Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Vivian W. Tang"'
Autor:
Vivian W. Tang
Publikováno v:
F1000Research, Vol 7 (2018)
The epithelial lateral membrane plays a central role in the integration of intercellular signals and, by doing so, is a principal determinant in the emerging properties of epithelial tissues. Mechanical force, when applied to the lateral cell–cell
Externí odkaz:
https://doaj.org/article/5baf3e21b73246778416ef969b7c640a
Autor:
Vivian W. Tang
Publikováno v:
Molecular Biology of the Cell
The emergence of collagen I in vertebrates resulted in a dramatic increase in the stiffness of the extracellular environment, supporting long-range force propagation and the development of low-compliant tissues necessary for the development of verteb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e186c63b73783dde77347a1d0204f9
https://doi.org/10.1091/mbc.e19-12-0709
https://doi.org/10.1091/mbc.e19-12-0709
Publikováno v:
Proc Natl Acad Sci U S A
Cadherin-mediated cell-cell adhesion is actin-dependent, but the precise role of actin in maintaining cell-cell adhesion is not fully understood. Actin polymerization-dependent protrusive activity is required to push distally separated cells close en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a9251c72ff4c738e973812564adb52
https://doi.org/10.1073/pnas.1908654117
https://doi.org/10.1073/pnas.1908654117
Publikováno v:
Proc Natl Acad Sci U S A
Cadherins harness the actin cytoskeleton to build cohesive sheets of cells using paradoxically weak bonds, but the molecular mechanisms are poorly understood. In one popular model, actin organizes cadherins into large, micrometer-sized clusters known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b358e7f713798e754537a475e20f32e9
https://pubmed.ncbi.nlm.nih.gov/34099568
https://pubmed.ncbi.nlm.nih.gov/34099568
The apical junction of epithelial cells can generate force to control cell geometry and perform contractile processes while maintaining barrier function and adhesion. Yet, the structural basis for force generation at the apical junction is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec2e682db829f2e3e6d0010f4fcd560
https://doi.org/10.1101/2020.12.30.424702
https://doi.org/10.1101/2020.12.30.424702
Publikováno v:
The Journal of cell biology. 221(5)
The apical junction of epithelial cells can generate force to control cell geometry and perform contractile processes while maintaining barrier function and adhesion. Yet, the structural basis for force generation at the apical junction is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4979fd73ce4003efd589eaa90f93a6
https://pubmed.ncbi.nlm.nih.gov/35416930
https://pubmed.ncbi.nlm.nih.gov/35416930
Cadherins build stable, cohesive sheets of cells using paradoxically weak bonds. Actin is thought to convert weak binding into strong adhesion either by transmitting myosin dependent pulling forces to adhesive junctions or by clustering cadherins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a2ad52f2b2cbd99d352e71785b1fd7
https://doi.org/10.1101/2020.10.12.335489
https://doi.org/10.1101/2020.10.12.335489
Publikováno v:
J Biol Chem
Cofilin is an actin filament severing protein necessary for fast actin turnover dynamics. Coronin and Aip1 promote cofilin-mediated actin filament disassembly, but the mechanism is somewhat controversial. An early model proposed that the combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725dcfcac6f9f86c9aadc23a61b1a321
https://pubmed.ncbi.nlm.nih.gov/32723865
https://pubmed.ncbi.nlm.nih.gov/32723865
Cadherin mediated cell-cell adhesion is actin dependent, but the precise role of actin in maintaining cell-cell adhesion is not fully understood. Actin polymerization-dependent protrusive activity is required to push distally separated cells close en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea7b16ecdd5665a68669185b4f000c4
https://doi.org/10.1101/644302
https://doi.org/10.1101/644302
Autor:
Vivian W. Tang, Nivetha Kannan
Publikováno v:
Journal of Cell Science.
Actomyosin II contractility in epithelial cell plays an essential role in tension-dependent adhesion strengthening. One key unsettling question is how cellular contraction transmits force to the nascent cell-cell adhesion when there is no stable atta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a764254a9b3d888223dc148da4608c
https://doi.org/10.1242/jcs.211334
https://doi.org/10.1242/jcs.211334