Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Viviane Aline Oliveira Silva"'
Autor:
Taís Bacelar Sacramento de Araújo, Raphael Luís Rocha Nogueira, Leonardo de Oliveira Siquara da Rocha, Iasmin Nogueira Bastos, Rosane Borges Dias, Bruno Solano De Freitas Souza, Daniel William Lambert, Ricardo D. Coletta, Viviane Aline Oliveira Silva, Clarissa A. Gurgel Rocha
Publikováno v:
SLAS Discovery, Vol 29, Iss 4, Pp 100158- (2024)
3D in vitro systems offer advantages over the shortcomings of two-dimensional models by simulating the morphological and functional features of in vivo-like environments, such as cell-cell and cell-extracellular matrix interactions, as well as the co
Externí odkaz:
https://doaj.org/article/d85631babf104765a0217f2302f5a181
Autor:
Nathália Cristina Campanella, Izabela Natalia Faria Gomes, Ana Laura Vieira Alves, Leticia Ferro Leal, Adriane Feijó Evangelista, Marcela Nunes Rosa, Matias Eliseo Melendez, Viviane Aline Oliveira Silva, Richard Lucas Konichi Dias, Lucas Faria Abrahão-Machado, Iara Santana, Olga Martinho, Denise Peixoto Guimarães, Vitor Marcel Faça, Rui Manuel Reis
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Gastrointestinal stromal tumors (GIST) represent a significant clinical challenge due to their metastatic potential and limited treatment options. Raf kinase inhibitor protein (RKIP), a suppressor of the MAPK signaling pathway, is
Externí odkaz:
https://doaj.org/article/ce7c3f26427e4e2f902096b56cc1bf21
Autor:
Lucas Bravo Perina, Izabela Natalia Faria Gomes, Ana Rúbia Alcantara Pelloso, Viviane Aline Oliveira Silva, Lidia Maria Rebolho Batista Arantes, Matias Eliseo Melendez
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Knowledge on the molecular and clinical characteristics of head and neck squamous cell carcinoma (HNSCC) is vast. However, an effective therapy that increases the life expectancy of these patients, with a 5-year overall survival of 50%, is s
Externí odkaz:
https://doaj.org/article/d14b1f3e30bf481fafeb52ea7c362b0b
Autor:
Ana Laura Vieira Alves, Angela Margarida Costa, Olga Martinho, Vinicius Duval da Silva, Peter Jordan, Viviane Aline Oliveira Silva, Rui Manuel Reis
Publikováno v:
Cells, Vol 13, Iss 14, p 1219 (2024)
Error in Figure [...]
Externí odkaz:
https://doaj.org/article/c1546ab38bf842b1ad8e8203ebe32984
Autor:
Raphael Luís Rocha Nogueira, Taís Bacelar Sacramento de Araújo, Ludmila Faro Valverde, Viviane Aline Oliveira Silva, Bruno Raphael Ribeiro Cavalcante, Erik Aranha Rossi, Kyan James Allahdadi, Mitermayer Galvão dos Reis, Thiago Almeida Pereira, Ricardo D. Coletta, Daniel Pereira Bezerra, Bruno Solano de Freitas Souza, Rosane Borges Dias, Clarissa A. Gurgel Rocha
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3293 (2022)
Given the lack of advances in Oral Squamous Cell Carcinoma (OSCC) therapy in recent years, pharmacological strategies to block OSCC-related signaling pathways have gained prominence. The present study aimed to evaluate the therapeutic potential of Ar
Externí odkaz:
https://doaj.org/article/9e8751c72f074bf4a195f06ed922b9d5
Autor:
Izabela N. F. Gomes, Renato J. da Silva-Oliveira, Luciane Sussuchi da Silva, Olga Martinho, Adriane F. Evangelista, André van Helvoort Lengert, Letícia Ferro Leal, Viviane Aline Oliveira Silva, Stéphanie Piancenti dos Santos, Flávia Caroline Nascimento, André Lopes Carvalho, Rui Manuel Reis
Publikováno v:
Cells, Vol 11, Iss 1, p 154 (2022)
Cetuximab is the sole anti-EGFR monoclonal antibody that is FDA approved to treat head and neck squamous cell carcinoma (HNSCC). However, no predictive biomarkers of cetuximab response are known for HNSCC. Herein, we address the molecular mechanisms
Externí odkaz:
https://doaj.org/article/c72f8685c0814c25b7bf993a42594fde
Autor:
Leidiana Rocha dos Reis, Marcela Tavares Luiz, Rafael M Sábio, Gabriel Davi Marena, Leonardo Delello Di Filippo, Jonatas Lobato Duarte, Ligia de Souza Fernandes, Victor H Sousa Araújo, Viviane Aline Oliveira Silva, Marlus Chorilli
Publikováno v:
Nanomedicine.
Aims: The development of rapamycin (RAP) and resveratrol (RSV) coloaded liposomes (RAP-RSV-LIP) for breast cancer therapy. Materials & methods: Liposomes were prepared using a high-pressure homogenization technique and evaluated according to their ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::246ab26d0f9382efa8d10a248853d9ba
https://doi.org/10.2217/nnm-2022-0227
https://doi.org/10.2217/nnm-2022-0227
Autor:
Matias Eliseo Melendez, Edenir Inêz Palmero, Cíntia Regina Niederauer Ramos, Renato José Silva Oliveira, Marcela Nunes Rosa, Ariane Stéfani Pereira, Renata Barbosa Vahia de Abreu, Andre van Helvoort Lengert, Rui Manuel Reis, Viviane Aline Oliveira Silva
Publikováno v:
Current Cancer Drug Targets. 23
BACKGROUND: Breast and ovarian tumors with pathogenic variants in BRCA1 or BRCA2 genes are more sensitive to poly (ADP-ribose) polymerase inhibitors (PARPi) treatment than wild-type tumors. Pathogenic variants in non-BRCA1/2 homologous recombination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d58b911fdf1435652fa799deb21772
https://doi.org/10.2174/1568009623666230418101511
https://doi.org/10.2174/1568009623666230418101511
Autor:
Weder Pereira de Menezes, Viviane Aline Oliveira Silva, Izabela Natália Faria Gomes, Marcela Nunes Rosa, Maria Luisa Corcoll Spina, Adriana Cruvinel Carloni, Ana Laura Vieira Alves, Matias Melendez, Gisele Caravina Almeida, Luciane Sussuchi da Silva, Carlos Clara, Isabela Werneck da Cunha, Glaucia Noeli Maroso Hajj, Chris Jones, Lucas Tadeu Bidinotto, Rui Manuel Reis
Publikováno v:
Cells, Vol 9, Iss 2, p 492 (2020)
The 5’-methylthioadenosine phosphorylase (MTAP) gene is located in the chromosomal region 9p21. MTAP deletion is a frequent event in a wide variety of human cancers; however, its biological role in tumorigenesis remains unclear. The purpose of this
Externí odkaz:
https://doaj.org/article/ca517d8f93004ddca5f095d3f8954f4c
Autor:
Ana Laura Vieira Alves, Angela Margarida Costa, Olga Martinho, Vinicius Duval da Silva, Peter Jordan, Viviane Aline Oliveira Silva, Rui Manuel Reis
Publikováno v:
Cells, Vol 9, Iss 2, p 485 (2020)
Autophagy is a cell-survival pathway with dual role in tumorigenesis, promoting either tumor survival or tumor death. WNK2 gene, a member of the WNK (with no lysine (K)) subfamily, acts as a tumor suppressor gene in gliomas, regulating cell migration
Externí odkaz:
https://doaj.org/article/9cd5209aac2444cca7788ea4e299ea15