Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Vladimir B. Ritov"'
Publikováno v:
Hypertension
Here, we tested the hypothesis that TNAP (tissue nonspecific alkaline phosphatase) modulates vascular responsiveness to norepinephrine. In the isolated, Tyrode’s-perfused rat mesentery, 50 µmol/L of L-p-bromotetramisole (L-p-BT; selective TNAP inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c38496bdcc7f29e418580a969a1d40c
https://doi.org/10.1161/hypertensionaha.120.15822
https://doi.org/10.1161/hypertensionaha.120.15822
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 382(2)
8-Aminoguanine and 8-aminoguanosine (via metabolism to 8-aminoguanine) are endogenous 8-aminopurines that induce diuresis, natriuresis, and glucosuria by inhibiting purine nucleoside phosphorylase (PNPase); moreover, both 8-aminopurines cause antikal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecd00c9cacda0eb4527f2ec72be5a9d
https://pubmed.ncbi.nlm.nih.gov/35609923
https://pubmed.ncbi.nlm.nih.gov/35609923
Autor:
Edwin K, Jackson, Elizabeth V, Menshikova, Vladimir B, Ritov, Delbert G, Gillespie, Zaichuan, Mi
Publikováno v:
Biochem Pharmacol
BACKGROUND. 8-Aminoguanine exerts natriuretic and antihypertensive activity. Whether and how “free” 8-aminoguanine exists in vivo is unclear. Because 8-nitroguanosine is naturally occurring, we tested the hypothesis that 8-aminoguanine can arise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3cf8eca35c8791c5ecd6dc00cf22096
https://doi.org/10.1016/j.bcp.2022.115076
https://doi.org/10.1016/j.bcp.2022.115076
Autor:
Annabel A Ferguson, Sudipa Roy, Kaitlyn N Kormanik, Yongsoon Kim, Kathleen J Dumas, Vladimir B Ritov, Dietrich Matern, Patrick J Hu, Alfred L Fisher
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004020 (2013)
Recent work has identified changes in the metabolism of the aromatic amino acid tyrosine as a risk factor for diabetes and a contributor to the development of liver cancer. While these findings could suggest a role for tyrosine as a direct regulator
Externí odkaz:
https://doaj.org/article/e80bd8e6faa045ac90bf2098b2e3ed86
Publikováno v:
Hypertension. 72:909-917
SDF-1α (stromal cell–derived factor-1α) is a CXCR4-receptor agonist and DPP4 (dipeptidyl peptidase 4) substrate. SDF-1α, particularly when combined with sitagliptin to block the metabolism of SDF-1α by DPP4, stimulates proliferation of cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ece59014a94bf6bf7ab80c55448d88d
https://doi.org/10.1161/hypertensionaha.118.11666
https://doi.org/10.1161/hypertensionaha.118.11666
Autor:
Catherine J. Baty, Megan L. Eshbach, Ora A. Weisz, Youssef Rbaibi, Yu Jiang, Katherine E. Shipman, Elizabeth V. Menshikova, Edwin K. Jackson, Kimberly R. Long, Vladimir B. Ritov
Publikováno v:
Molecular Biology of the Cell
Kidney proximal tubule cells cultured under shear stress become remarkably well differentiated and endocytic capacity is rapidly tuned in response to acute changes in shear stress. The results have implications for understanding how proximal tubule f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccebbc1f5797bed830bedeb15c5e2b9
https://doi.org/10.1091/mbc.e17-04-0211
https://doi.org/10.1091/mbc.e17-04-0211
Autor:
Elizabeth M. Kenny, Catherine Gretchen, Mahesh Sharma, Clifton W. Callaway, Hülya Bayır, Melita Viegas, Valerian E. Kagan, Patrick M. Kochanek, Vladimir B. Ritov, Nahmah Kim-Campbell, Goundappa K. Balasubramani
Publikováno v:
Pediatr Crit Care Med
To determine the production of 9-hydroxyoctadecadienoic acid and 13-hydroxyoctadecadienoic acid during cardiopulmonary bypass in infants and children undergoing cardiac surgery, evaluate their relationship with increase in cell-free plasma hemoglobin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac0f74c79de69d3cae26a52d0607ccd
https://pubmed.ncbi.nlm.nih.gov/31305328
https://pubmed.ncbi.nlm.nih.gov/31305328
Autor:
Vladimir A. Tyurin, Joel S. Greenberger, Vladimir B. Ritov, Marcus Conrad, Tamil S. Anthonymuthu, Yulia Y. Tyurina, Andrew A. Amoscato, Brent R. Stockwell, Jianfei Jiang, José Pedro Friedmann Angeli, Simon C. Watkins, Judith Klein-Seetharaman, Dariush Mohammadyani, Valerian E. Kagan, Gaowei Mao, Ivet Bahar, Sebastian Doll, Hülya Bayır, Qin Yang, Haider H. Dar, Alexandr A. Kapralov, Rama K. Mallampalli, Feng Qu, Claudette M. St. Croix, Bing Liu, Bettina Proneth
Publikováno v:
Nature Chemical Biology. 13:81-90
Enigmatic lipid peroxidation products have been claimed as the proximate executioners of ferroptosis-a specialized death program triggered by insufficiency of glutathione peroxidase 4 (GPX4). Using quantitative redox lipidomics, reverse genetics, bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b56ad72aa33ff2fc4f3c168153b0a55
https://doi.org/10.1038/nchembio.2238
https://doi.org/10.1038/nchembio.2238
Autor:
Vladimir B. Ritov, Paul M. Coen, Gabriele Schoiswohl, Giovanna Distefano, Noah P. Gardner, Mahesh K. Basantani, Rudolf Zechner, Cynthia F. Yazbeck, Lingzhi Cai, Erin E. Kershaw, Petra C. Kienesberger, Mitchell Sitnick, Donna B. Stolz, James P. DeLany, Bret H. Goodpaster, Renate Schreiber, Thomas Pulinilkunnil
Publikováno v:
Diabetes
Intramyocellular triacylglycerol (IMTG) accumulation is highly associated with insulin resistance and metabolic complications of obesity (lipotoxicity), whereas comparable IMTG accumulation in endurance-trained athletes is associated with insulin sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffde55f1af9806d81ced22442d6e5a0
https://doi.org/10.2337/db13-0500
https://doi.org/10.2337/db13-0500
Autor:
Maja Stefanovic-Racic, John J. Dubé, Vladimir B. Ritov, Elizaveta V. Menshikova, E.M. Leachman, Paul M. Coen, Frederico G.S. Toledo, Kazanna C. Hames, Bret H. Goodpaster, James P. DeLany
Publikováno v:
Obesity. 21:2362-2371
Objective The link between a reduced capacity for skeletal muscle mitochondrial fatty acid oxidation (FAO) and lipotoxicity in human insulin resistance has been the subject of intense debate. The objective of this study was to investigate whether red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af20d8ceb696bd81f84de503c6e645a0
https://doi.org/10.1002/oby.20381
https://doi.org/10.1002/oby.20381