approach for ischemic stroke treatment according to the results of multiple preclinical studies in animal stroke models. In the vast majority of conducted animal studies, the
Externí odkaz:
https://doaj.org/article/e1346cf8177a41e397dad094e282ced9
Autor:
Olga Abramova, Yana Zorkina, Valeriya Ushakova, Dmitry Gryadunov, Anna Ikonnikova, Elena Fedoseeva, Marina Emelyanova, Aleksandra Ochneva, Irina Morozova, Konstantin Pavlov, Timur Syunyakov, Alisa Andryushchenko, Victor Savilov, Marat Kurmishev, Denis Andreuyk, Svetlana Shport, Olga Gurina, Vladimir Chekhonin, Georgy Kostyuk, Anna Morozova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13395 (2023)
Many studies aim to detect the early phase of dementia. One of the major ways to achieve this is to identify corresponding biomarkers, particularly immune blood biomarkers. The objective of this study was to identify such biomarkers in patients with
Externí odkaz:
https://doaj.org/article/164b5ead171c422fa9b2d5d6ba7e651a
Autor:
Tatiana Abakumova, Anastasia Kuzkina, Philipp Koshkin, Daria Pozdeeva, Maxim Abakumov, Pavel Melnikov, Klavdia Ionova, Ilia Gubskii, Olga Gurina, Natalia Nukolova, Vladimir Chekhonin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12688 (2023)
The development of new neurotherapeutics depends on appropriate animal models being chosen in preclinical studies. The cuprizone model is an effective tool for studying demyelination and remyelination processes in the brain, but blood–brain barrier
Externí odkaz:
https://doaj.org/article/c11172e1f7384b04a33d86cacac79f5a
Autor:
Eugene Zubkov, Olga Abramova, Yana Zorkina, Aleksandra Ochneva, Valeria Ushakova, Anna Morozova, Olga Gurina, Alexander Majouga, Vladimir Chekhonin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objectives: In the current study, we compared the effects of a single intranasal administration of clomipramine with effects of four neuropeptides, melatonin, oxytocin, orexin, and neuropeptide Y, to compare them in an acute stress model.Methods: The
Externí odkaz:
https://doaj.org/article/0e56c1e11cad46d48e35d87c83cb918d
Autor:
Julia Malinovskaya, Rawan Salami, Marat Valikhov, Veronika Vadekhina, Aleksey Semyonkin, Alevtina Semkina, Maxim Abakumov, Yifat Harel, Esthy Levy, Tzuriel Levin, Rachel Persky, Vladimir Chekhonin, Jean-Paul Lellouche, Pavel Melnikov, Svetlana Gelperina
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 627 (2022)
Predicting the ability of nanoparticles (NP) to access the tumor is key to the success of chemotherapy using nanotherapeutics. In the present study, the ability of the dual NP-based theranostic system to accumulate in the tumor was evaluated in vivo
Externí odkaz:
https://doaj.org/article/18ac6e1daa2745c4bd1814b6fbc65778
Autor:
Aleksandra Ochneva, Yana Zorkina, Olga Abramova, Olga Pavlova, Valeriya Ushakova, Anna Morozova, Eugene Zubkov, Konstantin Pavlov, Olga Gurina, Vladimir Chekhonin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14498 (2022)
Mental disorders represent common brain diseases characterized by substantial impairments of social and cognitive functions. The neurobiological causes and mechanisms of psychopathologies still have not been definitively determined. Various forms of
Externí odkaz:
https://doaj.org/article/0ec4ea75436e4ee0a04432245802cc08
Autor:
Yana Zorkina, Timur Syunyakov, Olga Abramova, Alisa Andryushchenko, Denis Andreuyk, Evgeniya Abbazova, Dmitry Goncharov, Alisa Rakova, Nika Andriushchenko, Dmitry Gryadunov, Anna Ikonnikova, Elena Fedoseeva, Marina Emelyanova, Kristina Soloveva, Konstantin Pavlov, Olga Karpenko, Victor Savilov, Marat Kurmishev, Olga Gurina, Vladimir Chekhonin, Georgy Kostyuk, Anna Morozova
Publikováno v:
Diagnostics, Vol 12, Iss 10, p 2312 (2022)
(1) Background: Older people suffer from cognitive decline; several risk factors contribute to greater cognitive decline. We used acquired (COVID-19 infection) and non-modifiable (presence of APOE rs429358 and rs7412 polymorphisms) factors to study t
Externí odkaz:
https://doaj.org/article/4454692bfb69487698c6fc0c43f92799
Autor:
Nika Andriushchenko, Kira Nebogina, Yana Zorkina, Olga Abramova, Eugene Zubkov, Aleksandra Ochneva, Valeria Ushakova, Konstantin Pavlov, Olga Gurina, Vladimir Chekhonin, Anna Morozova
Publikováno v:
Scientia Pharmaceutica, Vol 90, Iss 3, p 50 (2022)
The search for potential effective antidepressants with minimal side effects is necessary. Peptides are possible applicants for this role. We investigated the antidepressant effect of neuropeptide Y (NY), alone and in combination with clomipramine, i
Externí odkaz:
https://doaj.org/article/803ab93d897e4c158f28445cf037d425
Autor:
Anna Morozova, Yana Zorkina, Konstantine Pavlov, Olga Pavlova, Olga Abramova, Valeria Ushakova, Alexander V. Mudrak, Svetlana Zozulya, Irina Otman, Zoya Sarmanova, Tatiana Klyushnik, Alexander Reznik, Georgiy Kostyuk, Vladimir Chekhonin
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
We investigated the associations of DRD3 rs6280, HTR1A rs6295, BDNF rs6265, SCL6A4 rs16965628, and 5HT2A rs7322347 with schizophrenia in a case–control study, and associations of these genetic variants with several clinical features. We also invest
Externí odkaz:
https://doaj.org/article/d029231dcf5c40c7a1f1cd896e29c51b