Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vladimir, Rotrekl"'
Autor:
Gabin de La Bourdonnaye, Tereza Ghazalova, Petr Fojtik, Katerina Kutalkova, David Bednar, Jiri Damborsky, Vladimir Rotrekl, Veronika Stepankova, Radka Chaloupkova
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 942-951 (2024)
FGF21 is an endocrine signaling protein belonging to the family of fibroblast growth factors (FGFs). It has emerged as a molecule of interest for treating various metabolic diseases due to its role in regulating glucogenesis and ketogenesis in the li
Externí odkaz:
https://doaj.org/article/dfa7bab639fc453cbad54a637e1e360f
Autor:
Martin Pesl, Sarka Jelinkova, Guido Caluori, Maria Holicka, Jan Krejci, Petr Nemec, Aneta Kohutova, Vita Zampachova, Petr Dvorak, Vladimir Rotrekl
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract We describe the association of Becker muscular dystrophy (BMD) derived heart failure with the impairment of tissue homeostasis and remodeling capabilities of the affected heart tissue. We report that BMD heart failure is associated with a si
Externí odkaz:
https://doaj.org/article/e39e2d7c174f4093896d0a2cd8c420b2
Autor:
Simon Klimovic, Martin Scurek, Martin Pesl, Deborah Beckerova, Sarka Jelinkova, Tomas Urban, Daniil Kabanov, Zdenek Starek, Marketa Bebarova, Jan Pribyl, Vladimir Rotrekl, Kristian Brat
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Cardiac side effects of some pulmonary drugs are observed in clinical practice. Aminophylline, a methylxanthine bronchodilator with documented proarrhythmic action, may serve as an example. Data on the action of aminophylline on cardiac cell electrop
Externí odkaz:
https://doaj.org/article/7df63e2188814610ad3c7fe31adc71f2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Mild hypoxia (5% O2) as well as FGFR1-induced activation of phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B (PI3K/AKT) and MAPK signaling pathways markedly support pluripotency in human pluripotent stem cells (hPSCs). This study demon
Externí odkaz:
https://doaj.org/article/1d901a492538423d99fa85f6f30bfeda
Autor:
Guido Caluori, Eva Odehnalova, Tomasz Jadczyk, Martin Pesl, Iveta Pavlova, Lucia Valikova, Steffen Holzinger, Veronika Novotna, Vladimir Rotrekl, Ales Hampl, Michal Crha, Dalibor Cervinka, Zdenek Starek
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
IntroductionPulsed field ablation (PFA) exploits the delivery of short high-voltage shocks to induce cells death via irreversible electroporation. The therapy offers a potential paradigm shift for catheter ablation of cardiac arrhythmia. We designed
Externí odkaz:
https://doaj.org/article/97440b9d2b2743cd9bc3f37e02e628f8
Autor:
Sarka Jelinkova, Aleksandra Vilotic, Jan Pribyl, Franck Aimond, Anton Salykin, Ivana Acimovic, Martin Pesl, Guido Caluori, Simon Klimovic, Tomas Urban, Hana Dobrovolna, Vladimir Soska, Petr Skladal, Alain Lacampagne, Petr Dvorak, Albano C. Meli, Vladimir Rotrekl
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Duchenne muscular dystrophy (DMD) is a severe genetic disorder characterized by the lack of functional dystrophin. DMD is associated with progressive dilated cardiomyopathy, eventually leading to heart failure as the main cause of death in DMD patien
Externí odkaz:
https://doaj.org/article/894acdf8147b4845b5659a63c9f195eb
Autor:
Sarka Jelinkova, Lenka Markova, Martin Pesl, Iveta Valáškova, Eva Makaturová, Lenka Jurikova, Petr Vondracek, Alain Lacampagne, Petr Dvorak, Albano C. Meli, Vladimir Rotrekl
Publikováno v:
Stem Cell Research, Vol 40, Iss , Pp - (2019)
Duchenne muscular dystrophy (DMD) affects 1:3500–5000 newborn boys and manifests with progressive skeletal muscle wasting, respiratory failure and eventual heart failure. Symptoms show different onset from patients' childhood to the second decade o
Externí odkaz:
https://doaj.org/article/cdd3609ab2de48e98c2cf4a95cd1e333
Autor:
Sarka Jelinkova, Yvonne Sleiman, Petr Fojtík, Franck Aimond, Amanda Finan, Gerald Hugon, Valerie Scheuermann, Deborah Beckerová, Olivier Cazorla, Marie Vincenti, Pascal Amedro, Sylvain Richard, Josef Jaros, Petr Dvorak, Alain Lacampagne, Gilles Carnac, Vladimir Rotrekl, Albano C. Meli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 5025 (2021)
Duchenne muscular dystrophy (DMD) is a devastating condition shortening the lifespan of young men. DMD patients suffer from age-related dilated cardiomyopathy (DCM) that leads to heart failure. Several molecular mechanisms leading to cardiomyocyte de
Externí odkaz:
https://doaj.org/article/f77b0ad1eb374f42a3c3b2ffb803ec46
Autor:
Monia Souidi, Yvonne Sleiman, Ivana Acimovic, Jan Pribyl, Azzouz Charrabi, Volker Baecker, Valerie Scheuermann, Martin Pesl, Sarka Jelinkova, Petr Skladal, Petr Dvorak, Alain Lacampagne, Vladimir Rotrekl, Albano C. Meli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 662 (2021)
Numerous protocols of cardiac differentiation have been established by essentially focusing on specific growth factors on human pluripotent stem cell (hPSC) differentiation efficiency. However, the optimal environmental factors to obtain cardiac myoc
Externí odkaz:
https://doaj.org/article/805299a630e143abb10d726383edcbf9
Autor:
Martin Pesl, Jan Pribyl, Petr Dvorak, Zdenek Starek, Petr Skladal, Kristian Brat, Vladimir Rotrekl
Publikováno v:
Biomedical Applications ISBN: 9783110989380
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc0aec4862e964a3ba2207235a9a2b0
https://doi.org/10.1515/9783110989380-011
https://doi.org/10.1515/9783110989380-011
