Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Viviane Ponath"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103045- (2024)
Summary: The unbiased identification of less-abundant transcription factors, which direct the expression of a target gene, is technically challenging. Here, we present a protocol to analyze the locus-specific chromatin-regulating proteome using in si
Externí odkaz:
https://doaj.org/article/ea73670d5b9343d49da4cc19ec64b089
Autor:
Evangelos Pavlakis, Michelle Neumann, Nastasja Merle, Ronja Wieboldt, Michael Wanzel, Viviane Ponath, Elke Pogge von Strandmann, Sabrina Elmshäuser, Thorsten Stiewe
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract Background TP53, encoding the tumor suppressor p53, is frequently mutated in various cancers, producing mutant p53 proteins (mutp53) which can exhibit neomorphic, gain-of-function properties. The latter transform p53 into an oncoprotein that
Externí odkaz:
https://doaj.org/article/4196caed645b473fadaf09c6ecb0eca3
Autor:
Reem Alkhayer, Viviane Ponath, Miriam Frech, Till Adhikary, Johannes Graumann, Andreas Neubauer, Elke Pogge von Strandmann
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract The immunoreceptor NKG2D, which is expressed on NK cells and T cell subsets is critically involved in tumor immune surveillance. This applies in particular to acute myeloid leukemia (AML), which evades immune detection by downregulation of N
Externí odkaz:
https://doaj.org/article/dc6b4274aced429fa28f5022f9dff929
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Despite the frequent use of ionising radiation (IR) in therapy and diagnostics and the unavoidable exposure to external radiation sources, our knowledge regarding the radiosensitivity of human blood cell populations is limited and published
Externí odkaz:
https://doaj.org/article/5f553cd3447e4cbc8dd6189dbab2760a
Autor:
Esther López, Federica Marinaro, María de los Ángeles de Pedro, Francisco Miguel Sánchez-Margallo, María Gómez-Serrano, Viviane Ponath, Elke Pogge von Strandmann, Inmaculada Jorge, Jesús Vázquez, Luis Miguel Fernández-Pereira, Verónica Crisóstomo, Verónica Álvarez, Javier G. Casado
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Experimental data demonstrated that the regenerative potential and immunomodulatory capacity of cardiosphere-derived cells (CDCs) is mediated by paracrine mechanisms. In this process, extracellular vesicles derived from CDCs (EV-CDCs) are key mediato
Externí odkaz:
https://doaj.org/article/5ddda2a367d0466ab659b4bc77300f66
Autor:
Viviane Ponath, Bernd Kaina
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170347 (2017)
Monocytes and their descendants, macrophages, play a key role in the defence against pathogens. They also contribute to the pathogenesis of inflammatory diseases. Therefore, a mechanism maintaining a balance in the monocyte/macrophage population must
Externí odkaz:
https://doaj.org/article/0ccfe3466c9a4d119d1cfc2f665c8493
Autor:
María Gómez-Serrano, Andrea Nist, Silke Reinartz, Annika Unger, Tim Bieringer, Raimund Dietze, Viviane Ponath, Sabine Müller-Brüsselbach, Elke Pogge von Strandmann, Mohamad K Hammoud, Christian Preußer, Johannes Graumann, Thorsten Stiewe, Anna M. Sokol, Florian Finkernagel, Rolf Müller
Publikováno v:
Theranostics
Arachidonic acid (AA) is a polyunsaturated fatty acid present at high concentrations in the ovarian cancer (OC) microenvironment and associated with a poor clinical outcome. In the present study, we have unraveled a potential link between AA and macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881da6abed20288914a88a7399c57ea7
https://doi.org/10.7150/thno.52442
https://doi.org/10.7150/thno.52442
Autor:
Reem Al Khayer, Viviane Ponath, Elke Pogge von Strandmann, Andreas Neubauer, Cornelia Brendel, Mathis Bittermann, Miriam Frech
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 2857, p 2857 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 2857, p 2857 (2020)
Drugs targeting epigenetic mechanisms such as histone deacetylase inhibitors (HDACi) suppress tumor growth. HDACi also induce the expression of ligands for the cytotoxicity receptor NKG2D rendering tumors more susceptible to natural killer (NK) cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af99ef3df1cc21e17233f45654fa0d5
Publikováno v:
Journal of Innate Immunity. 11:74-85
In previous studies, we showed impaired DNA repair in human monocytes. Here, we addressed the question of whether human neutrophilic granulocytes that arise from the same precursor as monocytes exhibit a similar phenotype and are impaired in repairin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60ad11c1572312a151d1ba79cac6b41
https://doi.org/10.1159/000492678
https://doi.org/10.1159/000492678
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 3362, p 3362 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 3362, p 3362 (2021)
Adipose tissue and its crosstalk with other organs plays an essential role in the metabolic homeostasis of the entire body. Alteration of this communication (i.e., due to obesity) is related to the development of several comorbidities including type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b82a4721972ce0466634cf92a07e9a
https://doi.org/10.3390/ijms22073362
https://doi.org/10.3390/ijms22073362