Sequencing by Avidity Enables High Accuracy With Low Reagent Consumption

Autor: Sinan Arslan, Matthew Kellinger, Semyon Kruglyak, Jake LeVieux, Adeline Mah, Haosen Wang, Junhua Zhao, Chunhong Zhou, John Bailey, Matthew Byrne, Chiting Chang, Steve Chen, Claudia Dennler, Samantha Dennler, Vivian Dien, Derek Fuller, Francisco Garcia, Minghao Guo, Ryan Kelley, Omid Khandan, Michael Klein, Michael Kim, Bill Lin, Yu Liu, Tyler Lopez, Peter Mains, Andrew Price, Hermes Taylor, Ramreddy Tippana, Austin Tomaney, Richard Zhang, Minna Abtahi, Mark Ambroso, Rosi Bajari, Ava Bellizi, Chris Benitez, Daniel Berard, Lorenzo Berti, Kelly Blease, Angela Blum, Andrew Boddicker, Leo Bondar, Chris Bui, Kevin Cappa, Joshua Chan, Victor Chang, Katia Charov, Xiyi Chen, Rodger Constandse, Weston Damron, Mariam Dawood, Nicole Debruno, John Dmalanta, Laure Edoli, Keerthi Elango, Nikka Faustino, Chao Feng, Matthew Ferrari, Kieth Frankie, Adam Fries, Anne Galloway, Vlad Gavrila, Gregory Gemmen, James Ghadiali, Logan Goddard, Adriana Roginski, Garren Hendricks, Jendrick Hentschel, Doris Hseih, Yu-Hsein Hwang-fu, Scott Im, Chaoyi Jin, Daniel Kincade, Bryan Lajooie, Shawn Levy, Yu Li, Vincent Liang, William Light, Jonathan Lipsher, Tsungli Liu, Guixia Long, Rui Ma, Jack Mailloux, Kyle Mandla, Anyssa Martinez, Max Mass, Michael Meron, Celyne Moh, Rachel Moore, Juan Moreno, Jordan Neysmith, Cassandra Niman, Jesus Nunez, Micah Ojeda, Jenna Owens, Sara Espinosa Ortiz, Geoffrey Piland, Dan Proctor, Josua Purba, Michael Ray, Daisong Rong, Virginia Saade, Sanchari Saha, Luqmanal Sirajudeen, Gudrun Stengel, Ryan Stinson, Michael Stone, Keoni Sundseth, Eileen Thai, Connor Thompson, Gustav Santo Tomas, Christy Trejo, Greg Trieger, Diane Truong, Ben Tse, Benjamin Voiles, Henry Vuong, Jennifer Wong, Chiung-Ting Wu, Hua Yu, Ming Yu, Cindy Zhang, Da Zhao, Frank Zheng, Molly He, Michael Previte

We present a novel sequencing chemistry implemented as part of the AVITI system. Relying on the proximal DNA binding sites created through DNA amplification on a solid support, avidity sequencing uses multivalent nucleotide ligands on dye-labeled cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f97fa97146160e939ade0e785052a2c6
https://doi.org/10.21203/rs.3.rs-1965701/v1