Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Vivian Yvonne Shin"'
Autor:
Ava Kwong, Cecilia Yuen Sze Ho, Vivian Yvonne Shin, Chun Hang Au, Tsun-Leung Chan, Edmond Shiu Kwan Ma
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background The popularity of multigene testing increases the probability of identifying variants of uncertain significance (VUS). While accurate variant interpretation enables clinicians to be better informed of the genetic risk of their pat
Externí odkaz:
https://doaj.org/article/7783bc06d4f8473ebd28c6a2080cce23
Autor:
Ava Kwong, Cecilia Yuen Sze Ho, Vivian Yvonne Shin, Chun Hang Au, Wing Pan Luk, Ling Hiu Fung, Tsun‐Leung Chan, Karen Kar Loen Chan, Hextan Yuen Sheung Ngan, Edmond Shiu Kwan Ma
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Background Ovarian and breast cancers are known to have significant genetic components. Considering the differences in the mutation spectrum across ethnicity, it is important to identify hereditary breast and ovarian cancer (HBOC) genes muta
Externí odkaz:
https://doaj.org/article/0824d0fd5fc744bca7f83b5f4a1a44ff
Autor:
Ava Kwong, Vivian Yvonne Shin, Cecilia Y. S. Ho, Chun Hang Au, Thomas P. Slavin, Jeffrey N. Weitzel, Tsun-Leung Chan, Edmond S. K. Ma
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the clinical implication for mutation carriers and their families is si
Externí odkaz:
https://doaj.org/article/00741944e70547149fff3695430a3e4a
Autor:
Jiawei Chen, Vivian Yvonne Shin, John Chi-Wang Ho, Man-Ting Siu, Isabella Wai-Yin Cheuk, Ava Kwong
Publikováno v:
Biomolecules, Vol 10, Iss 5, p 688 (2020)
It is well-established that tumor-associated macrophages (TAMs) play an important role in breast cancer development. Accumulating evidence suggested that human cathelicidin antimicrobial protein (CAMP), which is mainly expressed in host defense cells
Externí odkaz:
https://doaj.org/article/29d98aec1b5d4244a79f494a40006a45
Autor:
Ava Kwong, Cecilia Yuen Sze Ho, Vivian Yvonne Shin, Ada Tsui Lin Ng, Tsun Leung Chan, Edmond Shiu Kwan Ma
Publikováno v:
Breast Cancer Research and Treatment. 198:391-400
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc4d54cc577ec2d814a86d7b14c962fb
https://doi.org/10.1007/s10549-022-06651-y
https://doi.org/10.1007/s10549-022-06651-y
Autor:
Vivian Yvonne Shin, Godfrey Chi-Fung Chan, Clare T. M. Lai, Ronald A. Li, Wendy Keung, Yiu-fai Cheung, Ava Kwong, Daniel K. L. Cheuk, Vivian Wing-yi Li
Publikováno v:
Pediatric Research. 89:1245-1252
BACKGROUND: We investigated whether plasma high-sensitivity cardiac troponin T (hs-cTnT) and circulating heart-associated microRNA (miRs) are increased in children with leukaemias during anthracycline-based chemotherapeutic treatment. METHODS: In vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fbfab903a7b2c839bc03b5474cc4b03
https://doi.org/10.1038/s41390-020-1049-5
https://doi.org/10.1038/s41390-020-1049-5
Autor:
John Chi-Wang, Ho, Jiawei, Chen, Isabella Wai-Yin, Cheuk, Man-Ting, Siu, Vivian Yvonne, Shin, Ava, Kwong
Publikováno v:
Am J Transl Res
MiR-199a-3p was previously predicted to target tumor suppressor gene BRCA1, which has been linked to cancer onset and therapeutic response. In this study, the effects of miR-199a-3p-mediated BRCA1 dysfunction on triple-negative breast cancer (TNBC) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::426959b106bcf4249a2c2049a41965d9
https://pubmed.ncbi.nlm.nih.gov/35422914
https://pubmed.ncbi.nlm.nih.gov/35422914
Autor:
Ava Kwong, Cecilia Yuen Sze Ho, Vivian Yvonne Shin, Chun Hang Au, Tsun-Leung Chan, Edmond Shiu Kwan Ma
Publikováno v:
BMC medical genomics. 15(1)
Background The popularity of multigene testing increases the probability of identifying variants of uncertain significance (VUS). While accurate variant interpretation enables clinicians to be better informed of the genetic risk of their patients, cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aaf4ac70579ac4e185711fad9550224
https://pubmed.ncbi.nlm.nih.gov/35641994
https://pubmed.ncbi.nlm.nih.gov/35641994
Autor:
Ava, Kwong, Isabella Wy, Cheuk, Vivian Yvonne, Shin, Cecilia Ys, Ho, Chun-Hang, Au, Dona Ny, Ho, Elaine Yl, Wong, Stephanie Wy, Yu, Jiawei, Chen, Karen Kl, Chan, Hextan Ys, Ngan, Tsun-Leung, Chan, Edmond Sk, Ma
Publikováno v:
Am J Cancer Res
Targeted therapeutic agents such as poly (ADP-ribose) polymerases (PARP) inhibitors have emerged in treating cancers associated with germline BRCA mutations. Recently studies demonstrated the effectiveness of PARP inhibitors in treating patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a405c342a81777069082f7ef96545535
https://pubmed.ncbi.nlm.nih.gov/33042626
https://pubmed.ncbi.nlm.nih.gov/33042626
Autor:
Yiu-Fai, Cheung, Vivian Wing-Yi, Li, Clare Tik-Man, Lai, Vivian Yvonne, Shin, Wendy, Keung, Daniel Ka-Leung, Cheuk, Ava, Kwong, Ronald Adolphus, Li, Godfrey Chi-Fung, Chan
Publikováno v:
Pediatric research. 89(5)
We investigated whether plasma high-sensitivity cardiac troponin T (hs-cTnT) and circulating heart-associated microRNA (miRs) are increased in children with leukaemias during anthracycline-based chemotherapeutic treatment.In vitro human pluripotent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b99e672cf8688fee8919963493a29afd
https://pubmed.ncbi.nlm.nih.gov/32634817
https://pubmed.ncbi.nlm.nih.gov/32634817