Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Vivian, Reyes"'
An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction
Autor:
Liu, Zhonglin, Sammani, Saad, Barber, Christy J., Kempf, Carrie L., Li, Feng, Yang, Zhen, Bermudez, Rosendo T., Camp, Sara M., Herndon, Vivian Reyes, Furenlid, Lars R., Martin, Diego R., Garcia, Joe G.N.
Publikováno v:
In Biomedicine & Pharmacotherapy January 2024 170
An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction
Autor:
Zhonglin Liu, Saad Sammani, Christy J. Barber, Carrie L. Kempf, Feng Li, Zhen Yang, Rosendo T. Bermudez, Sara M. Camp, Vivian Reyes Herndon, Lars R. Furenlid, Diego R. Martin, Joe G.N. Garcia
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116103- (2024)
Myocardial infarction (MI) triggers adverse ventricular remodeling (VR), cardiac fibrosis, and subsequent heart failure. Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is postulated to play a significant role in VR processing via activ
Externí odkaz:
https://doaj.org/article/753ce422727742c191c8d65e09413c14
Autor:
Heather Lynn, Xiaoguang Sun, Nancy G. Casanova, Christian Bime, Vivian Reyes Hernon, Clayton Lanham, Radu C. Oita, Nikolas Ramos, Belinda Sun, Dawn K. Coletta, Sara M. Camp, Jason H. Karnes, Nathan A. Ellis, Joe G.N. Garcia
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 17 (2023)
Background and objectives: eNAMPT (extracellular nicotinamide phosphoribosyltransferase), a novel DAMP and TLR4 ligand, is a druggable ARDS therapeutic target with NAMPT promoter SNPs associated with ARDS severity. This study assesses the previously
Externí odkaz:
https://doaj.org/article/849ab1d49b8642a68a02692ad67fb7cb
Autor:
Mohamed Ahmed, Nancy G. Casanova, Nahla Zaghloul, Akash Gupta, Marisela Rodriguez, Ian R. Robbins, Carrie L. Kempf, Xiaoguang Sun, Jin H. Song, Vivian Reyes Hernon, Saad Sammani, Sara M. Camp, Alvaro Moreira, Chaur-Dong Hsu, Joe G. N. Garcia
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Intra-amniotic inflammation (IAI) or chorioamnionitis is a common complication of pregnancy producing significant maternal morbidity/mortality, premature birth and neonatal risk of chronic lung diseases such as bronchopulmonary dysplasi
Externí odkaz:
https://doaj.org/article/62a0248f88ae4d11829680eb9c2ceaaa
Autor:
Christian Bime, Nancy G. Casanova, Sara M. Camp, Radu C. Oita, Juliet Ndukum, Vivian Reyes Hernon, Dong Kyu Oh, Yansong Li, Phil J. Greer, David C. Whitcomb, Georgios I. Papachristou, Joe G. N. Garcia
Publikováno v:
BMC Anesthesiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Nicotinamide phosphoribosyltransferase (NAMPT) exhibits dual functionality – as an intracellular enzyme regulating nicotinamide adenine dinucleotide metabolism and as an extracellular secreted protein (eNAMPT) to function as a c
Externí odkaz:
https://doaj.org/article/4a9a6cb92cbb42b3867fe595c78e81c3
Autor:
Garcia, Alexander N., Casanova, Nancy G., Valera, Daniel G., Sun, Xiaoguang, Song, Jin H., Kempf, Carrie L., Moreno-Vinasco, Liliana, Burns, Kimberlie, Bermudez, Tadeo, Valdez, Mia, Cuellar, Genesis, Gregory, Taylor, Oita, Radu C., Hernon, Vivian Reyes, Barber, Christy, Camp, Sara M., Martin, Diego, Liu, Zhonglin, Bime, Christian, Sammani, Saad, Cress, Anne E., Garcia, Joe GN
Publikováno v:
In Translational Research January 2022 239:44-57
Autor:
Tadeo Bermudez, Saad Sammani, Jin H. Song, Vivian Reyes Hernon, Carrie L. Kempf, Alexander N. Garcia, Jessica Burt, Matthew Hufford, Sara M. Camp, Anne E. Cress, Ankit A. Desai, Viswanathan Natarajan, Jeffrey R. Jacobson, Steven M. Dudek, Leopoldo C. Cancio, Julie Alvarez, Ruslan Rafikov, Yansong Li, Donna D. Zhang, Nancy G. Casanova, Christian Bime, Joe G. N. Garcia
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Despite encouraging preclinical data, therapies to reduce ARDS mortality remains a globally unmet need, including during the COVID-19 pandemic. We previously identified extracellular nicotinamide phosphoribosyltransferase (eNAMPT) as a novel
Externí odkaz:
https://doaj.org/article/092e7e48d86844b5b1f80cb4299618f7
Autor:
Gantsetseg Tumurkhuu, Nancy G. Casanova, Carrie L. Kempf, Duygu Ercan Laguna, Sara M. Camp, Jargalsaikhan Dagvadorj, Jin H. Song, Vivian Reyes Hernon, Cristina Travelli, Erica N. Montano, Jeong Min Yu, Mariko Ishimori, Daniel J. Wallace, Saad Sammani, Caroline Jefferies, Joe G.N. Garcia
Publikováno v:
Journal of Translational Autoimmunity, Vol 6, Iss , Pp 100181- (2023)
Rationale: Effective therapies to reduce the severity and high mortality of pulmonary vasculitis and diffuse alveolar hemorrhage (DAH) in patients with systemic lupus erythematosus (SLE) is a serious unmet need. We explored whether biologic neutraliz
Externí odkaz:
https://doaj.org/article/8b7438a4b64745b39ec0c97c6e32db85
Autor:
Mohamed Ahmed, Nahla Zaghloul, Prisca Zimmerman, Nancy G. Casanova, Xiaoguang Sun, Jin H. Song, Vivian Reyes Hernon, Saad Sammani, Franz Rischard, Olga Rafikova, Ruslan Rafikov, Ayako Makino, Carrie L. Kempf, Sara M. Camp, Jian Wang, Ankit A. Desai, Yves Lussier, Jason X.‐J. Yuan, Joe G.N. Garcia
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-14 (2021)
Pharmacologic interventions to halt/reverse the vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension (PAH) remains an unmet need. We previously demonstrated extracellular nicotinamide phosphoribosyltransferase (eNA
Externí odkaz:
https://doaj.org/article/01ea69ffb6ab44d592257d77dde80f26
Autor:
Nancy G. Casanova, Vivian Reyes-Hernon, Taylor Gregory, Belinda Sun, Tadeo Bermudez, Matthew K. Hufford, Radu C. Oita, Sara M. Camp, Gabriela Hernandez-Molina, Jorge Rojas Serrano, Xiaoguang Sun, Jocelyn Fimbres, Mehdi Mirsaeidi, Saad Sammani, Christian Bime, Joe G. N. Garcia
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundProgressive pulmonary fibrosis is a serious complication in subjects with sarcoidosis. The absence of reliable, non-invasive biomarkers that detect early progression exacerbates the difficulty in predicting sarcoidosis severity. To potentia
Externí odkaz:
https://doaj.org/article/a459915c163a499281650c9cdf562b49