Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Viviana Mannella"'
Autor:
Viviana Mannella, Kira Boehm, Suheyla Celik, Tasnim Ali, Amnah N. Mirza, Mariam El Hasnaouy, Andreas Kaffa, Yanshuang Lyu, Donya Kafaei Golahmadi, Irene M. Leigh, Daniele Bergamaschi, Catherine A. Harwood, Tania Maffucci
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3567 (2021)
Cutaneous squamous cell carcinomas (cSCCs) account for about 20% of keratinocyte carcinomas, the most common cancer in the UK. Therapeutic options for cSCC patients who develop metastasis are limited and a better understanding of the biochemical path
Externí odkaz:
https://doaj.org/article/d1735ca0cd714d07acbd88891bfd7116
Autor:
Sakinah Hassan, Karin J. Purdie, Jun Wang, Catherine A. Harwood, Charlotte M. Proby, Celine Pourreyron, Nikol Mladkova, Ai Nagano, Sandeep Dhayade, Dimitris Athineos, Matthew Caley, Viviana Mannella, Karen Blyth, Gareth J. Inman, Irene M. Leigh
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3428 (2019)
Background: Cutaneous squamous cell carcinoma (cSCC) incidence continues to rise with increasing morbidity and mortality, with limited treatment options for advanced disease. Future improvements in targeted therapy will rely on advances in genomic/tr
Externí odkaz:
https://doaj.org/article/98119bebc7214a0dae59214416994d70
Autor:
Daniele Bergamaschi, Catherine A. Harwood, Rubeta N. Matin, Christian Posch, Andrea Maurichi, Monica Rodolfo, Elisabetta Vergani, Giovanna Chiorino, Maria Scatolini, Tania Maffucci, Tiffanie-Marie Borg, Luke Gammon, Viviana Mannella, Lucia Fraile Garcia, Ankit Patel
Targeting the MAPK pathway by combined inhibition of BRAF and MEK has increased overall survival in advanced BRAF-mutant melanoma in both therapeutic and adjuvant clinical settings. However, a significant proportion of tumors develop acquired resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7bd3b6ee6e425241bf7d6fa8e37e16
https://doi.org/10.1158/0008-5472.c.6511894.v1
https://doi.org/10.1158/0008-5472.c.6511894.v1
Autor:
Daniele Bergamaschi, Catherine A. Harwood, Rubeta N. Matin, Christian Posch, Andrea Maurichi, Monica Rodolfo, Elisabetta Vergani, Giovanna Chiorino, Maria Scatolini, Tania Maffucci, Tiffanie-Marie Borg, Luke Gammon, Viviana Mannella, Lucia Fraile Garcia, Ankit Patel
Supplemental Information includes 5 Supplementary figures and legends: Figure S1: Correlation of p63 expression and BRAF/NRAS mutational status in melanoma and characterization of MAPKi resistant melanoma cell lines. Figure S2: p63 upregulation in MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026c6b2d1a37fbe64e024626f6c15097
https://doi.org/10.1158/0008-5472.22424905
https://doi.org/10.1158/0008-5472.22424905
Autor:
Giovanna Chiorino, Monica Rodolfo, Tania Maffucci, Daniele Bergamaschi, Lucia Fraile Garcia, Christian Posch, Elisabetta Vergani, Catherine A. Harwood, Viviana Mannella, Tiffanie-Marie Borg, Ankit Kumar Patel, Andrea Maurichi, Luke Gammon, Maria Scatolini, Rubeta Nishat Matin
Publikováno v:
Cancer research. 80(12)
Targeting the MAPK pathway by combined inhibition of BRAF and MEK has increased overall survival in advanced BRAF-mutant melanoma in both therapeutic and adjuvant clinical settings. However, a significant proportion of tumors develop acquired resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54d74ec9ad2fb13d2ce515d9138937a
https://pubmed.ncbi.nlm.nih.gov/32291316
https://pubmed.ncbi.nlm.nih.gov/32291316
Autor:
Ai Nagano, Gareth J. Inman, Viviana Mannella, Dimitris Athineos, Sakinah Hassan, Irene M. Leigh, Celine Pourreyron, Karin J. Purdie, Charlotte M. Proby, Sandeep Dhayade, Nikol Mladkova, Catherine A. Harwood, M. Caley, Jun Wang, Karen Blyth
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3428 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 14
International Journal of Molecular Sciences
Volume 20
Issue 14
Background: Cutaneous squamous cell carcinoma (cSCC) incidence continues to rise with increasing morbidity and mortality, with limited treatment options for advanced disease. Future improvements in targeted therapy will rely on advances in genomic/tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff76627ae66485bab9f7ba9b6b5b4329
https://www.mdpi.com/1422-0067/20/14/3428
https://www.mdpi.com/1422-0067/20/14/3428
Autor:
Karin J. Purdie, Irene M. Leigh, Michael P. Philpott, S. Asher, Viviana Mannella, Rosalind F. Hannen
Publikováno v:
Journal of Investigative Dermatology. 137:S215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8f1c1157c9a6f092924a6ec641ffaa
https://doi.org/10.1016/j.jid.2017.07.441
https://doi.org/10.1016/j.jid.2017.07.441