Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Vlada Melnikova"'
Autor:
Benjamin Solomon, Chris Karlovich, Ronald B. Natale, Mark G. Erlander, Mitch Raponi, Corey J. Langer, Jean-Charles Soria, Gregory A. Otterson, Heather A. Wakelee, Shirish M. Gadgeel, Mark A. Socinski, Joel W. Neal, Jason B. Litten, Lecia V. Sequist, Vassiliki A. Papadimitrakopoulou, Maurice Pérol, Sai-Hong Ignatius Ou, Vlada Melnikova, D. Ross Camidge, Stephen V. Liu, Jonathan W. Goldman, Karen L. Reckamp, Darrin Despain, Sergey Yurasov, Helena A. Yu, Aleksandra Franovic, Tarek Mekhail
Publikováno v:
JCO Precision Oncology. :1-13
Purpose Liquid biopsies represent an attractive alternative to tissue biopsies, particularly rebiopsies, in determining patient eligibility for targeted therapies. Clinical utility of urine genotyping, however, has not been explored extensively. We e
Autor:
Mitch Raponi, Ronald B. Natale, Vassiliki A. Papadimitrakopoulou, Chris Karlovich, Jonathan W. Goldman, Mark A. Socinski, Joel W. Neal, S.-H. Ou, Mark G. Erlander, Karen L. Reckamp, Gregory A. Otterson, D. Ross Camidge, Benjamin Solomon, Lecia V. Sequist, Stephen V. Liu, Sergey Yurasov, Jean-Charles Soria, Corey J. Langer, Tarek Mekhail, Darrin Despain, Heather A. Wakelee, Jason B. Litten, Shirish M. Gadgeel, Maurice Pérol, Vlada Melnikova, Helena A. Yu
Publikováno v:
Journal of Thoracic Oncology. 12:S384-S385
Autor:
Parissa Keshavarzian, Hatim Husain, Ragi Phillips, Brian Woodward, Mark G. Erlander, Vlada Melnikova, Sandeep C. Pingle
Publikováno v:
Journal of Thoracic Oncology. 12:S390
Autor:
Charles Williams, Braydon Schaible, Benjamin C. Creelan, Christine Sigua, Tawee Tanvetyanon, Jongphil Kim, Cecile Rose T. Vibat, Mark G. Erlander, Richard R. Reich, Eric B. Haura, Karen Johnson, David Gustafson, Vlada Melnikova, Sandeep C. Pingle, Jhanelle E. Gray, Scott J. Antonia
Publikováno v:
Journal of Thoracic Oncology. 12:S1200
Autor:
Eric A. Collisson, Mark G. Erlander, Inna Chen, Vlada Melnikova, Julia A. Johansen, Jennifer Geis, V.M. Raymond, Sandeep C. Pingle, Fernando F. Blanco
Publikováno v:
Cancer Research. 76:A20-A20
Introduction: An estimated 90% of pancreatic cancers harbor somatic KRAS G12/G13 mutations. The presence of circulating tumor DNA (ctDNA) KRAS mutations at diagnosis has prognostic implications, however, recent studies on small numbers of patients de
Autor:
Vivek Subbiah, Kiran Madwani, Mark G. Erlander, David S. Hong, Scott Kopetz, Sarina Anne Piha-Paul, Saege Hancock, Filip Janku, Aung Naing, Helen J. Huang, Daniel D. Karp, Rajyalakshmi Luthra, Cecile Rose T. Vibat, Apostolia Maria Tsimberidou, Bryan K. Kee, Vlada Melnikova, Debra L. Andrews, Siquing Fu, Takeo Fujii, Funda Meric-Bernstam
Publikováno v:
Cancer Research. 76:3146-3146
Introduction: Non-invasive urinary ctDNA-based liquid biopsy approach can be used to detect and track cancer driver mutations for rapid diagnosis and disease monitoring. Using highly sensitivity ctDNA mutation detection platform, we examined the dete
Autor:
Shiloh Guerrero, Mark G. Erlander, Scott M. Lippman, Brian Woodward, Cecile Rose T. Vibat, Razelle Kurzrock, Karena Kosco, Saege Hancock, Hatim Husain, Errin Samuelsz, Vlada Melnikova
Publikováno v:
Clinical Cancer Research. 22:30-30
Background: Acquisition of the EGFR T790M resistance mutation is a hallmark of disease progression in patients with metastatic EGFR mutant lung adenocarcinoma treated with first generation anti-EGFR inhibitors. Utilizing a single copy sensitivity mut
Autor:
Cecile Rose T. Vibat, Dana Agafitei, Afsaneh Barzi, Saege Hancock, Heinz-Josef Lenz, Mark G. Erlander, Vlada Melnikova, Yan Ning
Publikováno v:
Molecular Cancer Therapeutics. 14:B4-B4
Background: Radiographic imaging in patients with mCRC is the current standard of care for monitoring responses. At least 40% of patients with mCRC have tumor associated KRAS mutations, and these may be detected in tumor DNA in plasma and urine. The
Autor:
Latifa Hassaine, Timothy T. Lu, Mark G. Erlander, Benny Vittrup Jensen, Errin Samuelsz, Jason C. Poole, Cecile Rose T. Vibat, Dan Calatayud, Julia S. Johansen, Vlada Melnikova, Jane Preuss Hasselby, Saege Hancock, Inna Chen, Eric A. Collisson
Publikováno v:
Cancer Research. 75:5240-5240
Background: The median overall survival (OS) time of patients with non-resectable pancreatic cancer varies widely. Diagnostic tools are presently lacking to predict patient outcome at diagnosis. The vast majority of pancreatic tumors harbor KRAS muta
Autor:
Latifa Hassaine, Timothy T. Lu, Vlada Melnikova, Mark G. Erlander, Jason C. Poole, Karena Kosco, Saege Hancock, Cecile Rose T. Vibat, Erin Clark, Shiloh Guerrero, Errin Samuelsz
Publikováno v:
Cancer Research. 75:5238-5238
Background: Non-invasive detection and monitoring of circulating tumor DNA (ctDNA) mutations for personalized treatment of cancer patients can be realized by combining the practical advantages of urine as a ctDNA sample source with high throughput of