Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Vivien Kirk"'
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 2, p e1005275 (2017)
Saliva is an essential part of activities such as speaking, masticating and swallowing. Enzymes in salivary fluid protect teeth and gums from infectious diseases, and also initiate the digestion process. Intracellular calcium (Ca2+) plays a critical
Externí odkaz:
https://doaj.org/article/2a032bc58cbc441fbd130420785f054e
Publikováno v:
SIAM Journal on Applied Dynamical Systems. 21:982-1029
Phenomena in chemistry, biology and neuroscience are often modelled using ordinary differential equations (ODEs) in which the right-hand-side is comprised of terms which correspond to individual 'processes' or 'fluxes'. Frequently, these ODEs are cha
Publikováno v:
Bulletin of Mathematical Biology. 81:1394-1426
We have constructed a spatiotemporal model of $$\hbox {Ca}^{2+}$$ dynamics in parotid acinar cells, based on new data about the distribution of inositol trisphophate receptors (IPR). The model is solved numerically on a mesh reconstructed from images
Autor:
James Sneyd, Paula J. Bartlett, Juliana C. Corrêa-Velloso, Andrew P. Thomas, Vivien Kirk, Ielyaas Cloete
Publikováno v:
Journal of theoretical biology. 518
Calcium (Ca2+) oscillations in hepatocytes have a wide dynamic range. In particular, recent experimental evidence shows that agonist stimulation of the P2Y family of receptors leads to qualitatively diverse Ca2+ oscillations. We present a new model o
Publikováno v:
Journal of theoretical biology. 503
Calcium (Ca
Publikováno v:
The European Physical Journal Special Topics. 227:603-614
Multi-spike bursting of the membrane potential is understood to be a key mechanism for cell signalling in neurons. During the active phase of a burst, the voltage potential across the cell membrane exhibits a series of spikes. This is followed by a s
Publikováno v:
SIAM Journal on Applied Dynamical Systems. 17:350-379
The behavior of systems with fast and slow time scales is organized by families of locally invariant slow manifolds. Recently, numerical methods have been developed for the approximation of attract...
Publikováno v:
The European Physical Journal Special Topics. 225:2601-2612
Many models of neuronal activity exhibit complex oscillations in response to an input from other neurons in a network or to an input from a stimulus. We consider the effect of a single short stimulus on a simple model designed to mimic some features
Publikováno v:
Journal of Theoretical Biology. 503:110390
Calcium (Ca2+) oscillations in hepatocytes control many critical cellular functions, including glucose metabolism and bile secretion. The mechanisms underlying repetitive Ca2+ oscillations and how these mechanisms regulate these oscillations is not f
Publikováno v:
Bull Math Biol
We have constructed a spatiotemporal model of [Formula: see text] dynamics in parotid acinar cells, based on new data about the distribution of inositol trisphophate receptors (IPR). The model is solved numerically on a mesh reconstructed from images