Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Viviane Klingel"'
Autor:
Sabrina Adam, Julia Bräcker, Viviane Klingel, Bernd Osteresch, Nicole E. Radde, Jens Brockmeyer, Pavel Bashtrykov, Albert Jeltsch
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Sabrina Adam et al. use a deep enzymology method to study the effect of neighboring DNA sequence variation on the in vitro activity of Tet1 and Tet2. Their results suggest that flanking sequences could represent an important parameter that influences
Externí odkaz:
https://doaj.org/article/53caa262787a41d4b84543d2f7d4ab38
Publikováno v:
The FEBS Journal. 290:2115-2126
In previous work, we have developed a DNA methylation-based epigenetic memory system that operates in Escherichia coli to detect environmental signals, trigger a phenotypic switch of the cells and store the information in DNA methylation. The system
Publikováno v:
Nucleic Acids Research.
The specificity of DNMT1 for hemimethylated DNA is a central feature for the inheritance of DNA methylation. We investigated this property in competitive methylation kinetics using hemimethylated (HM), hemihydroxymethylated (OH) and unmethylated (UM)
Publikováno v:
IFAC-PapersOnLine. 55:86-91
Author response for 'Reversible switching and stability of the epigenetic memory system in bacteria'
Autor:
null Dimitri Graf, null Laura Laistner, null Viviane Klingel, null Nicole E. Radde, null Sara Weirich, null Albert Jeltsch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7842f4cad149b14891ec3cdc9db1d976
https://doi.org/10.1111/febs.16690/v2/response1
https://doi.org/10.1111/febs.16690/v2/response1
Publikováno v:
The FEBS Journal. 288:5692-5707
In recent years, epigenetic memory systems have been developed based on DNA methylation and positive feedback systems. Achieving a robust design for these systems is generally a challenging and multi-factorial task. We developed and validated a novel
Autor:
Aidin R. Balo, Oliver P. Ernst, Wei-Lin Ou, A. Kuo, Craig M. Ogata, Jana Broecker, David J. Kissick, Viviane Klingel
Publikováno v:
Crystal Growth & Design
In recent years, in situ data collection has been a major focus of progress in protein crystallography. Here, we introduce the Mylar in situ method using Mylar-based sandwich plates that are inexpensive, easy to make and handle, and show significantl
Autor:
Vadim Cherezov, Ming-Yue Lee, David J. Kissick, Viviane Klingel, Takefumi Morizumi, S. Xu, Jana Broecker, Oleg Makarov, Andrii Ishchenko, Craig M. Ogata, Wei-Lin Ou, Oliver P. Ernst, A. Kuo
Publikováno v:
Nature protocols. 13(2)
Protein crystallography has significantly advanced in recent years, with in situ data collection, in which crystals are placed in the X-ray beam within their growth medium, being a major point of focus. In situ methods eliminate the need to harvest c
Publikováno v:
Biophysical Journal. 110(3)
In the last decade, crystallisation of membrane proteins in lipidic cubic phases (LCP; in meso) boosted the numbers and resolution of membrane-protein structures. However, membrane-protein crystals are usually small and notoriously difficult to harve