Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Vladimir, Bilim"'
Autor:
Masaki Murata, Vladimir Bilim, Yuko Shirono, Akira Kazama, Kaede Hiruma, Masayuki Tasaki, Yoshihiko Tomita
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 9, Pp 7432-7448 (2023)
The prognosis of patients with advanced renal cell carcinoma (RCC) has improved with newer therapies, including molecular-targeted therapies and immuno-oncology agents. Despite these therapeutic advances, many patients with metastatic disease remain
Externí odkaz:
https://doaj.org/article/9ac6ea5ad56e4068bf42bd8b1f8af74a
Autor:
Yuko Shirono, Vladimir Bilim, Tsutomu Anraku, Hiroo Kuroki, Akira Kazama, Masaki Murata, Kaede Hiruma, Yoshihiko Tomita
Publikováno v:
Current Oncology, Vol 30, Iss 6, Pp 5350-5365 (2023)
Advanced bladder cancer (BC) (local invasive and/or metastatic) is not curable even with cytotoxic chemotherapy, immune checkpoint inhibitors, and targeted treatment. Targeting GSK-3β is a promising novel approach in advanced BC. The induction of au
Externí odkaz:
https://doaj.org/article/928668710b4b4b77a11f83773094fb54
Autor:
Akira Kazama, Vladimir Bilim, Masayuki Tasaki, Tsutomu Anraku, Hiroo Kuroki, Yuko Shirono, Masaki Murata, Kaede Hiruma, Yoshihiko Tomita
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Immune checkpoint inhibitors (ICI) have dramatically changed the treatment of metastatic renal cell carcinoma (mRCC). Although many studies have reported biomarkers as predicting the efficacy of ICI in mRCC, they remain controversial and hav
Externí odkaz:
https://doaj.org/article/21fdee8a2293495b97344d87f8c97253
Publikováno v:
Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Key Clinical Message Undiagnosed female megalourethra can be a cause of iatrogenic bladder foreign body. Abstract Foreign bodies in the urinary bladder are relatively rare. Female megalourethra is an extremely rare congenital disorder which is usuall
Externí odkaz:
https://doaj.org/article/82fdedfafa7a405d9e1ff283f2881778
Publikováno v:
Clinical Case Reports, Vol 10, Iss 12, Pp n/a-n/a (2022)
Abstract Serum prostate‐specific antigen (PSA) levels play an important role in the screening and diagnosis of prostate cancer (PCa). The recommended PSA cut‐off in PCa screening is 4 ng/ml. We report two cases of localized PCa with low PSA level
Externí odkaz:
https://doaj.org/article/71da815e79b9456c801b1e5fbadf9fcf
Autor:
Senji Hoshi, Vladimir Bilim, Kiyotsugu Hoshi, Takuya Nakagawa, Sadanobu Sato, Rie Sakagami, Masato Konno, Takashi Kudo, Kenji Numahata, Isoji Sasagawa
Publikováno v:
Clinical Case Reports, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract Androgen deprivation therapy is a standard of care for metastatic prostate cancer. A paradoxical approach utilizing high doses of testosterone in castration‐resistant prostate cancer patients demonstrated clinical responses. Here, we repor
Externí odkaz:
https://doaj.org/article/32a1f8d1d6aa4ddcb640fec4296b9775
Autor:
Vladimir Bilim, Senji Hoshi
Publikováno v:
Clinical Case Reports, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract A 95‐year‐old man was diagnosed with left renal pelvis cancer which presented with rapid tumor growth, multiple metastases, and bilateral tender gynecomastia. Elevated serum human chorionic gonadotropin (hCG), prolactin, estradiol, and p
Externí odkaz:
https://doaj.org/article/8717a495d1b14c2fa4a1264378e9adf7
Autor:
Vladimir Bilim, Senji Hoshi
Publikováno v:
Clinical Case Reports, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract Urinary bladder cancer is frequently multifocal and has a high incidence of recurrence. Although the prostatic urethra is a frequent site of tumor relapse in patients with non‐muscle‐invasive bladder cancer treated with TURBT, such tumor
Externí odkaz:
https://doaj.org/article/67316710f1ad4188affddeba7765462a
Autor:
Hiroo Kuroki, Tsutomu Anraku, Akira Kazama, Vladimir Bilim, Masayuki Tasaki, Daniel Schmitt, Andrew P. Mazar, Francis J Giles, Andrey Ugolkov, Yoshihiko Tomita
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Glycogen synthase kinase-3 beta (GSK-3β), a serine/threonine kinase, has been identified as a potential therapeutic target in human bladder cancer. In the present study, we investigated the antitumor effect of a small molecule GSK-3β inhib
Externí odkaz:
https://doaj.org/article/1423d830529042219401ce10296db960
Autor:
Senji Hoshi, Vladimir Bilim, Kiyotsugu Hoshi, Isoji Sasagawa, Kotarou Otake, Daigo Chiba, Shinta Suenaga, Masahito Konno, Yuki Katsumata, Kento Morozumi, Jun Takemoto, Kenji Numahata, Keiichi Ito
Publikováno v:
IJU Case Reports, Vol 3, Iss 3, Pp 100-102 (2020)
Introduction Two percent of testicular germ cell tumors occur in family clusters. Here, we report metachronous testicular germ cell tumors in two brothers. Case presentation An elder brother was diagnosed at the age of 30 years old and the pathologic
Externí odkaz:
https://doaj.org/article/ee338124428c43deb9b5e2b69284873e