Výsledky vyhledávání - "Vivian P. Thompson"

Akademický článek

Antimicrobials cetylpyridinium-chloride and miramistin demonstrate non-inferiority and no 'protein-error' compared to established wound care antiseptics in vitro

Autor: Julian-Dario Rembe, Vivian-Denise Thompson, Ewa Klara Stuermer

Publikováno v: AIMS Microbiology, Vol 8, Iss 4, Pp 372-387 (2022)

Concern about microbial tolerance and resistance to established antimicrobials drives research into alternatives for local antiseptic wound treatment. Precise efficacy profiles are thereby important in the evaluation of potential alternative antimicr

Externí odkaz: https://doaj.org/article/8052c1e335f54d72b31a1af9e9668e50

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Changes in Serum Calcitonin Concentrations, Incidence of Medullary Thyroid Carcinoma, and Impact of Routine Calcitonin Concentration Monitoring in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL)

Autor: Peter Öhman, Robert F. Gagel, Peter Merrill, John B. Buse, Adrian F. Hernandez, Vivian P. Thompson, Shelby D. Reed, Rishi A Patel, Yanhong Li, Stephanie M. Gustavson, Brian G. Katona, Rury R. Holman, Nayyar Iqbal, M. Angelyn Bethel, Sara Ahmadi

Publikováno v: Diabetes Care

OBJECTIVE Increases in serum calcitonin, a tumor marker for medullary thyroid carcinoma (MTC), have been associated with glucagon-like peptide 1 receptor agonist use in some preclinical studies. We report calcitonin changes in exenatide-treated and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879f43610428489aa17714a4f963a0be
https://doi.org/10.2337/dc18-2028

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Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)

Autor: M. Angelyn Bethel, Adrian F. Hernandez, Ambady Ramachandran, Peter Öhman, John B. Buse, Stephanie M. Gustavson, Robert J. Mentz, Nayyar Iqbal, Juliana C.N. Chan, Aldo P. Maggioni, Neil Poulter, Bernard Zinman, Vivian P. Thompson, Rury R. Holman, Steven P. Marso, Neha J. Pagidipati

Publikováno v: Am Heart J

Background EXSCEL is a randomized, double-blind, placebo-controlled trial examining the effect of exenatide once-weekly (EQW) versus placebo on time to the primary composite outcome (cardiovascular death, nonfatal myocardial infarction or nonfatal st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db39c5b0d7a27ad6cd7775e76109a89
https://doi.org/10.1016/j.ahj.2017.02.005

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Effects of Once-Weekly Exenatide on Clinical Outcomes in Patients With Preexisting Cardiovascular Disease

Autor: Robert J, Mentz, Vivian P, Thompson, David, Aguilar, Jasmine, Choi, Stephanie M, Gustavson, Nayyar, Iqbal, Alice P, Kong, Peter, Öhman, Naveed, Sattar, Russell S, Scott, Yee Weng, Wong, Rury R, Holman, Adrian F, Hernandez

Publikováno v: Circulation. 138(22)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::492ceab0b0ddc3f4453b6aaa94ffb183
https://pubmed.ncbi.nlm.nih.gov/30571356

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5257Effects of once-weekly exenatide on clinical outcomes in the subgroup of patients with pre-existing cardiovascular disease: insights from EXSCEL

Autor: Peter Öhman, Vivian P. Thompson, Stephanie M. Gustavson, Nayyar Iqbal, Rury R. Holman, Robert J. Mentz, Adrian F. Hernandez

Publikováno v: European Heart Journal. 39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec382b5d86e5d8c7f0f5e194a3e026f1
https://doi.org/10.1093/eurheartj/ehy566.5257

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Soluble ST2 in Ambulatory Patients With Heart Failure

Autor: William E. Kraus, Kirkwood F. Adams, Vivian P. Thompson, Dalane W. Kitzman, Mark P. Donahue, Linda K. Shaw, Megan L. Neely, Tariq Ahmad, Faiez Zannad, Ileana L. Piña, G. Michael Felker, Christopher M. O'Connor, Mona Fiuzat, David J. Whellan

Publikováno v: Circulation: Heart Failure. 6:1172-1179

Background— ST2 is involved in cardioprotective signaling in the myocardium and has been identified as a potentially promising biomarker in heart failure (HF). We evaluated ST2 levels and their association with functional capacity and long-term cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf49221723dcf562394463d16569aeb
https://doi.org/10.1161/circheartfailure.113.000207

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A Randomized, Double-Blind, Active-Controlled Phase 2 Trial to Evaluate a Novel Selective and Reversible Intravenous and Oral P2Y 12 Inhibitor Elinogrel Versus Clopidogrel in Patients Undergoing Nonurgent Percutaneous Coronary Intervention

Autor: Gayle Paynter, Daniel D. Gretler, Mina Madan, Robert A. Harrington, Lisa G. Berdan, Matthew W. McClure, Dominick J. Angiolillo, Sunil V. Rao, Janusz Kochman, C. Michael Gibson, William J. French, Paul A. Gurbel, Robert C. Welsh, Uwe Zeymer, Sergio Leonardi, Kurt Huber, Vivian P. Thompson, Deepak L. Bhatt

Publikováno v: Circulation: Cardiovascular Interventions. 5:336-346

Background— We evaluated the safety, efficacy, and tolerability of elinogrel, a competitive, reversible intravenous and oral P2Y 12 inhibitor that does not require metabolic activation, in patients undergoing nonurgent percutaneous coronary interve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a632a41cf6f78b4f885cb7f3783dff3
https://doi.org/10.1161/circinterventions.111.964197

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Regulated Expression of ADAMTS Family Members in Follicles and Cumulus Oocyte Complexes: Evidence for Specific and Redundant Patterns During Ovulation1

Autor: JoAnne S. Richards, Yuet Lo, Allison E. Falender, John D. Sandy, Immaculada Hernandez-Gonzalez, Derek Boerboom, Kari M. H. Doyle, Richard G. LeBaron, Vivian P. Thompson, Ignacio Gonzalez-Robayna, Eva Teuling

Publikováno v: Biology of Reproduction. 72:1241-1255

Protease cascades are essential for many biological events, including the LH-induced process of ovulation. ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin-like repeats-1) is expressed and hormonally regulated in the ovary by LH and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac0920c7b28cd2b71d7659aa557c094b
https://doi.org/10.1095/biolreprod.104.038083

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Activation of the Proteolytic Activity of ADAMTS4 (Aggrecanase-1) by C-terminal Truncation

Autor: John D. Sandy, Paul E. Gottschall, Vivian P. Thompson, Jennifer Westling, Troy D. Howell, Gui Gao

Publikováno v: Journal of Biological Chemistry. 277:11034-11041

Proteolysis of the hyalectans (aggrecan, versican, brevican) in vivo appears to result from the activity of ADAMTS4 (aggrecanase-1, herein referred to as an hyalectanase). To examine the mode of activation of ADAMTS4, a human chondrosarcoma cell line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4dbddc9bee17c4327b7e57dfa5f830
https://doi.org/10.1074/jbc.m107443200

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The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1

Autor: Kurt Doege, John D. Sandy, Christie Verscharen, Vivian P. Thompson

Publikováno v: Biochemical Journal. 351:161-166

We have examined the abundance and structure of intermediates in the chondrocyte-mediated degradation of aggrecan by aggrecanase(s). Degradation products were identified by Western-blot analysis with antibodies to cleavage-site neoepitopes and to pep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17a3d89f31f48b0241d54e6e96f0bf69
https://doi.org/10.1042/bj3510161

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