Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vivienne Lea"'
Autor:
Vincent Ho, Liping Chung, Stephanie H. Lim, Yafeng Ma, Bin Wang, Vivienne Lea, Askar Abubakar, Weng Ng, Mark Lee, Tara L. Roberts, Wei Chua, C. Soon Lee
Publikováno v:
Gastrointestinal Disorders, Vol 4, Iss 3, Pp 165-179 (2022)
The DNA damage response (DDR) is critical for maintaining genome stability, and abnormal DDR—resulting from mutations in DNA damage-sensing and repair proteins—is a hallmark of cancer. Here, we aimed to investigate the predictive power of DDR gen
Externí odkaz:
https://doaj.org/article/3fee0a04d5f94af0a056945950b6eae8
Autor:
Paul Habashy, Vivienne Lea, Kate Wilkinson, Bin Wang, Xiao-Juan Wu, Tara Laurine Roberts, Weng Ng, Tristan Rutland, Joseph William Po, Therese Becker, Joseph Descallar, Mark Lee, Scott Mackenzie, Ruta Gupta, Wendy Cooper, Stephanie Lim, Wei Chua, Cheok Soon Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17509 (2023)
KRAS and BRAF mutation rates in colorectal cancer (CRC) reported from various mono-ethnic studies vary amongst different ethnic groups. However, these differences in mutation rates may not be statistically significant or may be due to differences in
Externí odkaz:
https://doaj.org/article/87a722c53d4a4b7ba9f23c54838dfb71
Autor:
Udit Nindra, Abhijit Pal, Vivienne Lea, Stephanie Hui-Su Lim, Kate Wilkinson, Ray Asghari, Tara L Roberts, Therese M Becker, Mahtab Farzin, Tristan Rutland, Mark Lee, Scott MacKenzie, Weng Ng, Bin Wang, C Soon Lee, Wei Chua
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292087 (2023)
BackgroundNext generation sequencing (NGS) is increasingly used in standard clinical practice to identify patients with potentially actionable mutations. Stratification of NGS mutation tiers is currently based on the European Society of Medical Oncol
Externí odkaz:
https://doaj.org/article/96a4f02f3945468bab367622f96e9e7b
Autor:
Vincent Ho, Liping Chung, Amandeep Singh, Vivienne Lea, Askar Abubakar, Stephanie H. Lim, Weng Ng, Mark Lee, Paul de Souza, Joo-Shik Shin, Cheok Soon Lee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The MRE11/RAD50/NBS1 (MRN) complex plays an essential role in detecting and repairing double-stranded breaks, and thus the potential roles of MRE11, RAD50 and NBS1 proteins in the pathogenesis of various cancers is the subject of
Externí odkaz:
https://doaj.org/article/5e214742cec648bfa017871cf3777701
Publikováno v:
Brain Sciences, Vol 11, Iss 9, p 1238 (2021)
Introduction: This paper describes a case of bi-frontal vasogenic oedema associated with bilateral frontal lobe and left parietal lobe white matter lesions where extensive investigations, including brain biopsy, failed to establish a diagnosis. Case
Externí odkaz:
https://doaj.org/article/d6f4e8398f8d46a489bb9ee2d7f65190
Autor:
Vincent Ho, Liping Chung, Amandeep Singh, Vivienne Lea, Askar Abubakar, Stephanie H. Lim, Wei Chua, Weng Ng, Mark Lee, Tara L. Roberts, Paul de Souza, Cheok Soon Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1768 (2020)
The DNA damage response enables cells to survive and maintain genome integrity. RAD52 is a DNA-binding protein involved in the homologous recombination in DNA repair, and is important for the maintenance of tumour genome integrity. We investigated po
Externí odkaz:
https://doaj.org/article/7bf69d1c53ce409cb010a9c89167cc04
Autor:
Liping Chung, Amandeep Singh, Wei Chua, Vincent T. Ho, Cheok Soon Lee, Askar Abubakar, Tara L. Roberts, Stephanie H Lim, Paul de Souza, Vivienne Lea, Mark T Lee, Weng Ng
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1768 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 5
International Journal of Molecular Sciences
Volume 21
Issue 5
The DNA damage response enables cells to survive and maintain genome integrity. RAD52 is a DNA-binding protein involved in the homologous recombination in DNA repair, and is important for the maintenance of tumour genome integrity. We investigated po
Autor:
Vivienne Lea, Ray Asghari, Weng Ng, L. Kim, X.J. Wu, Cheok Soon Lee, Wei Chua, P. Habashy, Kate Wilkinson, B. Wang, Tara L. Roberts, Stephanie H Lim
Publikováno v:
Pathology. 53:S59
Autor:
Andrew J. A. Holland, Deepak Burad, Marie Therese Manipadam, Vivienne Lea, Pratibha Nanjundaiah, Theresa Ly, Susan Jehangir, Elanthenral Sigamani
Publikováno v:
Pediatric bloodcancer. 66(4)
BACKGROUND Criteria for the pathological classification of adult adrenocortical tumours (ACTs) have been found to overestimate the malignant potential of childhood ACTs. We sought to evaluate the accuracy and utility of criteria developed for paediat
Publikováno v:
BMJ Case Reports
We report the case of a 24-year-old man who presented with a 5-week history of painful right inguinal lymphadenopathy, weight loss and non-ulcerative foreskin mass. The patient’s symptoms progressed despite initial antibiotic therapy. The foreskin