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Publikováno v:
Section on Hospital Medicine Program.
In 2013, the American Academy of Pediatrics’ position statement, “Guiding Principles for Pediatric Hospital Medicine (PHM) Programs,” emphasized the importance of professional development for each PHM physician. However, little is published abo
Autor:
Jing Zhang, Dennis J. Selkoe, Michael S. Wolfe, Wenjuan Ye, Han-Xun Wei, Dai Lu, Yongli Gu, Pamela Osenkowski, Corinne E. Augelli-Szafran, Vivien Sun
Publikováno v:
Bioorg Med Chem Lett
One therapeutic approach for Alzheimer's disease is to inhibit the cleavage of the amyloid precursor protein (APP) by γ-secretase. At the beginning of a series of studies from our laboratories, a series of novel γ-amino alcohols (1) were found to p