Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vjacheslav V. Severov"'
Autor:
Maria A. Lagarkova, Vjacheslav V. Severov, Galina E. Pozmogova, Timofei S. Zatsepin, Anton V. Turaev, Andrey V. Aralov, Ekaterina Isaakova, M. V. Sardushkin, Anna M. Varizhuk, A. N. Bogomazova
Publikováno v:
Biosensorsbioelectronics. 175
We report the design of robust sensors for measuring intracellular pH, based on the native DNA i-motifs (iMs) found in neurodegeneration- or carcinogenesis-related genes. Those iMs appear to be genomic regulatory elements and might modulate transcrip
Autor:
Andrey V. Aralov, Tatiana A Nikolenko, Egor Shitikov, Vjacheslav V. Severov, Sofia A Lizunova, Vladimir B. Tsvetkov, Anna M. Varizhuk, Galina E. Pozmogova, Evgeny S. Belyaev, Igor Ivanov
Publikováno v:
Organicbiomolecular chemistry. 18(31)
G-quadruplexes (G4) represent one class of non-canonical secondary nucleic acid structures that are currently regarded as promising and attractive targets for anti-cancer, anti-viral and antibacterial therapy. Herein, we probe a new i-clamp-inspired
Autor:
A.N. Bogomazova, Artem V. Luzhin, Galina E. Pozmogova, Maria A. Lagarkova, Omar L. Kantidze, Vjacheslav V. Severov, Anna Varizhuk, Tatjana Vedekhina, Polina Tikhonova, Ekaterina Isaakova, R. Sultanov, Ksenia Klimina, Vladimir B. Tsvetkov, Iulia I. Pavlova
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7090, p 7090 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7090, p 7090 (2021)
G-quadruplex (G4) sites in the human genome frequently colocalize with CCCTC-binding factor (CTCF)-bound sites in CpG islands (CGIs). We aimed to clarify the role of G4s in CTCF positioning. Molecular modeling data suggested direct interactions, so w
Autor:
Knizhnik E; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Chumakov S; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Svetlova J; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Pavlova I; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Khodarovich Y; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Research and Educational Resource Center for Cellular Technologies of The Peoples' Friendship University of Russia, 117198 Moscow, Russia., Brylev V; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Severov V; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Alieva R; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Raman Spectroscopy Laboratory, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Kozlovskaya L; Chumakov Scientific Center for Research and Development of Immune-and-Biological Products, Russian Academy of Sciences (Institute of Poliomyelitis), 108819 Moscow, Russia., Andreev D; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia., Aralov A; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Varizhuk A; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Publikováno v:
Biomolecules [Biomolecules] 2023 Nov 17; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 17.
Autor:
Pavlova I; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine, 119435 Moscow, Russia.; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Iudin M; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine, 119435 Moscow, Russia.; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Surdina A; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine, 119435 Moscow, Russia., Severov V; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine, 119435 Moscow, Russia., Varizhuk A; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine, 119435 Moscow, Russia.; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Publikováno v:
Genes [Genes (Basel)] 2023 May 13; Vol. 14 (5). Date of Electronic Publication: 2023 May 13.
Autor:
Pavlova I; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Moscow Institute of Physics and Technology, Dolgoprudny, 141701, Russia., Barinov N; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia., Novikov R; Engenlhardt Institute of Molecular Biology, Moscow, 119991, Russia; N.D. Zelinsky Institute of Organic Chemistry, Moscow, 19991, Russia., Severov V; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia., Iudin M; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Moscow Institute of Physics and Technology, Dolgoprudny, 141701, Russia., Vedekhina T; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia., Larin A; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, 119435, Russia., Babenko V; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, 119435, Russia., Aralov A; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, 117997, Russia., Gnuchikh E; National Research Center Kurchatov Institute, Kurchatov Genomic Center, Moscow, 123182, Russia., Sardushkin M; Mendeleev University of Chemical Technology of Russia, 125047, Moscow, Russia., Klinov D; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Peoples' Friendship University of Russia (RUDN University), 117198, Moscow, Russia., Tsvetkov V; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Institute of Biodesign and Complex System Modeling, I.M. Sechenov First Moscow State Medical University, Moscow, 119991, Russia; A.V. Topchiev Institute of Petrochemical Synthesis, Leninsky Prospect Str. 29, Moscow, 119991, Russia. Electronic address: v.b.tsvetkov@gmail.com., Varizhuk A; Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, 119435, Russia; Moscow Institute of Physics and Technology, Dolgoprudny, 141701, Russia; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, 119435, Russia. Electronic address: annavarizhuk@gmail.com.
Publikováno v:
Biochimie [Biochimie] 2023 Jan; Vol. 204, pp. 8-21. Date of Electronic Publication: 2022 Sep 03.
Autor:
Tikhonova P; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Pavlova I; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Isaakova E; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Tsvetkov V; A.V. Topchiev Institute of Petrochemical Synthesis RAS, 119071 Moscow, Russia.; WCRC Russia 'Digital Biodesign and Personalized Healthcare', Sechenov First Moscow State Medical University, 119146 Moscow, Russia., Bogomazova A; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Vedekhina T; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Luzhin AV; Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Sultanov R; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Severov V; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Klimina K; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Kantidze OL; Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Pozmogova G; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Lagarkova M; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Varizhuk A; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Publikováno v:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 30; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 30.