Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Viveka Tillgren"'
Autor:
Rebecca Mae Black, Yang Wang, André Struglics, Pilar Lorenzo, Viveka Tillgren, Martin Rydén, Alan J. Grodzinsky, Patrik Önnerfjord
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 4, Pp 100099- (2020)
Summary: Objectives: In this exploratory study, we used discovery proteomics to follow the release of proteins from bovine knee articular cartilage in response to mechanical injury and cytokine treatment. We also studied the effect of the glucocortic
Externí odkaz:
https://doaj.org/article/15cb81ecb47d4e6cbfdb7673cf7b5853
A human meniscus explant model for studying early events in osteoarthritis development by proteomics
Autor:
Martin Rydén, Karin Lindblom, Aida Yifter‐Lindgren, Aleksandra Turkiewicz, Anders Aspberg, Viveka Tillgren, Martin Englund, Patrik Önnerfjord
Publikováno v:
Journal of Orthopaedic Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0533d0e89f88ff691b18b304fe8df519
https://doi.org/10.1002/jor.25633
https://doi.org/10.1002/jor.25633
Autor:
Martin Rydén, Rebecca Mae Black, Pilar Lorenzo, André Struglics, Patrik Önnerfjord, Viveka Tillgren, Alan J. Grodzinsky, Yang Wang
Publikováno v:
Osteoarthr Cartil Open
Osteoarthritis and Cartilage Open, Vol 2, Iss 4, Pp 100099-(2020)
Osteoarthritis and Cartilage Open, Vol 2, Iss 4, Pp 100099-(2020)
Summary Objectives In this exploratory study, we used discovery proteomics to follow the release of proteins from bovine knee articular cartilage in response to mechanical injury and cytokine treatment. We also studied the effect of the glucocorticoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff27d5e7fe59fd58d91c5e96365c61f
https://europepmc.org/articles/PMC8315049/
https://europepmc.org/articles/PMC8315049/
Publikováno v:
Acta Crystallographica Section D Structural Biology. 73:53-63
Chondroadherin (CHAD) is a cartilage matrix protein that mediates the adhesion of isolated chondrocytes. Its protein core is composed of 11 leucine-rich repeats (LRR) flanked by cysteine-rich domains. CHAD makes important interactions with collagen a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f87208576497e109b43f5e115529f9a
https://doi.org/10.1107/s205979831601980x
https://doi.org/10.1107/s205979831601980x
Autor:
Patrik Önnerfjord, Kaare M. Gautvik, Nadia Rucci, Viveka Tillgren, Dick Heinegård, Mattia Capulli, Ole Kristoffer Olstad, Anna Teti
Publikováno v:
Cancer Letters. 358:67-75
cyclicCHAD is a peptide representing the α2β1 integrin binding sequence of the matrix protein chondroadherin (CHAD), which in our hands proved effective at counteracting bone loss in ovariectomised mice by inhibiting osteoclastogenesis. Given that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e55e736ed71dc5b018d2d18e5b36cd4
https://doi.org/10.1016/j.canlet.2014.12.032
https://doi.org/10.1016/j.canlet.2014.12.032
Autor:
Viveka Tillgren, Anna Teti, Maurizio Muraca, Nadia Rucci, Ole Kristoffer Olstad, Mattia Capulli, Kaare M. Gautvik, Dick Heinegård, Patrik Önnerfjord
Publikováno v:
Journal of Bone and Mineral Research. 29:1833-1846
Chondroadherin (CHAD) is a leucine-rich protein promoting cell attachment through binding to integrin α2 β1 and syndecans. We observed that CHAD mRNA and protein were lower in bone biopsies of 50-year-old to 65-year-old osteoporotic women and in bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a6167cf9740e807bbe9d4955c8e3d1
https://doi.org/10.1002/jbmr.2206
https://doi.org/10.1002/jbmr.2206
Autor:
Mattia Capulli, Luca Ventura, Viveka Tillgren, Adriano Angelucci, Anna Teti, Maurizio Muraca, Nadia Rucci, Barbara Peruzzi, Dick Heinegård
Publikováno v:
Journal of Bone and Mineral Research. 28:1912-1924
(hbd) PRELP is a peptide corresponding to the N-terminal heparin binding domain of the matrix protein proline/arginine-rich end leucine-rich repeat protein (PRELP). (hbd) PRELP inhibits osteoclastogenesis entering pre-fusion osteoclasts through a cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2517dc973da7a7f5d3adfc41f0289b6
https://doi.org/10.1002/jbmr.1951
https://doi.org/10.1002/jbmr.1951
Publikováno v:
The Journal of biological chemistry. 291(45)
Small leucine-rich proteoglycans interact with other extracellular matrix proteins and are important regulators of matrix assembly. Fibromodulin has a key role in connective tissues, binding collagen through two identified binding sites in its leucin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a5f8eed34456ad50bdbcd675f83297
https://pubmed.ncbi.nlm.nih.gov/27634037
https://pubmed.ncbi.nlm.nih.gov/27634037
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry; 288(2), pp 995-1008 (2013)
Journal of Biological Chemistry; 288(2), pp 995-1008 (2013)
Chondroadherin, a leucine-rich repeat family member, contains a very C-terminal sequence CKFPTKRSKKAGRH(359), now shown to bind to heparin with a K-D of 13 mu M. This observation led us to investigate whether chondroadherin interacts via this C-termi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6659da6e3dbf211eb258154ec9d0482
Autor:
Viveka Tillgren, Laura Addis, L. Haglund, Anneliese D. Recklies, Christina Wenglén, Dick Heinegård
Publikováno v:
Journal of Biological Chemistry. 286:3925-3934
Chondroadherin is a leucine-rich repeat protein known to mediate adhesion of isolated cells via the integrin α(2)β(1) and to interact with collagen. In this work, we show that cell adhesion to chondroadherin leads to activation of MAPKs but does no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b80e282dd4fe3d0c5ace8df7efcebd7
https://doi.org/10.1074/jbc.m110.161141
https://doi.org/10.1074/jbc.m110.161141