Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Vivian B, Dissette"'
Autor:
Alistair J. Cochran, Jesus Gomez-Navarro, John A. Glaspy, Itsushi Peter Shintaku, Vivian B. Dissette, Jason Jalil, Lilah F. Morris, Pilar de la Rocha, Timothy R. Donahue, James S. Economou, Begoña Comin-Anduix, Antoni Ribas
Purpose: CTL-associated antigen 4 (CTLA4)-blocking monoclonal antibodies induce long-term regression of metastatic melanoma in some patients, but the exact mechanism is unknown. In this study, biopsies of selected accessible tumor lesions from patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e7d895d6b297e5b8054d157527d94a
https://doi.org/10.1158/1078-0432.c.6516898.v1
https://doi.org/10.1158/1078-0432.c.6516898.v1
Autor:
Alistair J. Cochran, Jesus Gomez-Navarro, John A. Glaspy, Itsushi Peter Shintaku, Vivian B. Dissette, Jason Jalil, Lilah F. Morris, Pilar de la Rocha, Timothy R. Donahue, James S. Economou, Begoña Comin-Anduix, Antoni Ribas
Supplementary Figures S1-S2 from Intratumoral Immune Cell Infiltrates, FoxP3, and Indoleamine 2,3-Dioxygenase in Patients with Melanoma Undergoing CTLA4 Blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339ce47d5b582f32b1f6f69a2204138e
https://doi.org/10.1158/1078-0432.22439428
https://doi.org/10.1158/1078-0432.22439428
Autor:
Lazar Vujanovic, Denise K. Oseguera, Elizabeth Seja, Hong T. Vu, Douglas M. Potter, Antoni Ribas, Begonya Comin-Anduix, Vivian B. Dissette, John A. Glaspy, Lisa H. Butterfield, James S. Economou, Yohan Lee, Jin-Quan Yang
Publikováno v:
Journal of Immunotherapy. 31:294-309
Dendritic cells (DCs) are the key physiologic stimulators of naive and primed cells to an antigen.1,2 Many types of myeloid DCs have been tested clinically with objective clinical responses, both partial and complete. Many current immunotherapy effor
Autor:
Benjamin Bonavida, Dan D. Vo, Antoni Ribas, William H. McBride, James S. Economou, Vivian B. Dissette, Hermes Garban, Begoña Comin-Anduix, Lana Y. Schumacher, Sharla K. Owens, John A. Glaspy
Publikováno v:
The Journal of Immunology. 176:4757-4765
Proteasome inhibition results in proapoptotic changes in cancer cells, which may make them more sensitive to immune effector cells. We established a murine model to test whether the proteasome inhibitor bortezomib could sensitize established B16 mela
Autor:
Georgette M. Buga, James S. Economou, Vivian B. Dissette, John A. Glaspy, Lisa H. Butterfield, William H. McBride, Antoni Ribas, Louis J. Ignarro, Saral N. Amarnani
Publikováno v:
Cancer Gene Therapy. 9:875-883
Genetic immunotherapy with tumor antigen gene-modified dendritic cells (DC) generates robust immunity, although antitumor protection is not complete in all models. Previous experience in a model in which C57BL/6 mice immunized with DC transduced with
Publikováno v:
The Journal of Immunology. 166:3564-3573
The discovery of human melanoma rejection Ags has allowed the rational design of immunotherapeutic strategies. One such Ag, MART-1, is expressed on >90% of human melanomas, and CTL generated against MART-127–35 kill most HLA A2.1+ melanoma cells. H
Autor:
William H. McBride, Lisa H. Butterfield, Justin B. Heller, James S. Economou, John A. Glaspy, Antoni Ribas, Vivian B. Dissette, Wilson S. Meng
Publikováno v:
Molecular Immunology. 37:943-950
Human alpha-fetoprotein (AFP) is a potentially important target for the immunotherapy of hepatocellular carcinoma (HCC). AFP(542-550) (GVALQTMKQ) is one of several HLA-A2.1-restricted immunodominant AFP peptides that consistently generate AFP-specifi
Autor:
Saral N. Amarnani, Antoni Ribas, John A. Glaspy, Andrew Koh, Billy Hu, Vivian B. Dissette, William H. McBride, Angela Y. Chen, Lisa H. Butterfield, James S. Economou
Publikováno v:
Journal of Immunotherapy. 23:59-66
Summary: The murine melanoma B16 expresses the murine counterpart of the human MART-1/Melan-A (MART-1) antigen, sharing a 68.6% amino acid sequence identity. In this study, mice were vaccinated with bone marrow–derived murine dendritic cells geneti
Autor:
Vivian B. Dissette, James S. Economou, William H. McBride, Charles M. Vollmer, Antoni Ribas, Andrew Koh, Billy Hu, John A. Glaspy, Angela Y. Chen, Lisa H. Butterfield
Publikováno v:
Cancer Gene Therapy. 6:523-536
A murine model of dendritic cell (DC)-based genetic immunization to a defined human melanoma antigen (Ag), MART-1/Melan-A (MART-1), was developed. The MART-1 gene was stably transfected into the nonimmunogenic mouse fibrosarcoma cell line NFSA that i
Autor:
Aiko Tan, Lawrence T. Feldman, Nigel T. Maidment, David C. Bloom, Jack G. Stevens, Vivian B. Dissette
Publikováno v:
Molecular Brain Research. 31:48-60
A problem in utilizing herpes simplex virus (HSV) as a vector for expression of foreign genes in CNS neurons has been the inability to facilitate long-term expression of the engineered genes. Previously, we showed that the murine moloney leukemia vir