Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Viviana C. Blank"'
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Akademický článek
A Penicillin Derivative Exerts an Anti-Metastatic Activity in Melanoma Cells Through the Downregulation of Integrin αvβ3 and Wnt/β-Catenin Pathway
Autor: Elizabeth Barrionuevo, Florencia Cayrol, Graciela A. Cremaschi, Patricia G. Cornier, Dora B. Boggián, Carina M. L. Delpiccolo, Ernesto G. Mata, Leonor P. Roguin, Viviana C. Blank
Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
The synthetic triazolylpeptidyl penicillin derivative, named TAP7f, has been previously characterized as an effective antitumor agent in vitro and in vivo against B16-F0 melanoma cells. In this study, we investigated the anti-metastatic potential of
Externí odkaz: https://doaj.org/article/aa779f640d1a4392bc3ab33af106ce02
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3
Contribution of endoplasmic reticulum stress, MAPK and PI3K/Akt pathways to the apoptotic death induced by a penicillin derivative in melanoma cells
Autor: Ernesto G. Mata, Patricia G. Cornier, Juan Manuel Anselmi Relats, Yanina Bellizzi, Florencia Cayrol, Graciela Cremaschi, Carina M. L. Delpiccolo, Viviana C. Blank, Leonor P. Roguin
Publikováno v: Apoptosis. 2022, 27 (1-2)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Bellizzi, Yanina. Universidad de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Facultad de Farmacia y Bioquímica. Laboratorio de Oncología y Transducción de Señales. Instituto de Química y Fisicoquímica Bioló
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d625eef6ed7f95bd0c9f7913b588323
https://doi.org/10.1007/s10495-021-01697-7
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4
Design, synthesis and cytotoxic evaluation of peptoid analogs of an anticancer active triazolylpeptidyl penicillin
Autor: Viviana C. Blank, Elizabeth Barrionuevo, Ernesto G. Mata, Yanina Bellizzi, Leonor P. Roguin, Patricia G. Cornier, Nadia L Martiren
Publikováno v: Future Medicinal Chemistry. 13:1127-1139
Aim: Encouraged by the antitumor activity exhibited by triazolylpeptidyl penicillins, we decided to synthesize and evaluate a library of peptoid analogs. Results: The replacement of the dipeptide unit of the reference compound, TAP7f, was investigate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f579bcb6e605f9fd8109b7438d937e
https://doi.org/10.4155/fmc-2020-0379
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5
Contribution of endoplasmic reticulum stress, MAPK and PI3K/Akt pathways to the apoptotic death induced by a penicillin derivative in melanoma cells
Autor: Yanina, Bellizzi, Juan Manuel, Anselmi Relats, Patricia G, Cornier, Carina M L, Delpiccolo, Ernesto G, Mata, Florencia, Cayrol, Graciela A, Cremaschi, Viviana C, Blank, Leonor P, Roguin
Publikováno v: Apoptosis : an international journal on programmed cell death. 27(1-2)
We have previously examined the in vitro and in vivo antitumor action of TAP7f, a synthetic triazolylpeptidyl penicillin, on murine melanoma cells. In this work, we explored the signal transduction pathways modulated by TAP7f in murine B16-F0 and hum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::496a10638259a770a5f654d8ed09480a
https://pubmed.ncbi.nlm.nih.gov/34773171
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6
Design, synthesis and cytotoxic evaluation of a library of oxadiazole-containing hybrids
Autor: Marianela G. Pizzio, Elizabeth Barrionuevo, Yanina Bellizzi, Dora B. Boggián, Ernesto G. Mata, Viviana C. Blank, Leonor P. Roguin, David L. Roces, Cristian M. Camacho
Publikováno v: RepHipUNR (UNR)
Universidad Nacional de Rosario
instacron:UNR
The development of hybrid compounds led to the discovery of new pharmacologically active agents for some of the most critical diseases, including cancer. Herein, we describe a new series of oxadiazole-containing structures designed by a molecular hyb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a19e7405d24a38acb465e8e25349581
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7
A Penicillin Derivative Exerts an Anti-Metastatic Activity in Melanoma Cells Through the Downregulation of Integrin αvβ3 and Wnt/β-Catenin Pathway
Autor: Carina M. L. Delpiccolo, Leonor P. Roguin, Viviana C. Blank, Ernesto G. Mata, Dora B. Boggián, Patricia G. Cornier, Elizabeth Barrionuevo, Florencia Cayrol, Graciela Cremaschi
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Pharmacology. 2020, 11:127
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
The synthetic triazolylpeptidyl penicillin derivative, named TAP7f, has been previously characterized as an effective antitumor agent in vitro and in vivo against B16-F0 melanoma cells. In this study, we investigated the anti-metastatic potential of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef2db5cbb0c6a8cdcd8d896097d9300
https://www.frontiersin.org/articles/10.3389/fphar.2020.00127/full
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8
A novel penicillin derivative induces antitumor effect in melanoma cells
Autor: Ernesto G. Mata, Carina M. L. Delpiccolo, Dora B. Boggián, Viviana C. Blank, Elsa Zotta, Leonor P. Roguin, Patricia G. Cornier, Yanina Bellizzi
Publikováno v: Anti-Cancer Drugs. 29:416-428
In this study, we explored the in-vitro and in-vivo mechanism of antitumor action of a novel synthetic nonantibiotic triazolylpeptidyl penicillin derivative, named TAP7f, on B16-F0 murine melanoma cells. In-vitro assays showed that TAP7f caused an in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410768ce05562d8d440207c6018a143f
https://doi.org/10.1097/cad.0000000000000611
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9
Nanoclusters of crystallographically aligned nanoparticles for magnetic thermotherapy: aqueous ferrofluid, agarose phantoms and ex vivo melanoma tumour assessment
Autor: M. A. Bab, Alejandro Luis Veiga, S. A. González, Anna Roig, Paula A. Soto, P C Setton-Avruj, M. B. Fernández van Raap, D. F. Coral, Diego Muraca, Viviana C. Blank, G. P. Saracco, Enrique Mario Spinelli, Leonor P. Roguin
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Magnetic hyperthermia is an oncological therapy where magnetic nanostructures, under a radiofrequency field, act as heat transducers increasing tumour temperature and killing cancerous cells. Nanostructure heating efficiency depends both on the field
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f979478a641d006d0207f32f1337d4f
https://doi.org/10.1039/c8nr07453d
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10
2′-Nitroflavone induces apoptosis and modulates mitogen-activated protein kinase pathways in human leukaemia cells
Autor: Viviana C. Blank, Mariano G. Cardenas, Mariel Marder, Leonor P. Roguin
Publikováno v: Anti-Cancer Drugs. 23:815-826
The cytotoxic activity of 2'-nitroflavone was evaluated in different haematological cancer cell lines and its mechanism of action was further studied in HL-60 cells. 2'-Nitroflavone arrested the cell cycle at the G(2)/M phase and induced an apoptotic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb21631e04c6cab7cddb975af3a3cb4
https://doi.org/10.1097/cad.0b013e328353f947
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