Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Vladimir, Iani"'
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 126:11-16
Folate is essential for cell division and growth. Deficiency is linked to birth defects, magaloblastic anaemia, cardiovascular disease, etc. Folic acid is a synthetic form of folate and is used to fortify food and in supplements. In aqueous solutions
Publikováno v:
Anticancer research. 36(3)
Most studies have demonstrated that sunscreens with lower sun protection factor (SPF) do not prevent the production of vitamin D because much lower amount of sunscreen (SPF30) is applied than recommended (2 mg/cm(2)) indicating that a significant amo
Publikováno v:
Scopus-Elsevier
This study investigated photobleaching of protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (ALA) and ALA-heptyl ester during superficial photodynamic therapy (PDT) in normal skin of the female BALB/c-nu/nu athymic mouse. We examined the effe
Publikováno v:
Photodiagnosis and Photodynamic Therapy. 7:239-245
Summary Background Measurements of tissue oxygenation and blood supply are of vital importance during photodynamic therapy. The aim of this study was to measure photosensitization responses in healthy mouse skin using non-invasive reflectance spectro
Autor:
Desmond I. J. Morrow, Vladimir Iani, Asta Juzeniene, Johan Emelian Moan, Ryan F. Donnelly, Patrycja Mikolajewska, Thakur Raghu Raj Singh, Martin J. Garland
Publikováno v:
Pharmaceutical Research. 27:2213-2220
To determine the impact of skin pretreatment with microneedles (MNs) on ALA- and MAL-induced protoporphyrin IX (PpIX) production, as well as MN impact on pain sensations during light exposure and erythema after PDT.The skin of 14 healthy volunteers w
Autor:
Paul A. McCarron, Ryan F. Donnelly, Asta Juzeniene, Petras Juzenas, A. David Woolfson, Vladimir Iani, Rasil Al-Kassas, Johan Emelian Moan
Publikováno v:
Biopharmaceutics & Drug Disposition. 30:55-70
A novel 5-aminolevulinic acid (ALA)-containing microparticulate system was produced recently, based on incorporation of ALA into particles prepared from a suppository base that maintains drug stability during storage and melts at skin temperature to
Publikováno v:
Photochemistry and Photobiology. 76:320-328
Hypericin is a promising photosensitizer for photodynamic therapy (PDT) characterized by a high yield of singlet oxygen. Photobleaching of hypericin has been studied by means of absorption and fluorescence spectroscopy in different biological systems
Autor:
Petras Juzenas, Vladimir Iani, Miron Kaliszewski, Alfreda Graczyk, Patrycja Mikolajewska, Johan Emelian Moan, Asta Juzeniene, Li Wei Ma, Miroslaw Kwasny
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 87:67-72
5-Aminolevulinic acid (ALA) is a natural precursor of protoporphyrin IX (PpIX) and heme in cells. Photodynamic therapy (PDT) utilizes a metabolic imbalance in cancer cells, leading to increased PpIX generation from exogenous ALA. Due to chemical inst
Publikováno v:
Photochemistry and Photobiology. 76:452-456
Significant amounts of protoporphyrin IX (PpIX) are formed after 6 min of topical application of 5-aminolevulinic acid (ALA) and its hexylester derivative, whereas PpIX is formed after 10 min of topical application of ALA-methylester derivative in no
Publikováno v:
Journal of Environmental Pathology, Toxicology and Oncology. 26:165-172
Melanotic melanomas have a poor response to photodynamic therapy (PDT). The reason for this is that melanin absorbs light over the entire wavelength region used for PDT (400-750 nm). Photobleaching of melanin is an approach to overcome this obstacle.