Fostemsavir resistance-associated polymorphisms in HIV-1 subtype C in a large cohort of treatment-naïve and treatment-experienced individuals in Botswana

Autor: Boitumelo J. L. Zuze, Botshelo T. Radibe, Wonderful T. Choga, Ontlametse T. Bareng, Natasha O. Moraka, Dorcas Maruapula, Kedumetse Seru, Patrick Mokgethi, Baitshepi Mokaleng, Nokuthula Ndlovu, Nametso Kelentse, Molly Pretorius-Holme, Roger Shapiro, Shahin Lockman, Joseph Makhema, Vlad Novitsky, Kaelo K. Seatla, Sikhulile Moyo, Simani Gaseitsiwe

Publikováno v: Microbiology Spectrum, Vol 11, Iss 6 (2023)

ABSTRACT There are limited data on the prevalence of fostemsavir (FTR) resistance-associated polymorphisms in people with HIV in Botswana. We sought to determine the prevalence of FTR resistance-associated polymorphisms in HIV-1 subtype C sequences f

Externí odkaz: https://doaj.org/article/8a3484c8f0984aef98f28951e867c1e8

Global associations of key populations with HIV-1 recombinants: a systematic review, global survey, and individual participant data meta-analysis

Autor: Nkazi Nchinda, Ramyiadarsini Elangovan, Jason Yun, Leslie Dickson-Tetteh, Shona Kirtley, Joris Hemelaar, WHO-UNAIDS Network for HIV Isolation and Characterisation, Alash'le G. Abimiku, Simon Agwale, Chris Archibald, Boaz Avidor, Barbás María Gabriela, Francoise Barre-Sinoussi, Banson Barugahare, El Hadj Belabbes, Silvia Bertagnolio, Deborah Birx, Aleksei F. Bobkov, James Brandful, Helba Bredell, Catherine A. Brennan, James Brooks, Marie Bruckova, Luigi Buonaguro, Franco Buonaguro, Stefano Buttò, Anne Buve, Mary Campbell, Jean Carr, Alex Carrera, Manuel Gómez Carrillo, Connie Celum, Beth Chaplin, Macarthur Charles, Dimitrios Chatzidimitriou, Zhiwei Chen, Katsumi Chijiwa, David Cooper, Philip Cunningham, Anoumou Dagnra, Cillian F. de Gascun, Julia Del Amo, Elena Delgado, Ursula Dietrich, Dominic Dwyer, Dennis Ellenberger, Barbara Ensoli, Max Essex, Herve Fleury, Peter N. Fonjungo, Vincent Foulongne, Deepak A. Gadkari, Feng Gao, Federico García, Roger Garsia, Guy Michel Gershy-Damet, Judith R. Glynn, Ruth Goodall, Zehava Grossman, Monick Lindenmeyer Guimarães, Beatrice Hahn, Raph L. Hamers, Osamah Hamouda, Ray Handema, Xiang He, Joshua Herbeck, David D. Ho, Africa Holguin, Mina Hosseinipour, Gillian Hunt, Masahiko Ito, Mohamed Ali Bel Hadj Kacem, Erin Kahle, Pontiano Kaleebu, Marcia Kalish, Adeeba Kamarulzaman, Chun Kang, Phyllis Kanki, Edward Karamov, Jean-Claude Karasi, Kayitesi Kayitenkore, Tony Kelleher, Dwip Kitayaporn, Leondios G. Kostrikis, Claudia Kucherer, Claudia Lara, Thomas Leitner, Kirsi Liitsola, Jai Lingappa, Marek Linka, Ivette Lorenzana de Rivera, Vladimir Lukashov, Shlomo Maayan, Luzia Mayr, Francine McCutchan, Nicolas Meda, Elisabeth Menu, Fred Mhalu, Doreen Mloka, John L. Mokili, Brigitte Montes, Orna Mor, Mariza Morgado, Fausta Mosha, Awatef Moussi, James Mullins, Rafael Najera, Mejda Nasr, Nicaise Ndembi, Joel R. Neilson, Vivek R. Nerurkar, Florian Neuhann, Claudine Nolte, Vlad Novitsky, Philippe Nyambi, Marianna Ofner, Fem J. Paladin, Anna Papa, Jean Pape, Neil Parkin, Chris Parry, Martine Peeters, Alexandra Pelletier, Lucía Pérez-Álvarez, Deenan Pillay, Angie Pinto, Trinh Duy Quang, Cecilia Rademeyer, Filimone Raikanikoda, Mark A. Rayfield, Jean-Marc Reynes, Tobias Rinke de Wit, Kenneth E. Robbins, Morgane Rolland, Christine Rousseau, Jesus Salazar-Gonzales, Hanan Salem, Mika Salminen, Horacio Salomon, Paul Sandstrom, Mario L. Santiago, Abdoulaye D. Sarr, Bryan Schroeder, Michel Segondy, Philippe Selhorst, Sylvester Sempala, Jean Servais, Ansari Shaik, Yiming Shao, Amine Slim, Marcelo A. Soares, Elijah Songok, Debbie Stewart, Julie Stokes, Shambavi Subbarao, Ruengpung Sutthent, Jun Takehisa, Amilcar Tanuri, Kok Keng Tee, Kiran Thapa, Michael Thomson, Tyna Tran, Willy Urassa, Hiroshi Ushijima, Philippe van de Perre, Guido van der Groen, Kristel van Laethem, Joep van Oosterhout, Ard van Sighem, Eric van Wijngaerden, Anne-Mieke Vandamme, Jurgen Vercauteren, Nicole Vidal, Lesley Wallace, Carolyn Williamson, Dawit Wolday, Jianqing Xu, Chunfu Yang, Linqi Zhang, Rong Zhang

Publikováno v: Frontiers in Public Health, Vol 11 (2023)

IntroductionGlobal HIV infections due to HIV-1 recombinants are increasing and impede prevention and treatment efforts. Key populations suffer most new HIV infections, but their role in the spread of HIV-1 recombinants is unknown. We conducted a glob

Externí odkaz: https://doaj.org/article/c1dc28e1047a4d5f998d0e6d54278633

DirectDetect SARS-CoV‑2 Direct Real-Time RT-PCR Study Using Patient Samples

Autor: Dulguunnaran Naranbat, Lindsay Schneider, Rami Kantor, Curt G. Beckwith, Lauri Bazerman, Fizza Gillani, Sujata Sahu, Kim Rapoza, Soya Sam, Vlad Novitsky, Jimin Shin, Evelyn Hipolito, Isabella Diaz, Daniella Carnevale, Anubhav Tripathi

Publikováno v: ACS Omega, Vol 7, Iss 6, Pp 4945-4955 (2022)

Externí odkaz: https://doaj.org/article/fc1c0d279eef43b4987fd7bef10e058a

An Automated Bioinformatics Pipeline Informing Near-Real-Time Public Health Responses to New HIV Diagnoses in a Statewide HIV Epidemic

Autor: Mark Howison, Fizza S. Gillani, Vlad Novitsky, Jon A. Steingrimsson, John Fulton, Thomas Bertrand, Katharine Howe, Anna Civitarese, Lila Bhattarai, Meghan MacAskill, Guillermo Ronquillo, Joel Hague, Casey W. Dunn, Utpala Bandy, Joseph W. Hogan, Rami Kantor

Publikováno v: Viruses, Vol 15, Iss 3, p 737 (2023)

Molecular HIV cluster data can guide public health responses towards ending the HIV epidemic. Currently, real-time data integration, analysis, and interpretation are challenging, leading to a delayed public health response. We present a comprehensive

Externí odkaz: https://doaj.org/article/a74cd0322ca94271af5ec0666b8eff41

Beyond HIV outbreaks: protocol, rationale and implementation of a prospective study quantifying the benefit of incorporating viral sequence clustering analysis into routine public health interventions

Autor: Philip A Chan, Joseph W Hogan, John Fulton, Jon A Steingrimsson, Mark Howison, Vlad Novitsky, Fizza S Gillani, Thomas Bertrand, Anna Civitarese, Katharine Howe, Guillermo Ronquillo, Benjamin Lafazia, Zoanne Parillo, Theodore Marak, Lila Bhattarai, Casey Dunn, Utpala Bandy, Nicole Alexander Scott, Rami Kantor

Publikováno v: BMJ Open, Vol 12, Iss 4 (2022)

Introduction HIV continues to have great impact on millions of lives. Novel methods are needed to disrupt HIV transmission networks. In the USA, public health departments routinely conduct contact tracing and partner services and interview newly HIV-

Externí odkaz: https://doaj.org/article/d9ef03466b1541a686f75b356c0f2684