Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vladimír Šubr"'
Publikováno v:
Polymers, Vol 16, Iss 6, p 758 (2024)
In vitro diagnostic methods face non-specific interactions increasing their background level and influencing the efficacy and reproducibility. Currently, the most important and employed blocker of non-specific interactions is bovine serum albumin (BS
Externí odkaz:
https://doaj.org/article/e990faf3d64f4c93bf6c457b3b6f2bf4
Autor:
Klára Pospíšilová, Tomáš Knedlík, Pavel Šácha, Libor Kostka, Jiří Schimer, Jiří Brynda, Vlastimil Král, Petr Cígler, Václav Navrátil, Tomáš Etrych, Vladimír Šubr, Michael Kugler, Milan Fábry, Pavlína Řezáčová, Jan Konvalinka
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6746-6756 (2019)
Externí odkaz:
https://doaj.org/article/f19d4dce08f848dba46628cafbb8c70d
Autor:
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubr, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000529 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.3000354.].
Externí odkaz:
https://doaj.org/article/608abbed317f4c6598fe817ed9e170da
Autor:
Steffen Hackbarth, Shanghui Gao, Vladimír Šubr, Lisheng Lin, Jakob Pohl, Tomáš Etrych, Jun Fang
Recently, we reported induced anoxia as a limiting factor for photodynamic tumor therapy (PDT). This effect occurs in vivo if the amount of generated singlet oxygen that undergoes chemical reactions with cellular components exceeds the local oxygen s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45791352b97226a0aa3fbe783be5e5b
Autor:
Fang, Steffen Hackbarth, Shanghui Gao, Vladimír Šubr, Lisheng Lin, Jakob Pohl, Tomáš Etrych, Jun
Publikováno v:
Journal of Personalized Medicine; Volume 13; Issue 5; Pages: 781
Recently, we reported induced anoxia as a limiting factor for photodynamic tumor therapy (PDT). This effect occurs in vivo if the amount of generated singlet oxygen that undergoes chemical reactions with cellular components exceeds the local oxygen s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::aebf025f1156c43413b555a7b34fca66
Autor:
Rayhanul Islam, Kevin Kotalík, Vladimír Šubr, Shanghui Gao, Jian-Rong Zhou, Kazumi Yokomizo, Tomáš Etrych, Jun Fang
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 48
In this study, we developed a nanoformulation of 5-aminolevulinic acid (5-ALA) for tumor-targeted photodynamic therapy, in which 5-ALA was conjugated with a biocompatible polymer N-(2-hydroxypropyl)methacrylamide (HPMA) through the hydrazone bond, i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfaa7303ba08c9efdfa63ad335983516
https://pubmed.ncbi.nlm.nih.gov/36549553
https://pubmed.ncbi.nlm.nih.gov/36549553
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 6; Pages: 891
Hackbarth, S, Islam, R, Šubr, V, Etrych, T & Fang, J 2022, ' Singlet Oxygen In Vivo: It Is All about Intensity ', Journal of Personalized Medicine, vol. 12, no. 6, e891 . https://doi.org/10.3390/jpm12060891
Hackbarth, S, Islam, R, Šubr, V, Etrych, T & Fang, J 2022, ' Singlet Oxygen In Vivo: It Is All about Intensity ', Journal of Personalized Medicine, vol. 12, no. 6, e891 . https://doi.org/10.3390/jpm12060891
The presented work addresses the influence of illumination intensity on the amount and locations of singlet oxygen generation in tumor tissue. We used time-resolved optical detection at the typical emission wavelength around 1270 nm and at 1200 nm wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19556aa2d3944a5f0ee12d8620df116
Autor:
Libor Kostka, Ladislav Sivák, Vladimír Šubr, Jiřina Kovářová, Milada Šírová, Blanka Říhová, Radislav Sedlacek, Tomáš Etrych, Marek Kovář
Publikováno v:
Biomacromolecules. 23(6)
The derivative of protease inhibitor ritonavir (5-methyl-4-oxohexanoic acid ritonavir ester; RD) was recently recognized as a potent P-gp inhibitor and cancerostatic drug inhibiting the proteasome and STAT3 signaling. Therefore, we designed high-mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fa63dd524b409f1cd2bde2cb3226ff
https://pubmed.ncbi.nlm.nih.gov/35584053
https://pubmed.ncbi.nlm.nih.gov/35584053
Autor:
Jana Kousalová, Milada Šírová, Libor Kostka, Vladimír Šubr, Jiřina Kovářová, Kateřina Běhalová, Martin Studenovský, Marek Kovář, Tomáš Etrych
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1097da685320f0d4e0cbf8914a798666
https://pubmed.ncbi.nlm.nih.gov/35779856
https://pubmed.ncbi.nlm.nih.gov/35779856
Autor:
Vladimír Šubr, Robert Pola, Shanghui Gao, Rayhanul Islam, Takuma Hirata, Daiki Miyake, Kousuke Koshino, Jian-Rong Zhou, Kazumi Yokomizo, Jun Fang, Tomáš Etrych
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 5; Pages: 698
Biodegradable nanomedicines are widely studied as candidates for the effective treatment of various cancerous diseases. Here, we present the design, synthesis and evaluation of biodegradable polymer-based nanomedicines tailored for tumor-associated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0ab947f0bae67ebf43d18bfe0b5026
https://pubmed.ncbi.nlm.nih.gov/35629120
https://pubmed.ncbi.nlm.nih.gov/35629120