Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Vivian G, Cheung"'
Autor:
Bolajoko O Olusanya, Mijna Hadders-Algra, Nem Yun Boo, Ricardo Halpern, Vivian G Cheung, M K C Nair
Publikováno v:
BMJ Paediatrics Open, Vol 6, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/27263c07f0ba469ea8cdbdf49cafa163
Publikováno v:
Children, Vol 10, Iss 1, p 155 (2023)
Prior to the launch of the United Nations’ Sustainable Development Goals (SDGs) in 2015, childhood disability was rarely considered an important subject in global health. The SDGs till 2030 now require that children under 5 years who are at risk of
Externí odkaz:
https://doaj.org/article/22adca7578b14ebf8b370ab8df4c60c8
Autor:
Jason A Watts, Christopher Grunseich, Yesenia Rodriguez, Yaojuan Liu, Dongjun Li, Joshua T Burdick, Alan Bruzel, Robert J Crouch, Robert W Mahley, Samuel H Wilson, Vivian G Cheung
Publikováno v:
Nucleic Acids Res
RNA is modified by hundreds of chemical reactions and folds into innumerable shapes. However, the regulatory role of RNA sequence and structure and how dysregulation leads to diseases remain largely unknown. Here, we uncovered a mechanism where RNA a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 3995-4007 (2016)
Meiotic recombination is an essential step in gametogenesis, and is one that also generates genetic diversity. Genome-wide association studies (GWAS) and molecular studies have identified genes that influence of human meiotic recombination. RNF212 is
Externí odkaz:
https://doaj.org/article/eb0b611412e54bff9d91e8eea8dcdea9
Autor:
Vivian G. Cheung, Kuang-Yu Jen
The tumor suppressor p53 plays an essential role in cellular adaptation to stress. In response to ionizing radiation, p53 regulates the transcription of genes in a diverse set of pathways including DNA repair, cell cycle arrest, and apoptosis. Previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d705122ed9f75f2608b046af7b0fd7
https://doi.org/10.1158/0008-5472.c.6494420.v1
https://doi.org/10.1158/0008-5472.c.6494420.v1
Autor:
Vivian G. Cheung, Kuang-Yu Jen
Also includes supplementary methods and materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d1e03227892627af46d5ec5c7e5357
https://doi.org/10.1158/0008-5472.22364888
https://doi.org/10.1158/0008-5472.22364888
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 7, Pp 1-14 (2015)
Abstract Individual differences in sensitivity to insulin contribute to disease susceptibility including diabetes and metabolic syndrome. Cellular responses to insulin are well studied. However, which steps in these response pathways differ across in
Externí odkaz:
https://doaj.org/article/a3996a1cb1d04acc9db3afae30af4688
Autor:
Vivian G. Cheung, Richard J. Maraia, Peter H. Byers, Jessica A. Brown, Juan D. Alfonzo, Robert L. Ross
Publikováno v:
Nature Genetics. 53:1113-1116
For most organisms, DNA sequences are available, but the complete RNA sequences are not. Here, we call for technologies to sequence full-length RNAs with all their modifications.
Autor:
Isabel X. Wang, Leighton J. Core, Hojoong Kwak, Lauren Brady, Alan Bruzel, Lee McDaniel, Allison L. Richards, Ming Wu, Christopher Grunseich, John T. Lis, Vivian G. Cheung
Publikováno v:
Cell Reports, Vol 6, Iss 5, Pp 906-915 (2014)
RNA sequences are expected to be identical to their corresponding DNA sequences. Here, we found all 12 types of RNA-DNA sequence differences (RDDs) in nascent RNA. Our results show that RDDs begin to occur in RNA chains ∼55 nt from the RNA polymera
Externí odkaz:
https://doaj.org/article/5f2aebfb28ce422f95afdc0f229f309e
Autor:
Jason A. Watts, Christopher Grunseich, Yesenia Rodriguez, Yaojuan Liu, Dongjun Li, Joshua T Burdick, Alan Bruzel, Robert J. Crouch, Robert W. Mahley, Samuel H. Wilson, Vivian G. Cheung
The DNA genetic code and the RNA regulatory code determine phenotypes from gene expression to disease susceptibility. DNA sequence variants lead to phenotypic differences among individuals, while within an individual, RNA dynamically confers cell ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaad3494e85502d6d93caa34951b8104
https://doi.org/10.1101/2022.05.01.489793
https://doi.org/10.1101/2022.05.01.489793