Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vivian Koch"'
Publikováno v:
Molecular Therapy: Oncolytics, Vol 15, Iss , Pp 186-200 (2019)
Measles virus (MeV) is naturally cytolytic by extensive cell-to-cell fusion. Vaccine-derived MeV is toxic for cancer cells and is clinically tested as oncolytic virus. To combine the potential of MeV with enhanced safety, different targeting strategi
Externí odkaz:
https://doaj.org/article/8c68c3450c474b758f4a914f0657803a
Autor:
Jan RH Hanauer, Lisa Gottschlich, Dennis Riehl, Tillmann Rusch, Vivian Koch, Katrin Friedrich, Stefan Hutzler, Steffen Prüfer, Thorsten Friedel, Kay-Martin Hanschmann, Robert C Münch, Christian Jost, Andreas Plückthun, Klaus Cichutek, Christian J Buchholz, Michael D Mühlebach
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
To target oncolytic measles viruses (MV) to tumors, we exploit the binding specificity of designed ankyrin repeat proteins (DARPins). These DARPin-MVs have high tumor selectivity while maintaining excellent oncolytic potency. Stability, small size, a
Externí odkaz:
https://doaj.org/article/10476f0ec29d4a0b936f939cc2196b72
Autor:
Robert C. Münch, Tillmann Rusch, Klaus Cichutek, Thorsten Friedel, Stefan Hutzler, Lisa Gottschlich, Katrin Friedrich, Jan R.H. Hanauer, Steffen Prüfer, Christian J. Buchholz, Christian Jost, Vivian Koch, Dennis Riehl, Michael D. Mühlebach, Kay-Martin Hanschmann, Andreas Plückthun
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
To target oncolytic measles viruses (MV) to tumors, we exploit the binding specificity of designed ankyrin repeat proteins (DARPins). These DARPin-MVs have high tumor selectivity while maintaining excellent oncolytic potency. Stability, small size, a
Autor:
Vivian Koch, Anke Muth, Stefan Hutzler, Vivian A. Scheuplein, Stefan Schülke, Christian J. Buchholz, Zoe Waibler, Katharina M. Uhlig, Bianca S. Bodmer, Stefanie Kugelmann, Johannes Reusch, Michael D. Mühlebach, Axel Schambach, Anna H. Malczyk, Stephan Scheurer
Publikováno v:
Journal of virology. 89(17)
To induce and trigger innate and adaptive immune responses, antigen-presenting cells (APCs) take up and process antigens. Retroviral particles are capable of transferring not only genetic information but also foreign cargo proteins when they are gene