Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Vivian G Cheung"'
Autor:
Bolajoko O Olusanya, Mijna Hadders-Algra, Nem Yun Boo, Ricardo Halpern, Vivian G Cheung, M K C Nair
Publikováno v:
BMJ Paediatrics Open, Vol 6, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/27263c07f0ba469ea8cdbdf49cafa163
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 7, Pp 1-14 (2015)
Abstract Individual differences in sensitivity to insulin contribute to disease susceptibility including diabetes and metabolic syndrome. Cellular responses to insulin are well studied. However, which steps in these response pathways differ across in
Externí odkaz:
https://doaj.org/article/a3996a1cb1d04acc9db3afae30af4688
Autor:
Vivian G Cheung, Renuka R Nayak, Isabel Xiaorong Wang, Susannah Elwyn, Sarah M Cousins, Michael Morley, Richard S Spielman
Publikováno v:
PLoS Biology, Vol 8, Iss 9 (2010)
Expression levels of human genes vary extensively among individuals. This variation facilitates analyses of expression levels as quantitative phenotypes in genetic studies where the entire genome can be scanned for regulators without prior knowledge
Externí odkaz:
https://doaj.org/article/135c66c9ef5b43789c61e7e865406373
Publikováno v:
PLoS Genetics, Vol 5, Iss 9, p e1000648 (2009)
The number of recombination events per meiosis varies extensively among individuals. This recombination phenotype differs between female and male, and also among individuals of each gender. In this study, we used high-density SNP genotypes of over 2,
Externí odkaz:
https://doaj.org/article/3d41d96f680e47f4af4ec6de1c084ffc
Autor:
Alkes L Price, Nick Patterson, Dustin C Hancks, Simon Myers, David Reich, Vivian G Cheung, Richard S Spielman
Publikováno v:
PLoS Genetics, Vol 4, Iss 12, p e1000294 (2008)
Variation in gene expression is a fundamental aspect of human phenotypic variation. Several recent studies have analyzed gene expression levels in populations of different continental ancestry and reported population differences at a large number of
Externí odkaz:
https://doaj.org/article/1b3ca09f24b84d74829a90298f42bb9c
Autor:
Jason A Watts, Christopher Grunseich, Yesenia Rodriguez, Yaojuan Liu, Dongjun Li, Joshua T Burdick, Alan Bruzel, Robert J Crouch, Robert W Mahley, Samuel H Wilson, Vivian G Cheung
Publikováno v:
Nucleic Acids Res
RNA is modified by hundreds of chemical reactions and folds into innumerable shapes. However, the regulatory role of RNA sequence and structure and how dysregulation leads to diseases remain largely unknown. Here, we uncovered a mechanism where RNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34db6494b76e0b415e1f824b580bf63
https://doi.org/10.1093/nar/gkac1107
https://doi.org/10.1093/nar/gkac1107
Autor:
Vivian G. Cheung, Kuang-Yu Jen
The tumor suppressor p53 plays an essential role in cellular adaptation to stress. In response to ionizing radiation, p53 regulates the transcription of genes in a diverse set of pathways including DNA repair, cell cycle arrest, and apoptosis. Previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d705122ed9f75f2608b046af7b0fd7
https://doi.org/10.1158/0008-5472.c.6494420.v1
https://doi.org/10.1158/0008-5472.c.6494420.v1
Autor:
Vivian G. Cheung, Kuang-Yu Jen
Also includes supplementary methods and materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d1e03227892627af46d5ec5c7e5357
https://doi.org/10.1158/0008-5472.22364888
https://doi.org/10.1158/0008-5472.22364888
Autor:
Vivian G. Cheung, Richard J. Maraia, Peter H. Byers, Jessica A. Brown, Juan D. Alfonzo, Robert L. Ross
Publikováno v:
Nature Genetics. 53:1113-1116
For most organisms, DNA sequences are available, but the complete RNA sequences are not. Here, we call for technologies to sequence full-length RNAs with all their modifications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd8dfd281f459bf46ec719a52624342
https://doi.org/10.1038/s41588-021-00903-1
https://doi.org/10.1038/s41588-021-00903-1
Autor:
Jason A. Watts, Christopher Grunseich, Yesenia Rodriguez, Yaojuan Liu, Dongjun Li, Joshua T Burdick, Alan Bruzel, Robert J. Crouch, Robert W. Mahley, Samuel H. Wilson, Vivian G. Cheung
The DNA genetic code and the RNA regulatory code determine phenotypes from gene expression to disease susceptibility. DNA sequence variants lead to phenotypic differences among individuals, while within an individual, RNA dynamically confers cell ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaad3494e85502d6d93caa34951b8104
https://doi.org/10.1101/2022.05.01.489793
https://doi.org/10.1101/2022.05.01.489793