Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Vivianne I. Otto"'
1
The manifold roles of sialic acid for the biological functions of endothelial glycoproteins
Autor: Vivianne I. Otto, Marco D'Addio, Jasmin Frey
Publikováno v: Glycobiology
Vascular endothelia are covered with a dense glycocalix that is heavily sialylated. Sialylation of vascular glycoconjugates is involved in the regulation of cell–cell interactions, be it among endothelial cells at cell junctions or between endothel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba5fbd3d410270e88f9c5856e7bd37a
http://europepmc.org/articles/PMC7372927
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2
Sialoglycans on lymphatic endothelial cells augment interactions with Siglec‐1 (CD169) of lymph node macrophages
Autor: Vivianne I. Otto, Michael Detmar, Carlotta Tacconi, Catharina D. Commerford, Jasmin Frey, Richard D. Cummings, Cornelia Halin, Marco D'Addio
Publikováno v: The FASEB Journal, 35 (11)
Cellular interactions between endothelial cells and macrophages regulate macrophage localization and phenotype, but the mechanisms underlying these interactions are poorly understood. Here we explored the role of sialoglycans on lymphatic endothelial
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990c5edca16e5cee6a8e8d04e606c34c
https://doi.org/10.1096/fj.202100300r
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3
Characterization of Tumor Blood Vasculature Expression of Human Invasive Bladder Cancer by Laser Capture Microdissection and Transcriptional Profiling
Autor: Michael Detmar, Vivianne I. Otto, Filip Roudnicky, Cédric Poyet, Lorenz Buser, Peter J. Wild, Karim Saba
Publikováno v: The American journal of pathology. 190(9)
Tumor-associated blood vessels differ from normal vessels and play key roles in tumor progression. We aimed to identify biomolecules that are expressed differentially in human bladder cancer-associated blood vessels to find novel biomarkers and mecha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1f99cb163ffaceacea4ccd35efb5ca
https://pubmed.ncbi.nlm.nih.gov/32585158
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4
Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels
Autor: Susanna Poghosyan, Giorgia Vella, Samia B. Bachmann, Michael Detmar, Jay W. Shin, Simon Schwager, Sun Young Yoon, Cédric Poyet, Sinem Karaman, Vivianne I. Otto, Filip Roudnicky
Publikováno v: Oncogene
ResearcherID
Oncogene, 37 (19)
Thrombospondin-2 (TSP2) is an anti-angiogenic matricellular protein that inhibits tumor growth and angiogenesis. Tumor-associated blood vascular endothelial cells (BECs) were isolated from human invasive bladder cancers and from matched normal bladde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c51437872c9fd7df757117ee10e5391
http://europepmc.org/articles/PMC5945577
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5
High expression of insulin receptor on tumour-associated blood vessels in invasive bladder cancer predicts poor overall and progression-free survival
Autor: Vivianne I. Otto, Dave Tang, Lothar C. Dieterich, Cédric Poyet, Peter Camenzind, Lorenz Buser, Chien Hsien Ho, Peter J. Wild, Filip Roudnicky, Michael Detmar
Publikováno v: The Journal of Pathology. 242:193-205
Bladder cancer is a frequently recurring disease with a very poor prognosis once progressed to invasive stages, and tumour-associated blood vessels play a crucial role in this process. In order to identify novel biomarkers associated with progression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fda0f60231543b31e910c1f74293ff1
https://doi.org/10.1002/path.4892
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6
Mutation of Threonine 34 in Mouse Podoplanin-Fc Reduces CLEC-2 Binding and Toxicity in Vivo While Retaining Anti-lymphangiogenic Activity
Autor: Lu Chen, Alexandra Michaela Ochsenbein, Don Yuen, Vivianne I. Otto, Roberta Bianchi, Eliane Fischer, Michael Detmar, Ellen Ernst
Publikováno v: Journal of Biological Chemistry. 289:21016-21027
The lymphatic system plays an important role in cancer metastasis and inhibition of lymphangiogenesis could be valuable in fighting cancer dissemination. Podoplanin (Pdpn) is a small, transmembrane glycoprotein expressed on the surface of lymphatic e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c52f1f3519f6a9f197f31544506ef08
https://doi.org/10.1074/jbc.m114.550525
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7
Guest Editorial: Critical Thinking in Education and Research—Why and How?
Autor: Gerd Folkers, Norman Sieroka, Vivianne I. Otto
Publikováno v: Angewandte Chemie International Edition. 57:16574-16575
"A responsible scientist is able to step back, critically reflect on his or her own doings, and also explain them to a wider audience. Critical thinking includes the ability to talk to people working in other areas, as well as the broader public. It
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a48a33d15ad66ad93fcb71e4feaf2c
https://doi.org/10.1002/anie.201810397
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9
High expression of insulin receptor on tumour-associated blood vessels in invasive bladder cancer predicts poor overall and progression-free survival
Autor: Filip, Roudnicky, Lothar C, Dieterich, Cedric, Poyet, Lorenz, Buser, Peter, Wild, Dave, Tang, Peter, Camenzind, Chien Hsien, Ho, Vivianne I, Otto, Michael, Detmar
Publikováno v: The Journal of pathology. 242(2)
Bladder cancer is a frequently recurring disease with a very poor prognosis once progressed to invasive stages, and tumour-associated blood vessels play a crucial role in this process. In order to identify novel biomarkers associated with progression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ef775656562bfe0c227c02b3b322755
https://pubmed.ncbi.nlm.nih.gov/28295307
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10
Swiss Feline Cancer Registry 1965-2008: The influence of sex, breed and age on tumour types and tumour locations
Autor: Kay W. Axhausen, Andreas Pospischil, Sara Irina Fabrikant, Vivianne I. Otto, Gerd Folkers, Ramona Graf, Michael Hässig, Gianluca Boo, Dorette Meier, Katrin Grüntzig, M. Welle, Franco Guscetti
Publikováno v: Journal of Comparative Pathology, 154 (2-3)
Journal of Comparative Pathology
Graf, R; Grüntzig, K; Boo, G; Axhausen, K W; Fabrikant, S; Welle, Monika Maria; Meier, D; Guscetti, F; Folkers, G; Otto, V; Pospischil, A (2016). Swiss Feline Cancer Registry 1965-2008: the Influence of Sex, Breed and Age on Tumour Types and Tumour Locations. Journal of comparative pathology, 154(2-3), pp. 195-210. Elsevier 10.1016/j.jcpa.2016.01.008
SummaryCancer registries are valuable sources for epidemiological research investigating risk factors underlying different types of cancer incidence. The present study is based on the Swiss Feline Cancer Registry that comprises 51,322 feline patient
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887b04665adede37ad7d90d8a226e16b
https://eprints.soton.ac.uk/430220/
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