Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vivian Prindle"'
Autor:
Yue Fu, David Estoppey, Silvio Roggo, Dominik Pistorius, Florian Fuchs, Christian Studer, Ashraf S. Ibrahim, Thomas Aust, Frederic Grandjean, Manuel Mihalic, Klaus Memmert, Vivian Prindle, Etienne Richard, Ralph Riedl, Sven Schuierer, Eric Weber, Jürg Hunziker, Frank Petersen, Jianshi Tao, Dominic Hoepfner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Biosynthesis of glycosylphosphatidylinositol (GPI) is essential for the integrity of the fungal cell wall. Here, the authors show that the natural product jawsamycin inhibits GPI biosynthesis by targeting a subunit of the fungal UDP-glycosyltransfera
Externí odkaz:
https://doaj.org/article/f7cd22501a204070a70510bf4ba6dfe2
Autor:
Yue Fu, David Estoppey, Silvio Roggo, Dominik Pistorius, Florian Fuchs, Christian Studer, Ashraf S. Ibrahim, Thomas Aust, Frederic Grandjean, Manuel Mihalic, Klaus Memmert, Vivian Prindle, Etienne Richard, Ralph Riedl, Sven Schuierer, Eric Weber, Jürg Hunziker, Frank Petersen, Jianshi Tao, Dominic Hoepfner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d2b7f75c0b374df0a687c5171d690a4d
Autor:
Eric Weber, Juerg Hunziker, Dominic Hoepfner, Ralph Riedl, Vivian Prindle, Sven Schuierer, Yue Fu, Silvio Roggo, Florian Fuchs, Ashraf S. Ibrahim, Jianshi Tao, Frank Petersen, Manuel Mihalic, David Estoppey, Dominik Pistorius, Christian Studer, Etienne Richard, Klaus Memmert, Thomas Aust, Frederic Grandjean
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature communications, vol 11, iss 1
Nature communications, vol 11, iss 1
Biosynthesis of glycosylphosphatidylinositol (GPI) is required for anchoring proteins to the plasma membrane, and is essential for the integrity of the fungal cell wall. Here, we use a reporter gene-based screen in Saccharomyces cerevisiae for the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390861add4674d3014656f11c8eddcee
https://doaj.org/article/f7cd22501a204070a70510bf4ba6dfe2
https://doaj.org/article/f7cd22501a204070a70510bf4ba6dfe2
Autor:
Jianshi Tao, Frank Petersen, Eric Weber, David Estoppey, Vivian Prindle, Sven Schuierer, Christian Studer, Dominik Pistorius, Jürg Hunziker, Etienne Richard, Manuel Mihalic, Klaus Memmert, Ralph Riedl, Silvio Roggo, Ashraf S. Ibrahim, Dominic Hoepfner, Yue Fu, Florian Fuchs, Thomas Aust, Frederic Grandjean
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Nature Communications
Biosynthesis of glycosylphosphatidylinositol (GPI) is required for anchoring proteins to the plasma membrane, and is essential for the integrity of the fungal cell wall. Here, we use a reporter gene-based screen in Saccharomyces cerevisiae for the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044c1d078bd50f0a4ee8f0a580be2d6d
https://doaj.org/article/d2b7f75c0b374df0a687c5171d690a4d
https://doaj.org/article/d2b7f75c0b374df0a687c5171d690a4d
Autor:
Vladimir E. Diaz-Ochoa, Grace John-Stewart, Vivian Prindle, Judd L. Walson, Helen L. Gerns Storey, Jackie Naulikha, David Camerini, Phil Felgner, Helen Horton, Barbra A. Richardson, Benson Singa
Publikováno v:
AIDS Research and Human Retroviruses. 30:37-44
The role of HIV-1-specific antibody responses in HIV disease progression is complex and would benefit from analysis techniques that examine clusterings of responses. Protein microarray platforms facilitate the simultaneous evaluation of numerous prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0b9b0e2ceaf108de9e1e02d4661234
https://doi.org/10.1089/aid.2013.0088
https://doi.org/10.1089/aid.2013.0088
Autor:
Sven Schuierer, Lukas Oberer, Ralph Riedl, Jianshi Tao, Silvio Roggo, John S. Gounarides, Charlotte Miault, Stephen B. Helliwell, Marc Bergdoll, Juan Zhang, Klaus Memmert, Anais Margerit, Dominic Hoepfner, Pierre-Eloi Imbert, Christian N. Parker, Shantanu Karkare, Andreas Hofmann, Stefan Reinker, Hans-Ulrich Naegeli, Mathias Frederiksen, Alban Muller, Hong Yin, Ireos Filipuzzi, Trixie Wagner, Juliet R. Leighton-Davis, Alain Rahier, Philipp Krastel, Vivian Prindle, Celine Fioretto, Richard Knochenmuss, Thomas Aust, N. Rao Movva, Jessica A. Sexton, Rolf Jeker
Publikováno v:
Nature Communications
FR171456 is a natural product with cholesterol-lowering properties in animal models, but its molecular target is unknown, which hinders further drug development. Here we show that FR171456 specifically targets the sterol-4-alpha-carboxylate-3-dehydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833373929a95fd5be399ab110427a767
https://doi.org/10.1038/ncomms9613
https://doi.org/10.1038/ncomms9613
Autor:
Meir Glick, Melissa L Grippo, Jianshi Tao, Amanda Cobos-Correa, John W. Davies, Eugen Lounkine, Philipp Krastel, Christian Studer, Gaelle C. Le Goff, Vivian Prindle, Frederick J. King, Christian N. Parker, Dominic Hoepfner, Shanni Chen, Ansgar Schuffenhauer, Anne Mai Wassermann, Iain M. Wallace, John M Peltier
Publikováno v:
Nature chemical biology. 11(12)
High-throughput screening (HTS) is an integral part of early drug discovery. Herein, we focused on those small molecules in a screening collection that have never shown biological activity despite having been exhaustively tested in HTS assays. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c125c7332c5b0ed126d2d0f2a6f73e4
https://pubmed.ncbi.nlm.nih.gov/26585537
https://pubmed.ncbi.nlm.nih.gov/26585537
Autor:
Dominic Hoepfner, Simona Cotesta, Sven Schuierer, Neil S. Ryder, John A. Tallarico, Jianshi Tao, David Estoppey, Daryl L. Richie, Ralph Riedl, Katherine V. Thompson, Christian Studer, Jessica A. Sexton, Thomas Zabawa, Vivian Prindle, Thomas Aust, Joseph Drumm, Nicole Hartmann, Jürg Eichenberger, N. Rao Movva
Publikováno v:
Antimicrobial agents and chemotherapy. 57(5)
High-throughput phenotypic screening against the yeast Saccharomyces cerevisiae revealed a series of triazolopyrimidine-sulfonamide compounds with broad-spectrum antifungal activity, no significant cytotoxicity, and low protein binding. To elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd533e8cb815bcb4a30057233aec0744
https://pubmed.ncbi.nlm.nih.gov/23478965
https://pubmed.ncbi.nlm.nih.gov/23478965