Association between low hemoglobin, clinical measures, and patient-reported outcomes in patients with rheumatoid arthritis: results from post hoc analyses of three phase III trials of sarilumab

Autor: Andrea Rubbert-Roth, Daniel E. Furst, Stefano Fiore, Amy Praestgaard, Vivian Bykerk, Clifton O. Bingham, Christina Charles-Schoeman, Gerd Burmester

Publikováno v: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)

Abstract Background Anemia is common in patients with rheumatoid arthritis (RA). Higher hemoglobin (Hb) levels may be associated with better clinical outcomes and patient-reported outcomes (PROs). To assess this hypothesis, we conducted two post hoc

Externí odkaz: https://doaj.org/article/2297141dda5546b58a1730ec37efc1ff

Higher Checkpoint Inhibitor Arthritis Disease Activity may be Associated With Cancer Progression: Results From an Observational Registry

Autor: Karmela Kim Chan, Aidan Tirpack, Gregory Vitone, Caroline Benson, Joseph Nguyen, Nilasha Ghosh, Deanna Jannat‐Khah, Vivian Bykerk, Anne R. Bass

Publikováno v: ACR Open Rheumatology, Vol 2, Iss 10, Pp 595-604 (2020)

Objective To describe clinical features associated with cancer outcomes of patients with immune checkpoint inhibitor (ICI)‐associated arthritis. Methods Observational study of patients with ICI‐arthritis enrolled in a single‐center registry. Ar

Externí odkaz: https://doaj.org/article/ffcb37ed6fc54469b0a2bda001a24f3e

Joint Estimation of Remission and Response for Methotrexate‐Based DMARD Options in Rheumatoid Arthritis: A Bivariate Network Meta‐Analysis

Autor: Gyanendra Pokharel, Rob Deardon, Cheryl Barnabe, Vivian Bykerk, Susan J Bartlett, Louis Bessette, Gilles Boire, Carol A Hitchon, Edward Keystone, Janet Pope, Orit Schieir, Diane Tin, Carter Thorne, Glen S Hazlewood, the Canadian Early Arthritis Cohort (CATCH) Investigators

Publikováno v: ACR Open Rheumatology, Vol 1, Iss 8, Pp 471-479 (2019)

Objective To jointly estimate American College of Rheumatology (ACR50) response (a more commonly reported outcome) and remission (a more clinically relevant outcome) for methotrexate (MTX)‐based treatment options in rheumatoid arthritis (RA). Metho

Externí odkaz: https://doaj.org/article/9d6129ea265746cfa78c1e4c74ffdac7

Modification of immunomodulatory medications by rheumatology patients during the peak of the COVID-19 pandemic in New York City

Autor: Medha Barbhaiya, Marianna B. Frey, Jonah Levine, Gregory Vitone, Lindsay Lally, Michael D. Lockshin, Vivian Bykerk, Candace H. Feldman, Lisa A. Mandl

Publikováno v: Clinical Rheumatology. 41:2597-2599

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52b60ad51638691376fdbd0b55ce9884
https://doi.org/10.1007/s10067-022-06203-1

Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions

Autor: Daniel Aletaha, Andreas Kerschbaumer, Kastriot Kastrati, Christian Dejaco, Maxime Dougados, Iain B McInnes, Naveed Sattar, Tanja A Stamm, Tsutomu Takeuchi, Michael Trauner, Désirée van der Heijde, Marieke Voshaar, Kevin L Winthrop, Angelo Ravelli, Neil Betteridge, Gerd-Rüdiger R Burmester, Johannes WJ Bijlsma, Vivian Bykerk, Roberto Caporali, Ernest H Choy, Catalin Codreanu, Bernard Combe, Mary K Crow, Maarten de Wit, Paul Emery, Roy M Fleischmann, Cem Gabay, Merete Lund Hetland, Kimme L Hyrich, Annamaria Iagnocco, John D Isaacs, Joel M Kremer, Xavier Mariette, Peter A Merkel, Eduardo F Mysler, Peter Nash, Michael T Nurmohamed, Karel Pavelka, Gyula Poor, Andrea Rubbert-Roth, Hendrik Schulze-Koops, Anja Strangfeld, Yoshiya Tanaka, Josef S Smolen

Publikováno v: Annals of the rheumatic diseases. BMJ
Aletaha, D, Kerschbaumer, A, Kastrati, K, Dejaco, C, Dougados, M, McInnes, I B, Sattar, N, Stamm, T A, Takeuchi, T, Trauner, M, van der Heijde, D S, Voshaar, M, Winthrop, K L, Ravelli, A, Betteridge, N, Burmester, G-R D R, Bijlsma, J W J, Bykerk, V, Caporali, R, Choy, E H, Codreanu, C, Combe, B, Crow, M K, de Wit, M, Emery, P, Fleischmann, R M, Gabay, C, Hetland, M L, Hyrich, K L, Iagnocco, A, Isaacs, J D, Kremer, J M, Mariette, X, Merkel, P, Mysler, E F, Nash, P, Nurmohamed, M T, Pavelka, K, Poor, G, Rubbert-Roth, A, Schulze-Koops, H, Strangfeld, A, Tanaka, Y & Smolen, J S 2022, ' Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions : an update ', Annals of the Rheumatic Diseases . https://doi.org/10.1136/ard-2022-222784
Annals of the Rheumatic Diseases. BMJ PUBLISHING GROUP
Annals of the Rheumatic Diseases
Aletaha, D, Kerschbaumer, A, Kastrati, K, Dejaco, C, Dougados, M, McInnes, I B, Sattar, N, Stamm, T A, Takeuchi, T, Trauner, M, Van Der Heijde, D, Voshaar, M, Winthrop, K L, Ravelli, A, Betteridge, N, Burmester, G R R, Bijlsma, J W J, Bykerk, V, Caporali, R, Choy, E H, Codreanu, C, Combe, B, Crow, M K, De Wit, M, Emery, P, Fleischmann, R M, Gabay, C, Hetland, M L, Hyrich, K L, Iagnocco, A, Isaacs, J D, Kremer, J M, Mariette, X, Merkel, P, Mysler, E F, Nash, P, Nurmohamed, M T, Pavelka, K, Poor, G, Rubbert-Roth, A, Schulze-Koops, H, Strangfeld, A, Tanaka, Y & Smolen, J S 2023, ' Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions : an update ', Annals of the Rheumatic Diseases, vol. 82, no. 6, pp. 773–787 . https://doi.org/10.1136/ard-2022-222784
Annals of the Rheumatic Diseases. BMJ Publishing Group

BackgroundTargeting interleukin (IL)-6 has become a major therapeutic strategy in the treatment of immune-mediated inflammatory disease. Interference with the IL-6 pathway can be directed at the specific receptor using anti-IL-6Rα antibodies or by d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5450f45d4f38f87158cb07200a3b129
https://doi.org/10.1136/ard-2022-222784