Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vivienne S Lee"'
Autor:
Newsha Raoufi-Rad, Lucinda S McRobb, Vivienne S Lee, David Bervini, Michael Grace, Jaysree Ukath, Joshua Mchattan, Varun K A Sreenivasan, T T Hong Duong, Zhenjun Zhao, Marcus A Stoodley
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185393 (2017)
Focussed radiosurgery may provide a means of inducing molecular changes on the luminal surface of diseased endothelium to allow targeted delivery of novel therapeutic compounds. We investigated the potential of ionizing radiation to induce surface ex
Externí odkaz:
https://doaj.org/article/c391d45beed64d04ac15d8978e2536c0
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 10, p 305 (2024)
Aims: The goal of this study was to establish a simple model of 3D endothelial spheroids with mosaic gene expression using adeno-associated virus (AAV) transduction, with a future aim being to study the activity of post-zygotic mutations common to va
Externí odkaz:
https://doaj.org/article/dabc1b26d8ad4059a6155bd806e16eeb
Autor:
Zhenjun Zhao, Lucinda S. McRobb, Valery Combes, Vivienne S. Lee, Andrew J. Gauden, S.O. Ugoya, Georges E. Grau, David W. Inglis, Marcus A. Stoodley, Vaughan Moutrie, E.D. Santos, Sinduja Subramanian
Publikováno v:
Thrombosis Research. 167:104-112
© 2018 Elsevier Ltd Background: Our goal is to develop a vascular targeting treatment for brain arteriovenous malformations (AVMs). Externalized phosphatidylserine has been established as a potential biomarker on the endothelium of irradiated AVM bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7716508fab41102aad7334b8e5efd29
https://doi.org/10.1016/j.thromres.2018.05.016
https://doi.org/10.1016/j.thromres.2018.05.016
Autor:
Vivienne S. Lee, Vaughan Moutrie, Marcus A. Stoodley, Lucinda S. McRobb, Andrew J. Gauden, Sinduja Subramanian, Zhenjun Zhao
Publikováno v:
Translational stroke research. 11(4)
Brain arteriovenous malformations (AVMs) are a significant cause of intracerebral hemorrhage in children and young adults. Currently, one third of patients have no viable treatment options. Vascular targeting agents (VTAs) are being designed to deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48eb27d4acf16860130be540855e9877
https://pubmed.ncbi.nlm.nih.gov/31802427
https://pubmed.ncbi.nlm.nih.gov/31802427
Autor:
Jaysree Ukath, Zhenjun Zhao, Michael Grace, Michael Johnson, Lisa M. Sedger, Lucinda S. McRobb, Marcus A. Stoodley, Vivienne S. Lee, Biyi Chen
Publikováno v:
Journal of Neurosurgery. 124:1780-1787
OBJECT Stereotactic radiosurgery (SRS) is an established intervention for brain arteriovenous malformations (AVMs). The processes of AVM vessel occlusion after SRS are poorly understood. To improve SRS efficacy, it is important to understand the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fb749e6a2adcb87c029b1c1e366f28
https://doi.org/10.3171/2015.4.jns142129
https://doi.org/10.3171/2015.4.jns142129
Metastatic melanoma can be highly refractory to conventional radiotherapy and chemotherapy but combinatorial-targeted therapeutics are showing greater promise on improving treatment efficacy. Previous studies have shown that knockdown of Forkhead box
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb70ad9c87aec46d87555fb235d1bbf
https://europepmc.org/articles/PMC6202528/
https://europepmc.org/articles/PMC6202528/
Autor:
Rachel R. Ogorzalek Loo, David Bervini, Michael Grace, Joseph A. Loo, Mark P. Molloy, Dyna I. Shirasaki, Margaret Simonian, Marcus A. Stoodley, Vivienne S. Lee
Publikováno v:
Simonian, Margaret; Shirasaki, Dyna; Lee, Vivienne S.; Bervini, David; Grace, Michael; Ogorzalek Loo, Rachel R.; Loo, Joseph A.; Molloy, Mark P.; Stoodley, Marcus A. (2018). Proteomics identification of radiation-induced changes of membrane proteins in the rat model of arteriovenous malformation in pursuit of targets for brain AVM molecular therapy. Clinical proteomics, 15(43), p. 43. BioMed Central 10.1186/s12014-018-9217-x
Clinical Proteomics
Clinical Proteomics, Vol 15, Iss 1, Pp 1-8 (2018)
Clinical Proteomics
Clinical Proteomics, Vol 15, Iss 1, Pp 1-8 (2018)
Background Rapid identification of novel targets and advancement of a vascular targeting strategy requires a comprehensive assessment of AVM endothelial membrane protein changes in response to irradiation. The aim of this study is to provide addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a4d9f553fc33f6293bb9c1af6d83b2
Autor:
Lucinda S. McRobb, Michael Grace, Newsha Raoufi-Rad, Zhenjun Zhao, Marcus A. Stoodley, David Bervini, Vivienne S. Lee, Varun K. A. Sreenivasan, Joshua J. McHattan, T. T. Hong Duong, Jaysree Ukath
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0185393 (2017)
Raoufi-Rad, Newsha; McRobb, Lucinda S; Lee, Vivienne S; Bervini, David; Grace, Michael; Ukath, Jaysree; Mchattan, Joshua; Sreenivasan, Varun K A; Duong, T T Hong; Zhao, Zhenjun; Stoodley, Marcus A (2017). In vivo imaging of endothelial cell adhesion molecule expression after radiosurgery in an animal model of arteriovenous malformation. PLoS ONE, 12(9), e0185393. Public Library of Science 10.1371/journal.pone.0185393
PLoS ONE, Vol 12, Iss 9, p e0185393 (2017)
Raoufi-Rad, Newsha; McRobb, Lucinda S; Lee, Vivienne S; Bervini, David; Grace, Michael; Ukath, Jaysree; Mchattan, Joshua; Sreenivasan, Varun K A; Duong, T T Hong; Zhao, Zhenjun; Stoodley, Marcus A (2017). In vivo imaging of endothelial cell adhesion molecule expression after radiosurgery in an animal model of arteriovenous malformation. PLoS ONE, 12(9), e0185393. Public Library of Science 10.1371/journal.pone.0185393
Focussed radiosurgery may provide a means of inducing molecular changes on the luminal surface of diseased endothelium to allow targeted delivery of novel therapeutic compounds. We investigated the potential of ionizing radiation to induce surface ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e866279a82ddb63f8525625ef8417b
https://pubmed.ncbi.nlm.nih.gov/28949989
https://pubmed.ncbi.nlm.nih.gov/28949989
Phosphatidylserine Translocation after Radiosurgery in an Animal Model of Arteriovenous Malformation
Autor:
Nirav J. Patel, Lucinda S. McRobb, Jude V. Amal Raj, Saleh R. Kashba, Anas Sarwar Qureshi, Joshua J. McHattan, Michael Grace, Newsha Raoufi Rad, Vivienne S. Lee, Zhenjun Zhao, Marcus A. Stoodley, Hong Duong
Publikováno v:
Radiation research. 187(6)
Phosphatidylserine (PS) is asymmetrically distributed across the plasma membrane, located predominantly on the inner leaflet in healthy cells. Translocation of PS to the outer leaflet makes it available as a target for biological therapies. We examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d94ffba440c59465864d0d5965cde05
https://pubmed.ncbi.nlm.nih.gov/28414573
https://pubmed.ncbi.nlm.nih.gov/28414573
Autor:
Lucinda S McRobb, Vivienne S Lee, Santosh G Thomas, Markus Wiedmann, Jude V Amal Raj, Zhenjun Zhao, Michael Grace, Vaughan Moutrie, Matthew McKay, Mark Molloy, Marcus A Stoodley
Publikováno v:
Stroke. 47
Introduction: Brain arteriovenous malformations (AVMs) are a significant cause of hemorrhagic stroke. Almost one third are untreatable using current methods. We aim to use stereotactic radiosurgery as a priming tool to elicit novel protein expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9385a502d9f2691bb1b70939fd9be81c
https://doi.org/10.1161/str.47.suppl_1.wmp120
https://doi.org/10.1161/str.47.suppl_1.wmp120