Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Vivian H Gersuk"'
Autor:
Hannah A DeBerg, Mussaret B Zaidi, Matthew C Altman, Prasong Khaenam, Vivian H Gersuk, Freddy D Campos, Iza Perez-Martinez, Mario Meza-Segura, Damien Chaussabel, Jacques Banchereau, Teresa Estrada-Garcia, Peter S Linsley
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0192082 (2018)
Globally, diarrheal diseases are a leading cause of death in children under five and disproportionately affect children in developing countries. Children who contract diarrheal diseases are rarely screened to identify the etiologic agent due to time
Externí odkaz:
https://doaj.org/article/ec9483f875f64f2ea994a2f03298c003
Autor:
Erin M. Witkop, Kirsten Diggins, Alice Wiedeman, Elisavet Serti, Gerald Nepom, Vivian H. Gersuk, Bryce Fuchs, S. Alice Long, Peter S. Linsley
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Distinct Natural Killer (NK)-like CD57+ and PD-1+ CD8+ exhausted-like T cell populations (Tex) have both been linked to beneficial immunotherapy response in autoimmune type 1 diabetes (T1D) patients. The origins and relationships between the
Externí odkaz:
https://doaj.org/article/8d3fb1a37da44494b3b4cd1c67e7d55e
Autor:
Eddie A James, Theresa J Gates, Rebecca E LaFond, Shinobu Yamamoto, Chester Ni, Duy Mai, Vivian H Gersuk, Kimberly O'Brien, Quynh-Anh Nguyen, Brad Zeitner, Marion C Lanteri, Philip J Norris, Damien Chaussabel, Uma Malhotra, William W Kwok
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005375 (2016)
Most West Nile virus (WNV) infections are asymptomatic, but some lead to neuroinvasive disease with symptoms ranging from disorientation to paralysis and death. Evidence from animal models suggests that neuroinvasive infections may arise as a consequ
Externí odkaz:
https://doaj.org/article/f6ca62c9052a4030852fe4ae4899c377
Autor:
Ivana Durinovic-Belló, Vivian H Gersuk, Chester Ni, Rebecca Wu, Jerill Thorpe, Nicholas Jospe, Srinath Sanda, Carla J Greenbaum, Gerald T Nepom
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98074 (2014)
Fate determination for autoreactive T cells relies on a series of avidity-dependent interactions during T cell selection, represented by two general types of signals, one based on antigen expression and density during T cell development, and one base
Externí odkaz:
https://doaj.org/article/5c1f3d12ff434afd83a179e2502e4265
Autor:
Paul L Bollyky, Jeffrey B Bice, Ian R Sweet, Ben A Falk, John A Gebe, April E Clark, Vivian H Gersuk, Alan Aderem, Thomas R Hawn, Gerald T Nepom
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5063 (2009)
Commensal flora and pathogenic microbes influence the incidence of diabetes in animal models yet little is known about the mechanistic basis of these interactions. We hypothesized that Myd88, an adaptor molecule in the Toll-like-receptor (TLR) pathwa
Externí odkaz:
https://doaj.org/article/9987147706c64cf880f4caff02e0835c
Autor:
Megan E. Smithmyer, Alice E. Wiedeman, David A. G. Skibinski, Adam K. Savage, Carolina Acosta‐Vega, Sheila Scheiding, Vivian H. Gersuk, Colin O'Rourke, S. Alice Long, Jane H. Buckner, Cate Speake
Publikováno v:
Cytometry Part A. 101:351-360
Mislabeling samples or data with the wrong participant information can affect study integrity and lead investigators to draw inaccurate conclusions. Quality control to prevent these types of errors is commonly embedded into the analysis of genomic da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f7514fbf3c8220c91d9b6a7f55b1b0
https://doi.org/10.1002/cyto.a.24525
https://doi.org/10.1002/cyto.a.24525
Autor:
Matthew M. Yeh, Bruk Molla, Julia Yue Cui, Yen-Ying Chen, Gabby Mascarinas, Peter S. Linsley, Vivian H. Gersuk, Christopher E. Savard, Yi-Jen Peng, George N. Ioannou, Sum P. Lee, Moumita Dutta
Publikováno v:
Hepatology Communications. 6:780-794
Proprotein convertase subtilisin/kexin type 9 (Pcsk9) binds to hepatic low-density lipoprotein receptor (LDLR) and induces its internalization and degradation. Pcsk9 inhibition increases LDLR expression by hepatocytes, which causes increased uptake o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82125ddcac6aee1a793bee4fce75805
https://doi.org/10.1002/hep4.1858
https://doi.org/10.1002/hep4.1858
Autor:
Hamid Bolouri, Rhonda E. Ries, Alice E. Wiedeman, Tiffany Hylkema, Sheila Scheiding, Vivian H. Gersuk, Kimberly O’Brien, Quynh-Anh Nguyen, Jenny L. Smith, S. Alice Long, Soheil Meshinchi
Publikováno v:
Nature communications. 13(1)
High levels of the inflammatory cytokine IL-6 in the bone marrow are associated with poor outcomes in pediatric acute myeloid leukemia (pAML), but its etiology remains unknown. Using RNA-seq data from pre-treatment bone marrows of 1489 children with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358fe516b34aeeec2d79ca89662ab3ab
https://pubmed.ncbi.nlm.nih.gov/36418348
https://pubmed.ncbi.nlm.nih.gov/36418348
Autor:
Veronique Bajzik, Hannah A. DeBerg, Nahir Garabatos, Blake J. Rust, Kimberly K. Obrien, Quynh‐Anh Nguyen, Colin O’Rourke, Alex Smith, Alex H. Walker, Charlie Quinn, Vivian H. Gersuk, Mary Farrington, David Jeong, Brian P. Vickery, Daniel C. Adelman, Erik Wambre
Publikováno v:
Allergy. 77(8)
The PALISADE study, an international, phase 3 trial of peanut oral immunotherapy (POIT) with AR101, resulted in desensitization in children and adolescents who were highly allergic to peanut. An improved understanding of the immune mechanism induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a7e2e9605dc19a963caaadaf438831
https://pubmed.ncbi.nlm.nih.gov/35266148
https://pubmed.ncbi.nlm.nih.gov/35266148
Autor:
Katharina Lambert, Keagan G. Moo, Azlann Arnett, Gautam Goel, Alex Hu, Kaitlin J. Flynn, Cate Speake, Alice E. Wiedeman, Vivian H. Gersuk, Peter S. Linsley, Carla J. Greenbaum, S. Alice Long, Rebecca Partridge, Jane H. Buckner, Bernard Khor
Publikováno v:
Sci Transl Med
Individuals with Down syndrome show cellular and clinical features of dysregulated aging of the immune system, including a shift from naïve to memory T cells and increased incidence of autoimmunity. However, a quantitative understanding of how vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e77669817b9a186f6f588776631627
https://europepmc.org/articles/PMC9312285/
https://europepmc.org/articles/PMC9312285/
