Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vladimir A. Ledov"'
A Pentavalent Shigella flexneri LPS-Based Vaccine Candidate Is Safe and Immunogenic in Animal Models
Autor:
Vladimir A. Ledov, Marina E. Golovina, Biana I. Alkhazova, Vyacheslav L. Lvov, Alexander L. Kovalchuk, Petr G. Aparin
Publikováno v:
Vaccines, Vol 11, Iss 2, p 345 (2023)
A multivalent vaccine is much needed to achieve protection against predominant Shigella serotypes. Recently, we demonstrated the clinical applicability and immunogenic potential of tri-acylated S. flexneri 2a lipopolysaccharide (Ac3-S-LPS). Using a s
Externí odkaz:
https://doaj.org/article/64240cfa51ae4315a0e191fd316d5475
Autor:
Vladimir A. Ledov
Publikováno v:
Clinical Microbiology and Antimicrobial Chemotherapy. 23:400-403
Objective. To determine functional anti-LPS specific serum bactericidal antibody (SBA) and opsonophagocytic killing antibody (OPKA) activities in mice immunized with a pentavalent candidate vaccine against Shigella flexneri 1b, 2a, 3a, 6, Y (PF). Mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91abb2d45f3a9b2841d39c1b727bd4a5
https://doi.org/10.36488/cmac.2021.4.400-403
https://doi.org/10.36488/cmac.2021.4.400-403
Autor:
Vyacheslav L. L'vov, Marina Eduardovna Golovina, Anna Aleksandrovna Markina, Vladimir A. Ledov, Alexander L. Kovalchuk, Yuriy A. Knirel, Petr G. Aparin
Publikováno v:
Vaccine. 37:1062-1072
Shigellosis, a major cause of diarrhea worldwide, exhibits high morbidity and mortality in children. Specificity of Shigella immunity is determined by the structure of the main protective O-antigen polysaccharide component incorporated into the lipop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc36ee77fc1ddbba4cd3690f13fb5d5
https://doi.org/10.1016/j.vaccine.2018.12.067
https://doi.org/10.1016/j.vaccine.2018.12.067
Autor:
Alexander S. Shashkov, Petr G. Aparin, Vladimir A. Ledov, Sergei D. Shevelev, Maria Evgen'evna Shekht, Lu Feng, Sof'ya N. Senchenkova, Andrei V. Perepelov, Bin Liu, Vyacheslav L. L'vov, Lei Wang, Yuriy A. Knirel
Publikováno v:
FEMS immunology and medical microbiology. 66(2)
Shigella flexneri is an important human pathogen causing shigellosis. Strains of S. flexneri are serologically heterogeneous and, based on O-antigens, are currently classified into 14 types. Structures of the O-antigens (O-polysaccharides) of S. flex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ab206974ac0148e86f2b6c18020011
https://pubmed.ncbi.nlm.nih.gov/22724405
https://pubmed.ncbi.nlm.nih.gov/22724405