Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Vladimir B. Serikov"'
Publikováno v:
Stem Cells and Development. 21:589-597
Proteins p130 and E2f4, members of the retinoblastoma protein (pRb) family/E2F transcription factor family, are the key elements in regulation of cell cycle and differentiation. The functional role of the p130/E2f4 in mesenchymal stem cells (MSC) is
Autor:
Jae-Woo Lee, Vladimir B. Serikov, Xiaohui Fang, Naveen Gupta, Yuanlin Song, Michael A. Matthay, Anna Krasnodembskaya
Publikováno v:
Stem Cells. 28:2229-2238
Recent in vivo studies indicate that mesenchymal stem cells (MSCs) may have beneficial effects in the treatment of sepsis induced by bacterial infection. Administration of MSCs in these studies improved survival and enhanced bacterial clearance. The
Autor:
Hirokazu Ikeda, Mark C. Walters, Sandra Larkin, Vladimir B. Serikov, William Green, Frans A. Kuypers, Catherine Hounshell
Publikováno v:
Experimental Biology and Medicine. 234:813-823
The main barrier to a broader clinical application of umbilical cord blood (UCB) transplantation is its limiting cellular content. Thus, the discovery of hematopoietic progenitor cells in murine placental tissue led us investigate whether the human p
Autor:
Nikolai V. Tomilin, Vladimir B. Serikov, L. V. Solovjeva, Nadezhda Pleskach, Denis Firsanov, Maria Svetlova
Publikováno v:
Radiation Research. 171:419-424
Forskolin is a natural compound found in the coleus herb that activates the enzyme adenylate cyclase and increases the concentration of intracellular cyclic AMP (cAMP). This chemical is widely used as a stimulating food additive. It is unknown whethe
Publikováno v:
FEBS Journal. 274:5804-5814
Peroxiredoxin V (PRDX5) is a member of the family of mammalian proteins that neutralize reactive oxygen species. The PRDX5 gene is constitutively expressed at a high level in many human tissues, but functional elements of its promoter responsible for
Autor:
Vladimir I. Bashkirov, Alexandra Smirnova, Jung H. Suh, Vladimir B. Serikov, Boris Zhivotovsky, Andrey Kropotov, Nikolai V. Tomilin
Publikováno v:
FEBS Journal. 273:2607-2617
Peroxiredoxins belong to a family of antioxidant proteins that neutralize reactive oxygen species. One member of this family, peroxiredoxin I (PRDX1), suppresses DNA oxidation. Peroxiredoxin V (PRDX5) has been cloned as a transcriptional corepressor,
Publikováno v:
Biochemical and Biophysical Research Communications. 336:762-769
During G0 phase the p130, member of the pRb tumor suppressor protein family, forms a repressor complex with E2F4 which is inactivated in G1/S by hyperphosphorylation of the p130. The role of p130 after G1/S remains poorly investigated. We found that
Publikováno v:
European Journal of Applied Physiology. 91:314-323
To investigate the relative role of pulmonary perfusion compared to ventilation on lung heat exchange, we determined the effects of blood flow, tidal volume and frequency of ventilation on the rate of lung heat transfer. In anesthetized dogs and isol
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 30:261-270
The goal of this study was to determine whether the extracellular regulated kinases (ERK1/2) are involved in leukocyte transmigration across airway epithelium and the associated changes in epithelial permeability. In vitro, we used formyl-methionyl-l
Autor:
Norman C. Staub, Neal Fleming, E. H. Jerome, Vladimir B. Serikov, T. V. Glazanova, Haruki Higashimori
Publikováno v:
Inflammation. 27:175-190
We have previously demonstrated that the detergent Tyloxapol is effective in preventing reactions to endotoxin. We studied the effects of Tyloxapol on the morbidity and mortality from endotoxemia in rabbits and on the mortality in rats with sepsis. T