Zobrazeno 1 - 10
of 954
pro vyhledávání: '"Vivien J"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Various techniques using fluorescent reporter probes have been developed, such as GFP transgenic mouse lines that are used to detect spatial–temporal expression levels of genes. Although GFP expression is largely considered non-toxic, rece
Externí odkaz:
https://doaj.org/article/a2dab7df0da4440b8c710ea357988976
Autor:
Scott M. Reid, Alexander M. P. Byrne, Fabian Z. X. Lean, Craig S. Ross, Andrei Pascu, Richard Hepple, Maria Dominguez, Susanne Frost, Vivien J. Coward, Alejandro Núñez, Joe James, Levon Stephan, James N. Aegerter, Ian H. Brown, Ashley C. Banyard
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
A free-range organic broiler (Gallus gallus domesticus) premises in Staffordshire was infected by high pathogenicity avian influenza virus (HPAIV) H5N8 during the 2020–2021 epizootic in the United Kingdom (UK). Following initial confirmation of the
Externí odkaz:
https://doaj.org/article/ed07503636a441759808d719e86dde74
Autor:
Alexander Fröhlich, Abigail L. Pfaff, Ben Middlehurst, Lauren S. Hughes, Vivien J. Bubb, John P. Quinn, Sulev Koks
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract SINE-VNTR-Alu (SVA) retrotransposons are transposable elements which represent a source of genetic variation. We previously demonstrated that the presence/absence of a human-specific SVA, termed SVA_67, correlated with the progression of Par
Externí odkaz:
https://doaj.org/article/d2f476689c424207a54da2ebbb79a360
Autor:
Ashley Hall, Ben Middlehurst, Max A. M. Cadogan, Xylena Reed, Kimberley J. Billingsley, Vivien J. Bubb, John P. Quinn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract SINE-VNTR-Alu (SVA) retrotransposons represent mobile regulatory elements that have the potential to influence the surrounding genome when they insert into a locus. Evolutionarily recent mobilisation has resulted in loci in the human genome
Externí odkaz:
https://doaj.org/article/df9519328cc6452badeef6cde5500070
Autor:
Winston W. Y. Kao, Jianhua Zhang, Jhuwala Venkatakrishnan, Shao-Hsuan Chang, Yong Yuan, Osamu Yamanaka, Ying Xia, Tarsis F. Gesteira, Sudhir Verma, Vivien J. Coulson-Thomas, Chia-Yang Liu
Publikováno v:
Cells, Vol 13, Iss 19, p 1599 (2024)
The synthetic peptide of lumican C-terminal 13 amino acids with the cysteine replaced by an alanine, hereafter referred to as lumikine (LumC13C-A: YEALRVANEVTLN), binds to TGFβ type I receptor/activin-like kinase5 (TBR1/ALK5) in the activated TGFβ
Externí odkaz:
https://doaj.org/article/edf81ec16f7c43ccb0e1b8e2f51c11a5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Long interspersed nuclear element-1 (LINE-1/L1) retrotransposons make up 17% of the human genome. They represent one class of transposable elements with the capacity to both mobilize autonomously and in trans via the mobilization of other el
Externí odkaz:
https://doaj.org/article/0d59d7baa0db4388a6876ea34293d174
Publikováno v:
Cells, Vol 13, Iss 13, p 1105 (2024)
The cornea is continuously exposed to injuries, ranging from minor scratches to deep traumas. An effective healing mechanism is crucial for the cornea to restore its structure and function following major and minor insults. Transforming Growth Factor
Externí odkaz:
https://doaj.org/article/6d685a1590a34b4e8324862e30ae37b6
Publikováno v:
Cells, Vol 13, Iss 9, p 748 (2024)
Stem cells (SCs) undergo asymmetric division, producing transit-amplifying cells (TACs) with increased proliferative potential that move into tissues and ultimately differentiate into a specialized cell type. Thus, TACs represent an intermediary stat
Externí odkaz:
https://doaj.org/article/f7105714124446d9a1aaec4953df2883
Autor:
Alexander Fröhlich, Lauren S. Hughes, Ben Middlehurst, Abigail L. Pfaff, Vivien J. Bubb, Sulev Koks, John P. Quinn
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundSINE-VNTR-Alu (SVA) retrotransposons are hominid-specific elements which have been shown to play important roles in processes such as chromatin structure remodelling and regulation of gene expression demonstrating that these repetitive elem
Externí odkaz:
https://doaj.org/article/38c1abd247cb4339b4a62507e653761a
Autor:
Lauren S. Hughes, Alexander Fröhlich, Abigail L. Pfaff, Vivien J. Bubb, John P. Quinn, Sulev Kõks
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 358 (2024)
Transposable elements (TEs) are repetitive elements which make up around 45% of the human genome. A class of TEs, known as SINE-VNTR-Alu (SVA), demonstrate the capacity to mobilise throughout the genome, resulting in SVA polymorphisms for their prese
Externí odkaz:
https://doaj.org/article/af72b72ad85e498e883cdb4b796d626d