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Abstract 136: Understanding Multi-allelic Heterozygous Variant Contributions to Dilated Cardiomyopathy

Autor: Cassandra Happe, Dekker Deacon, Rossin Erbe, Kevin Tenerelli, Vivien Tran, Eric Alder, Neil Chi, Adam Engler

Publikováno v: Circulation Research. 121

Dilated cardiomyopathy (DCM) is a multivariate disease with poorly understood mechanisms, but recently 30+ different mutations have been suggested to contribute to disease pathology. We have identified the first incidence where a family with high DCM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71dfc94577ace00ee854a2124cd6648d
https://doi.org/10.1161/res.121.suppl_1.136

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Acute Myeloid Leukemia Expands Osteoprogenitor Rich Niche in the Bone Marrow but Resorbs Mature Bone Causing Osteopenia/Osteoporosis in Animal Models

Autor: Bin Yuan, Stanley Ly, Venkata Lokesh Battula, Vivien Tran, Khoa Nguyen, Michael Andreeff, Jared K. Burks, Benoit deCrombrugghe, Kiersten L. Maldonado, Xin Zhou, Charles Kinglsey

Publikováno v: Blood. 132:86-86

Acute myeloid leukemia (AML) is one of the most aggressive hematological malignancy that originates in the bone marrow (BM). Despite advances in the molecular characterization of AML, factors regulating its progression are still not known. Among seve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf3fa1ff8cc8037ee7f2c0ecc9b535ac
https://doi.org/10.1182/blood-2018-99-117258

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