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pro vyhledávání: '"Vivien Lacone"'
Autor:
Virginie Blot, Julie Hunault, Jacques Le Pendu, Didier Dubreuil, Anne-Laure Turcot-Dubois, Laurent Micouin, Marc Bonneville, Vivien Lacone, Thomas Lecourt, Séverine Marionneau, Jézabelle Rocher, Muriel Pipelier, Monique Clément, J.Y. Douillard
Publikováno v:
Journal of Medicinal Chemistry. 52:4960-4963
4-Deoxy-alpha-GalCer analogues are considered weaker agonists than KRN7000 for the stimulation of human iNKT cells, but this remains strongly debated. In this work, we described a strategy toward 4-deoxy-alpha-GalCers with, as a key step, a metathesi