Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion.

Autor: Giuseppe Cortone, Ge Zheng, Pasquale Pensieri, Viviana Chiappetta, Rosarita Tatè, Eva Malacaria, Pietro Pichierri, Hongtao Yu, Francesca M Pisani

Publikováno v: PLoS Genetics, Vol 14, Iss 10, p e1007622 (2018)

Establishment of sister chromatid cohesion is coupled to DNA replication, but the underlying molecular mechanisms are incompletely understood. DDX11 (also named ChlR1) is a super-family 2 Fe-S cluster-containing DNA helicase implicated in Warsaw brea

Externí odkaz: https://doaj.org/article/1f67aff65e4e476eaab083559b9c04bc

Human blastocyst spontaneous collapse is associated with worse morphological quality and higher degeneration and aneuploidy rates: a comprehensive analysis standardized through artificial intelligence

Autor: Danilo Cimadomo, Anabella Marconetto, Samuele Trio, Viviana Chiappetta, Federica Innocenti, Laura Albricci, Itay Erlich, Assaf Ben-Meir, Iris Har-Vardi, Ben Kantor, Anat Sakov, Giovanni Coticchio, Andrea Borini, Filippo Maria Ubaldi, Laura Rienzi

Publikováno v: Human reproduction (Oxford, England). 37(10)

STUDY QUESTION What are the factors associated with human blastocyst spontaneous collapse and the consequences of this event? SUMMARY ANSWER Approximately 50% of blastocysts collapsed, especially when non-viable, morphologically poor and/or aneuploid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f52de319eb0fa04ed39800933b8d3fa
https://pubmed.ncbi.nlm.nih.gov/35939563

Genomic integrity and mitochondrial metabolism defects in Warsaw syndrome cells: a comparison with Fanconi anemia

Autor: Luisa M. R. Napolitano, Martina Moretti, Silvia Ravera, Viviana Chiappetta, Giuseppe Cortone, Nicoletta Zini, Barbara Crescenzi, Flavio Faletra, Roberta Bottega, Enrico Cappelli, Francesca M. Pisani, Michela Faleschini, Anna Savoia, Silvia Onesti, Silvia Arniani, Job de Lange, Cristina Mecucci, Fabio Sirchia, Barbara Medagli

Publikováno v: Journal of cellular physiology
236 (2021): 5664–5675. doi:10.1002/jcp.30265
info:cnr-pdr/source/autori:Bottega, Roberta; Ravera, Silvia; Napolitano, Luisa M. R.; Chiappetta, Viviana; Zini, Nicoletta; Crescenzi, Barbara; Arniani, Silvia; Faleschini, Michela; Cortone, Giuseppe; Faletra, Flavio; Medagli, Barbara; Sirchia, Fabio; Moretti, Martina; de Lange, Job; Cappelli, Enrico; Mecucci, Cristina; Onesti, Silvia; Pisani, Francesca M.; Savoia, Anna/titolo:Genomic integrity and mitochondrial metabolism defects in Warsaw syndrome cells: a comparison with Fanconi anemia./doi:10.1002%2Fjcp.30265/rivista:Journal of cellular physiology (Print)/anno:2021/pagina_da:5664/pagina_a:5675/intervallo_pagine:5664–5675/volume:236
Journal of Cellular Physiology, 236(8), 5664-5675. Wiley-Liss Inc.
Bottega, R, Ravera, S, Napolitano, L M R, Chiappetta, V, Zini, N, Crescenzi, B, Arniani, S, Faleschini, M, Cortone, G, Faletra, F, Medagli, B, Sirchia, F, Moretti, M, de Lange, J, Cappelli, E, Mecucci, C, Onesti, S, Pisani, F M & Savoia, A 2021, ' Genomic integrity and mitochondrial metabolism defects in Warsaw syndrome cells : A comparison with Fanconi anemia ', Journal of Cellular Physiology, vol. 236, no. 8, pp. 5664-5675 . https://doi.org/10.1002/jcp.30265

Warsaw breakage syndrome (WABS), is caused by biallelic mutations of DDX11, a gene coding a DNA helicase. We have recently reported two affected sisters, compound heterozygous for a missense (p.Leu836Pro) and a frameshift (p.Lys303Glufs*22) variant.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e23e7b9bc7636c17635216bd2e476fc
https://pubmed.ncbi.nlm.nih.gov/33432587

Predictors of quit attempts and successful quit attempts among individuals with alcohol use disorders in a nationally representative sample

Autor: Roberto Secades-Villa, Carlos Blanco, Viviana Chiappetta, Chelsea Jin, Olaya García-Rodríguez

Publikováno v: Drug and Alcohol Dependence. 141:138-144

Background This study sought to identify predictors of attempting to quit and of successfully quitting alcohol abuse or dependence in the general population. Methods Data were drawn from the National Epidemiologic Survey on Alcohol and Related Condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beaa39a989e673be2c4d592ec725507
https://doi.org/10.1016/j.drugalcdep.2014.05.019

4.56 Prevalence of Anger in the Child Adolescent Inpatient Population With Positive Traumatic Experience and Associated Comorbidities: Performance Improvement Project

Autor: Viviana Chiappetta, Panagiota Korenis, Michelle Kohut, Pankaj Manocha, Aos Mohammed Ameen, Monica Badillo, Muhammad Zeshan, Luisa Gonzalez, Wen Gu

Publikováno v: Journal of the American Academy of Child & Adolescent Psychiatry. 56:S248

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf26040791ebee73c2bd312d15908715
https://doi.org/10.1016/j.jaac.2017.09.272