Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Vivianna M, Van Deerlin"'
Autor:
Cheryl E. G. Leyns, Alice Prigent, Brenna Beezhold, Lihang Yao, Nathan G. Hatcher, Peining Tao, John Kang, EunRan Suh, Vivianna M. Van Deerlin, John Q. Trojanowski, Virginia M. Y. Lee, Matthew E. Kennedy, Matthew J. Fell, Michael X. Henderson
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are progressive neurodegenerative diseases characterized by the accumulation of misfolded α-synuclein in the form of Lewy pathology. While most cases are sporadic, there are rar
Externí odkaz:
https://doaj.org/article/ffdac8823595475f8729dc4c771b2777
Autor:
Peter P. Reese, MD, PhD, Joshua M. Diamond, MD, MSCE, David S. Goldberg, MD, MSCE, Vishnu Potluri, MD, MPH, Stacey Prenner, MD, Emily A. Blumberg, MD, Vivianna M. Van Deerlin, MD, PhD, K. Rajender Reddy, MD, Heather Mentch, MBE, Richard Hasz, MFS, CPTC, Ashley Woodards, MPH, Caren Gentile, MS, Jennifer Smith, BS, Christian Bermudez, MD, Maria M. Crespo, MD
Publikováno v:
Transplantation Direct, Vol 9, Iss 7, p e1504 (2023)
Background. SHELTER is a trial of transplanting lungs from deceased donors with hepatitis C virus (HCV) infection into HCV-negative candidates (sponsor: Merck; NCT03724149). Few trials have reported outcomes using thoracic organs from HCV-RNA+ donors
Externí odkaz:
https://doaj.org/article/fc42ce99f44c427a9839198da701431d
Autor:
Daniel Weintraub, Marijan Posavi, Pierre Fontanillas, Thomas F. Tropea, Eugenia Mamikonyan, Eunran Suh, John Q. Trojanowski, Paul Cannon, Vivianna M. Van Deerlin, andMe Research Team, Alice S. Chen‐Plotkin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 7, Pp 936-949 (2022)
Abstract Objective To develop a clinico‐genetic predictor of impulse control disorder (ICD) risk in Parkinson's disease (PD). Methods In 5770 individuals from three PD cohorts (the 23andMe, Inc.; the University of Pennsylvania [UPenn]; and the Park
Externí odkaz:
https://doaj.org/article/39bf7dd46847460688de1fbf2db005c3
Autor:
Tuancheng Feng, Lin Luan, Isabel Iscol Katz, Mohammed Ullah, Vivianna M. Van Deerlin, John Q. Trojanowski, Edward B. Lee, Fenghua Hu
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract TMEM106B, a type II lysosomal transmembrane protein, has recently been associated with brain aging, hypomyelinating leukodystrophy, frontotemporal lobar degeneration (FTLD) and several other brain disorders. TMEM106B is critical for proper l
Externí odkaz:
https://doaj.org/article/5dfee66abaa3451cb8b5dd0293af678e
Autor:
Lucia A. A. Giannini, Claire Peterson, Daniel Ohm, Sharon X. Xie, Corey T. McMillan, Katya Raskovsky, Lauren Massimo, EunRah Suh, Vivianna M. Van Deerlin, David A. Wolk, John Q. Trojanowski, Edward B. Lee, Murray Grossman, David J. Irwin
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Frontotemporal lobar degeneration proteinopathies with tau inclusions (FTLD-Tau) or TDP-43 inclusions (FTLD-TDP) are associated with clinically similar phenotypes. However, these disparate proteinopathies likely differ in cellular severity a
Externí odkaz:
https://doaj.org/article/e790d35cc6d442619b35c3baddb26f2e
Autor:
Meghan E. Sise, Ian A. Strohbehn, Donald F. Chute, Jenna Gustafson, Vivianna M. Van Deerlin, Jennifer R. Smith, Caren Gentile, David Wojciechowski, Winfred W. Williams, Nahel Elias, Raymond T. Chung
Publikováno v:
Kidney International Reports, Vol 5, Iss 4, Pp 459-467 (2020)
Introduction: Long wait times for kidney transplants have prompted investigation into strategies to decrease the discarding of potentially viable organs. Recent reports suggest that kidneys from hepatitis C virus (HCV)−infected donors may be transp
Externí odkaz:
https://doaj.org/article/617d7d9c7f55495e84650b8744f76d64
Autor:
Jonathan Li, Ryan G. Lim, Julia A. Kaye, Victoria Dardov, Alyssa N. Coyne, Jie Wu, Pamela Milani, Andrew Cheng, Terri G. Thompson, Loren Ornelas, Aaron Frank, Miriam Adam, Maria G. Banuelos, Malcolm Casale, Veerle Cox, Renan Escalante-Chong, J. Gavin Daigle, Emilda Gomez, Lindsey Hayes, Ronald Holewenski, Susan Lei, Alex Lenail, Leandro Lima, Berhan Mandefro, Andrea Matlock, Lindsay Panther, Natasha Leanna Patel-Murray, Jacqueline Pham, Divya Ramamoorthy, Karen Sachs, Brandon Shelley, Jennifer Stocksdale, Hannah Trost, Mark Wilhelm, Vidya Venkatraman, Brook T. Wassie, Stacia Wyman, Stephanie Yang, Jennifer E. Van Eyk, Thomas E. Lloyd, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D. Rothstein, Dhruv Sareen, Clive N. Svendsen, Leslie M. Thompson, Hemali Phatnani, PhD, Justin Kwan, MD, Dhruv Sareen, PhD, James R. Broach, PhD, Zachary Simmons, MD, Ximena Arcila-Londono, MD, Edward B. Lee, MD, PhD, Vivianna M. Van Deerlin, MD, PhD, Neil A. Shneider, MD, PhD, Ernest Fraenkel, PhD, Lyle W. Ostrow, MD, PhD, Frank Baas, MD, PhD, Noah Zaitlen, PhD, James D. Berry, MD, MPH, Andrea Malaspina, MD, PhD, Pietro Fratta, MD, PhD, Gregory A. Cox, PhD, Leslie M. Thompson, PhD, Steve Finkbeiner, MD, PhD, Efthimios Dardiotis, MD, PhD, Timothy M. Miller, MD, PhD, Siddharthan Chandran, PhD, Suvankar Pal, MD, Eran Hornstein, MD, PhD, Daniel J. MacGowan, MD, Terry Heiman-Patterson, MD, Molly G. Hammell, PhD, Nikolaos.A. Patsopoulos, MD, PhD, Oleg Butovsky, PhD, Joshua Dubnau, PhD, Avindra Nath, MD, Robert Bowser, PhD, Matt Harms, MD, Mary Poss, DVM, PhD, Jennifer Phillips-Cremins, PhD, John Crary, MD, PhD, Nazem Atassi, MD, Dale J. Lange, MD, Darius J. Adams, MD, Leonidas Stefanis, MD, PhD, Marc Gotkine, MD, Robert H. Baloh, MD. PhD, Suma Babu, MBBS, MPH, Towfique Raj, PhD, Sabrina Paganoni, MD, PhD, Ophir Shalem, PhD, Colin Smith, MD, Bin Zhang, PhD, Brent Harris, MD, PhD, Iris Broce, PhD, Vivian Drory, MD, John Ravits, MD, Corey McMillan, PhD, Vilas Menon, PhD, Lani Wu, PhD, Steven Altschuler, PhD
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103221- (2021)
Summary: Neurodegenerative diseases are challenging for systems biology because of the lack of reliable animal models or patient samples at early disease stages. Induced pluripotent stem cells (iPSCs) could address these challenges. We investigated D
Externí odkaz:
https://doaj.org/article/b0aa201abf104ba08a6430dac01837c5
Autor:
Benjamin J. Kim, Murray Grossman, Tomas S. Aleman, Delu Song, Katheryn A. Q. Cousins, Corey T. McMillan, Adrienne Saludades, Yinxi Yu, Edward B. Lee, David Wolk, Vivianna M. Van Deerlin, Leslie M. Shaw, Gui-Shuang Ying, David J. Irwin
Publikováno v:
Neurobiology of Aging. 125:74-82
Autor:
John L Robinson, Sharon X Xie, Daniel R Baer, EunRan Suh, Vivianna M Van Deerlin, Nicholas J Loh, David J Irwin, Corey T McMillan, David A Wolk, Alice Chen-Plotkin, Daniel Weintraub, Theresa Schuck, Virginia M Y Lee, John Q Trojanowski, Edward B Lee
Publikováno v:
Brain. 146:2557-2569
Pathologies that are causative for neurodegenerative disease (ND) are also frequently present in unimpaired, older individuals. In this retrospective study of 1647 autopsied individuals, we report the incidence of 10 pathologies across ND and normal
Autor:
Ernest J. Nelson, Maria A. Gubbiotti, Alicia M. Carlin, MacLean P. Nasrallah, Vivianna M. Van Deerlin, Sarah E. Herlihy
Publikováno v:
Molecular Diagnosis & Therapy. 27:371-381