Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Vladimir A. Lizunov"'
Autor:
Vladimir A Lizunov, Karin G Stenkula, Paul S Blank, Aaron Troy, Jo-Ping Lee, Monica C Skarulis, Samuel W Cushman, Joshua Zimmerberg
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119291 (2015)
While intercellular communication processes are frequently characterized by switch-like transitions, the endocrine system, including the adipose tissue response to insulin, has been characterized by graded responses. Yet here individual cells from ad
Externí odkaz:
https://doaj.org/article/1e1e9dc6c25b42e5a36f4f9e327f68ea
Autor:
Georgeta Crivat, Vladimir A Lizunov, Caroline R Li, Karin G Stenkula, Joshua Zimmerberg, Samuel W Cushman, Leslie Pick
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e77953 (2013)
The fruit fly Drosophila melanogaster is an excellent model system for studies of genes controlling development and disease. However, its applicability to physiological systems is less clear because of metabolic differences between insects and mammal
Externí odkaz:
https://doaj.org/article/318f31fbc7834aa38afafeb7cb206ed4
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57559 (2013)
Insulin-stimulated delivery of glucose transporter-4 (GLUT4) to the plasma membrane (PM) is the hallmark of glucose metabolism. In this study we examined insulin's effects on GLUT4 organization in PM of adipose cells by direct microscopic observation
Externí odkaz:
https://doaj.org/article/5942b6b611b546c6b2ca6d2c8354c9a7
Publikováno v:
Vestnik Tomskogo gosudarstvennogo universiteta. Istoriya. :59-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39f8478c75240fc4ca3d731de1585f03
https://doi.org/10.17223/19988613/34/10
https://doi.org/10.17223/19988613/34/10
Autor:
Sergey M. Bezrukov, Leonardo Dagdug, Alexander M. Berezhkovskii, Vladimir A. Lizunov, Joshua Zimmerberg
Publikováno v:
Biophysical Journal. 106:500-509
Various membrane functional units such as receptors, transporters, and channels, whose action necessarily involves capturing diffusing molecules, are often organized into multimeric complexes forming clusters on the cell and organelle membranes. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b157bb16f4e5dcf84d12e9199889063b
https://doi.org/10.1016/j.bpj.2013.12.015
https://doi.org/10.1016/j.bpj.2013.12.015
Autor:
Samuel W. Cushman, Jo-Ping Lee, Monica C. Skarulis, Karin G. Stenkula, Joshua Zimmerberg, Vladimir A. Lizunov
Publikováno v:
Diabetes
Systemic glucose homeostasis is profoundly influenced by adipose cell function. Here we investigated GLUT4 dynamics in living adipose cells from human subjects with varying BMI and insulin sensitivity index (Si) values. Cells were transfected with he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1960f5c716a5a48e433dde55ae480bb6
https://doi.org/10.2337/db12-1741
https://doi.org/10.2337/db12-1741
Autor:
Leonid V. Chernomordik, Kamran Melikov, Bokkee Eun, Santosh Kumar Verma, Claudia Gebert, Evgenia Leikina, Michael M. Kozlov, Vladimir A. Lizunov, Karl Pfeifer, Sarmistha Sanyal
Publikováno v:
The Journal of Cell Biology
Annexins A1 and A5 are important for initial lipid mixing, whereas subsequent stages of myoblast fusion depend on dynamin, phosphatidylinositol(4,5)bisphosphate, and cellular metabolism.
Myoblast fusion into multinucleated myotubes is a crucial
Myoblast fusion into multinucleated myotubes is a crucial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0d268d2b2c60abfbda5e963ac09daa
http://europepmc.org/articles/PMC3542790
http://europepmc.org/articles/PMC3542790
Publikováno v:
Cell Metabolism. 12(3):250-259
While the glucose transporter-4 (GLUT4) is fundamental to insulin-regulated glucose metabolism, its dynamic spatial organization in the plasma membrane (PM) is unclear. Here, using multicolor TIRF microscopy in transfected adipose cells, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16c06653fb3bfcdeac709fe27e1b385
Autor:
Vladimir A. Lizunov, Samuel W. Cushman, Ivonne Lisinski, Karin G. Stenkula, Joshua Zimmerberg
Publikováno v:
Journal of Biological Chemistry. 284:7914-7919
Insulin regulates cellular glucose uptake by changing the amount of glucose transporter-4 (GLUT4) in the plasma membrane through stimulation of GLUT4 exocytosis. However, how the particular trafficking, tethering, and fusion steps are regulated by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d70a28440081d5c2d1ebd0bb2d0d2a4
https://doi.org/10.1074/jbc.m806460200
https://doi.org/10.1074/jbc.m806460200
Autor:
Vladimir A. Lizunov, Samuel W. Cushman, Geoffrey D. Holman, Daniel J. Fazakerley, Scott P. Lawrence
Publikováno v:
Journal of Cell Science. 122:727-734
A new mouse model has been developed to study the localisation and trafficking of the glucose transporter GLUT4 in muscle. The mouse line has specific expression of a GFP and HA-epitope-tagged version of GLUT4 under the control of a muscle-specific p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565ae6a273be70598fffa7894109ce18
https://doi.org/10.1242/jcs.041178
https://doi.org/10.1242/jcs.041178