Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vivian W. Lui"'
Autor:
Jennifer R. Grandis, Gordon B. Mills, Julie E. Bauman, Umamaheswar Duvvuri, Vivian W. Lui, Ann M. Egloff, Michele Fichera, Sufi M. Thomas, Zhenlin Ju, Yongseok Park, Sarah Wheeler, Hua Li
Primary HNSCC and PDX jitter plots for data range visualization. 173 primary HNSCC and 12 PDXs are plotted in separate columns by protein. B) 64 proteins expressed at significantly different levels in both primary HNSCC and PDX.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afb80a37034bc6180c2908b47713b8a
https://doi.org/10.1158/1541-7786.22511281.v1
https://doi.org/10.1158/1541-7786.22511281.v1
Autor:
Jennifer R. Grandis, Gordon B. Mills, Julie E. Bauman, Umamaheswar Duvvuri, Vivian W. Lui, Ann M. Egloff, Michele Fichera, Sufi M. Thomas, Zhenlin Ju, Yongseok Park, Sarah Wheeler, Hua Li
HNSCC Protein expression is not associated with patient age or tumor site. 55 deidentified primary HNSCC with TCPA data were analyzed by unsupervised clustering. A) Age categories (by years of age) are represented above the heatmap for each tumor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e2489e0c8ff2fb00f193f2e63edb8e
https://doi.org/10.1158/1541-7786.22511287
https://doi.org/10.1158/1541-7786.22511287
Autor:
Jennifer R. Grandis, Gordon B. Mills, Julie E. Bauman, Umamaheswar Duvvuri, Vivian W. Lui, Ann M. Egloff, Michele Fichera, Sufi M. Thomas, Zhenlin Ju, Yongseok Park, Sarah Wheeler, Hua Li
Proteins expressed differentially in both primary HNSCC and PDXs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138082d44bc6e7356233d0473e072c3b
https://doi.org/10.1158/1541-7786.22511272.v1
https://doi.org/10.1158/1541-7786.22511272.v1
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 109K, TMEM16A expression can be rescued by expression of cDNA that is resistant to the effects of anti-TMEM16A shRNA. Quantitative RT-PCR was used to demonstrate that the knock-down of endogenous TMEM16A induced by shRNA can be rescued by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770336805eb75d4ee51e9768977d0152
https://doi.org/10.1158/0008-5472.22391844.v1
https://doi.org/10.1158/0008-5472.22391844.v1
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 72K, Patient survival is not impacted by TMEM16A amplification status. Disease-specific and overall survival of the cohort of SCCHN patients was not significantly correlated with TMEM16A amplification (A, B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060181eba672a10e59677fb156729b67
https://doi.org/10.1158/0008-5472.22391859
https://doi.org/10.1158/0008-5472.22391859
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 407K, TMEM16A overexpression promotes cell proliferation in HEK-293T cells. TMEM16A overexpression induced cellular proliferation (*P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810245f0d938b4427a3f81c7cd3f2cdc
https://doi.org/10.1158/0008-5472.22391853.v1
https://doi.org/10.1158/0008-5472.22391853.v1
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 109K, TMEM16A inhibition with T16A-inh01 (A01) alone or in combination with the MEK/ERK inhibitor UO126 leads to decreased tumor cell viability in vitro. UM-SCC1 and T24 cells were treated with increasing concentrations of A01. A dose depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d99cbab64d31993cac10bc4f1cb323c
https://doi.org/10.1158/0008-5472.22391841
https://doi.org/10.1158/0008-5472.22391841
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 101K, Cyclin D1 expression is reduced in the proliferating tissues derived from Tmem16a -/- mice when compared to wild-type littermates. Tissues harvested from Tmem16a -/- and wild-type mice were subjected to immunohistochemical staining f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884efc4f04c76bb473171c3180188069
https://doi.org/10.1158/0008-5472.22391847
https://doi.org/10.1158/0008-5472.22391847
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 97K, TMEM16A manipulation via shRNA mediated knock-down or overexpression leads to a measurable change in chloride conductance. Quantitative PCR demonstrates a significant decrease (~75%) in TMEM16A levels after shRNA treatment (A; mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ba3890dabe7f4ae08b91846ca088c2
https://doi.org/10.1158/0008-5472.22391856.v1
https://doi.org/10.1158/0008-5472.22391856.v1
Autor:
Susanne M. Gollin, Jennifer R. Grandis, Vivian W. Lui, Xing Chen, Ann Marie Egloff, Raja S. Seethala, Rainer Schreiber, Karl Kunzelmann, Brian J. Henson, Brian D. Harfe, Jason R. Rock, Robert S. Edinger, Xin Huang, Carol Bertrand, Dong Xiao, Daniel J. Shiwarski, Umamaheswar Duvvuri
PDF file - 139K, Anti-TMEM16A antibody recognizes endogeneous TMEM16A in immunohistochemistry. A rabbit polyclonal antibody was raised against a human TMEM16A epitope (as described in the Materials and Methods). This antibody was validated in immunoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c216334b59bd33a406bf4c40c5797f1
https://doi.org/10.1158/0008-5472.22391862
https://doi.org/10.1158/0008-5472.22391862