Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vivian K. Diep"'
Autor:
Gloria Yiu, Tue Kruse Rasmussen, Brandon L. Tsai, Vivian K. Diep, David J. Haddon, Jennifer Tsoi, Gopika D. Miller, Begoña Comin-Anduix, Bent Deleuran, Gay M. Crooks, Paul J. Utz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The establishment of an “interferon (IFN) signature” to subset SLE patients on disease severity has led to therapeutics targeting IFNα. Here, we investigate IFN signaling in SLE using multiplexed protein arrays and single cell cytometry by time
Externí odkaz:
https://doaj.org/article/9c4d59dbaa9c4bd5907b224d9ec6e824
Autor:
Vivian K. Diep, Winston A. Haynes, Paul J. Utz, Rong Mao, Avani Khatri, Christopher R. Bolen, Gloria Yiu, Erika Bongen, Imelda Balboni, Purvesh Khatri, D. James Haddon
Publikováno v:
JCI Insight. 5
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that follows an unpredictable disease course and affects multiple organs and tissues. We performed an integrated, multicohort analysis of 7,471 transcriptomic profiles from 40 indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38238a8f9ebebecbc676a292f8fd2c0
https://doi.org/10.1172/jci.insight.122312
https://doi.org/10.1172/jci.insight.122312
Autor:
Paul J. Utz, Erika Bongen, Vivian K. Diep, D. James Haddon, Rong Mao, Avani Khatri, Imelda Balboni, Gloria Yiu, Winston A. Haynes, Christopher R. Bolen, Purvesh Khatri
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that follows an unpredictable disease course and affects multiple organs and tissues. We performed an integrated, multi-cohort analysis of 7,471 transcriptomic profiles from 40 indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32d3ae81ac5b2776633532420623070
Autor:
Grace M. Credo, Drew A. Hall, Jordan V. Price, Michelle Petri, Shan X. Wang, Paul J. Utz, D. James Haddon, Nidhi Gupta, Vivian K. Diep, Madoo Varma, Emily C. Baechler, Jung Rok Lee, Kyunglok Kim
Publikováno v:
ACS Nano. 10:10652-10660
Autoantibodies are a hallmark of autoimmune diseases such as lupus and have the potential to be used as biomarkers for diverse diseases, including immunodeficiency, infectious disease, and cancer. More precise detection of antibodies to specific targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4496e5be1e7cbdad57014a3166103087
https://doi.org/10.1021/acsnano.6b03786
https://doi.org/10.1021/acsnano.6b03786
Autor:
Vivian K. Diep, D. James Haddon, Jordan V. Price, Drew A. Hall, Emily C. Baechler, Paul J. Utz, Imelda Balboni, Shan X. Wang, Hannah Wand, Jung Rok Lee, Michelle Petri
Publikováno v:
Scientific reports, vol 6, iss 1
Scientific Reports
Scientific Reports
High titer, class-switched autoantibodies are a hallmark of systemic lupus erythematosus (SLE). Dysregulation of the interferon (IFN) pathway is observed in individuals with active SLE, although the association of specific autoantibodies with chemoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084d9d76d9935ed67ab93e6a531c7e4d
Autor:
Vivian K. Diep, Gloria Yiu, David James Haddon, Paul J. Utz, James D. Faix, Lawrence Steinman, Stephanie Tangsombatvisit, Winston A. Haynes, Alvina D. Chu, Bahareh Ajami, Tue Kruse Rasmussen
Publikováno v:
Arthritis & Rheumatology.
Objective Type I interferon (IFN) signaling is a central pathogenic pathway in systemic lupus erythematosus (SLE), and therapeutics targeting type I IFN signaling are in development. Multiple proteins with overlapping functions play a role in IFN sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cadda23eb0ea174e81bfb2c986cbafbf
https://doi.org/10.1002/art.39535
https://doi.org/10.1002/art.39535
Autor:
Justin A. Jarrell, Vivian K. Diep, Sally Mackey, Chih Long Liu, Jordan V. Price, Emily C. Baechler, Stephanie Tangsombatvisit, Paul J. Utz, Hannah Wand, Madoo Varma, David James Haddon, Grace M. Credo, Cornelia L. Dekker
The mechanisms underlying development of ribonucleoprotein (RNP) autoantibodies are unclear. The U1-70K protein is the predominant target of RNP autoantibodies, and the RNA binding domain has been shown to be the immunodominant autoantigenic region o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86cb861cb0d3f3565feaf526a17c3b8
https://europepmc.org/articles/PMC4815922/
https://europepmc.org/articles/PMC4815922/
Publikováno v:
Arthritis Research & Therapy
Introduction Pediatric systemic lupus erythematosus (pSLE) patients often initially present with more active and severe disease than adults, including a higher frequency of lupus nephritis. Specific autoantibodies, including anti-C1q, anti-DNA and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fdbefaf426c6cd722b6793ab1d0524